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(Please note varying room designations.)

September '08
17	BRB 253 12:00 - 1:00		Cai L., Makhov A.M., Schafer D.A., Bear J.E. Coronin 1B Antagonizes Cortactin and Remodels Arp2/3-Containings Actin Branches in Lamellipodia. J. Cell, 2008	Michael Ostap
24	BRB-801 Conf. room 12:00 - 1:00		Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D. Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes Dev. 2008 Aug 15;22(16):2189-203. Epub 2008 Jul 28.	Jennine McKenna
October '08
08	Steller-Chance 104 Conf room 12:00 - 1:00		Oguchi Y, Mikhailenko SV, Ohki T, Olivares AO, De La Cruz EM, Ishiwata S. Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function. PNAS	John Beausang
15	BRB 253 12:00 - 1:00		Dietrich et al., "The kinesin-1 motor protein is regulated by a direct interaction of its head and tail". PNAS 105, 8938-8943, 2008	Daniel Safer
29	Steller-Chance 104 Conf room 12:00 - 1:00		Yildiz A, Tomishige M, Gennerich A, Vale RD. Intramolecular strain coordinates kinesin stepping behavior along microtubules. Cell 134, 1030-1041	Serapion Pyrpassopoulos
				Serapion Pyrpassopoulos
November '08
05	Steller-Chance 104 Conf room 12:00 - 1:00	Stanislav Nagy, Benjamin L. Ricca, Melanie F. Norstrom, David S. Courson, Crista M. Brawley, Philip A. Smithback, and Ronald S. Rock. A myosin motor that selects bundled actin for motility. PNAS 28, 9616-9620		Yugie Sun
26	Room - BRB II/III 253		The actin regulator coronin 1A is mutant in a thymic egress eficient mouse strain and in a patient with severe combined immunodeficiency. NATURE IMMUNOLOGY VOL 9 1307-1315. Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Ying Xu1, Jenne CN, Foger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, & Cyster	Gregory Rak
December '08
03	BRB 253 12:00 - 1:00		title	presenter
03	BRB 253 12:00 - 1:00		title	Ashley Mentlik
10	Steller-Chance 104 Conf room 12:00 - 1:00		Tooley AJ, Gilden J, Jacobelli J, Beemiller P, Trimble WS, Kinoshita M, Krummel MF. Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility. Nat Cell Biol. 2008	Ashley Mentlik
January '09
14	BRB 251 12:00 - 1:00		Wu X, Kodama A, Fuchs E. ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell, 2008	Erika Holzbaur
21	BRB 251 12:00 - 1:00		Carter AP, Garbarino JE, Wilson-Kubalek EM, Shipley WE, Cho C, Milligan RA, Vale RD, and Gibbons IR. Structure and functional role of dynein's microtubule-binding domain. Science, 2008 Amos LA. Pressing levers or pulling strings? Science. 2008	Dan Safer
28	BRB 251 12:00 - 1:00		George T. Shubeita, et al. 2008. Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets. Cell 135, 1098-1107.	Adam Hendricks
February '09
04	BRB 901 12:00 - 1:00		Oda T, Iwasa M, Aihara T, Maeda Y, Narita A. The nature of the globular-to fibrous-actin transition. Nature 2009.	Joe Laasko
11	BRB 901 12:00 - 1:00		Foe VE and von Dassow, G. Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation. J. Cell Biol. 2008	Jennine McKenna
25	BRB 901 12:00 - 1:00		Roberts AJ, Numata N, Walker ML, Kato YS, etal. AAA+ Ring and linker swing mechanism in the dynein motor. Cell 136, 485-495	John Beausang
March '09
11	Room - BRB II/III 251		BIOPHYSICS SUMMARY
18	BRB 251 12:00 - 1:00		Llobet A, Wu M, and Lagnado L. The mouth of a dense-core vesicle opens and closes in a concerted action regulated by calcium and amphiphysin. J Cell Biology, 182:1017-1028, 2008.	Clara Franzini-Armstrong
25	BRB 251 12:00 - 1:00		Greene GW, Anderson TH, Zeng H, Zappone B, and Israelachvili JN. Force amplification response of actin filaments under confined compression. PNAS, 106:445-449	Serapion Pyrpassopoulos
April '09
01	BRB 251 12:00 - 1:00		Yip FM, Ramm G, Larance M, Hoehn KL, Wagner MC, Guilhaus M and James DE. CaMKII-Mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes. Cell Metabolism, 8:384-398	Mike Ostap
08	BRB 251 12:00 - 1:00		Junker JP, Ziegler F, Rief M. Ligand-dependent equilibrium fluctuations of single calmodulin molecules. Science, 323:633-637, 2009.	John Lewis
15	BRB 251 12:00 - 1:00		Song AH, Wang D, Chen G, Li Y, Luo J, Duan S, Poo MM. A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment. Cell 136: 1148-1160, 2009.	Meng-Meng Fu
22	BRB 251 12:00 - 1:00		Lehman W, Galinski-Rakoczy A, Hatch V, Tobacman LS, Craig R. Structural basis for the activation of muscle contraction by troponin and tropomyosin. J Mol Biol [ahead of print] 2009	Yale Goldman
29	BRB 251 12:00 - 1:00		Ilani T, Vasiliver-Shamis G, Vardhana S, Bretscher A, & Dustin ML. T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nature Immunology, 10:531-539, 2009.	Ashley Mentlik
29	BRB 251 12:00 - 1:00
May '09
06	BRB 253 12:00 - 1:00		Konishi Y. & Setou M. Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nature Neuroscience, 12:559-56, 2009. Lewis Jr, TL, Mao T, Svoboda K, & Arnold DB. Myosin-dependent targeting of transmembrane proteins to neuronal dendrites. 12:568-576, 2009.	Trey Schroeder
13	BRB 253 12:00 - 1:00		Weisswange I., Newsome T.P., Schleich S., and Way, M. The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motilit. Nature 458, 87-91	Beth Feeser
20			NO JOURNAL CLUB
27	BRB 253 12:00 - 1:00		Iwaki M, Iwane AH, Shimokawa T, Cooke R, Yanagida. Brownian search-and-catch mechanism for myosin-VI steps. Nature Chemical Biology 5, 403-405	Ping Phichith
June '09
03	BRB 253 12:00 - 1:00	Kerber ML, Jacobs DT, Campagnola L, Dunn BD, Yin T, Sousa AD, Quintero OA, Cheney RE. A Novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level. Current Biology 19, 1-7, June 9, 2009		Yujie Sun
17	BRB 901 Conf Rm 12:00 - 1:00	Sun Y, McKenna JD, Murray JM, Ostap EM, Goldman YE. Parallax: High AccuracyThree-Dimensional Single Molecule Tracking Using Split Images. Nano Lett. 2009 Jun 4. [Epub ahead of print] PubMed PMID: 19496608.		Yale Goldman
24	BRB 252 12:00 - 1:00	Bornschlögl, Woehlke G, and Rief M. Single molecule mechanics of the kinesin neck. PNAS 106, 6992-6997		Chris Mitchell
July '09
1	BRB 801 Conf Rm 12:00 - 1:00	Chen, I.A. Cell Division: Breaking up is easy to do. Current Biology 19, R327 Leaver M, Dominguez-Cuevas P, Coxhead JM, Daniel RA, Errington J. Life without a wall or division machine in Bacillus subtilis. Nature 457, 849-853		Daniel Safer
8	BRB 801 Conf Rm 12:00 - 1:00	Krauss J, Lopez de Quinto S, Nüsslein-Volhard C, and Ephrussi A. Myosin-V regulates oskar mRNA localization in the drosophila Oocyte. Current Biology 19, 1058-1063, 2009. Satoh AK, LI BX, Xia H, Ready DF. Calcium-activated myosin V closes the drosphila pupil. Curr Biol. 13, 951-955, 2008.		John Beausang
15	BRB 1001 Conf Rm 12:00 - 1:00	Brawley CM, Rock RS. Unconventional myosin traffic in cells reveals a selective actin cytoskeleton. PNAS 106, 9685-9690, 2009.		John Lewis
22	BRB 801 Conf Rm 12:00 - 1:00	Current Topics in Cell Motility		Erika Holzbaur
29	BRB 801 Conf Rm 12:00 - 1:00	Peris L, Wagenbach M, Lafanechère L, Brocard J, Moore AT, Kozielski F, Job D, Wordeman L, Andrieux A. Motor-dependent microtubule disassembly driven by tubulin tyrosination. J Cell Biol. 185(7):1159-66. 2009		Jacob Lazarus
August '09
5	BRB 252 12:00 - 1:00	Bellett G, Carter JM, Keynton J, Goldspink D, James C, Moss DK, Mogensen MM. Cell Motil Cytoskeleton. 2009 May 28. [Epub ahead of print] Microtubule Plus-End and Minus-End Capture at Adherens Junctions is Involved in the Assembly of Apico-Basal Arrays in Polarised Epithelial Cells		Meredith Wilson
12	BRB 252 12:00 - 1:00	CANCELLED		Adam Hendricks
19	BRB 252 12:00 - 1:00	Yu C, Feng W, Wei Z, Miyanoiri Y, Wen W, Zhao Y, Zhang M. Myosin VI undergoes cargo-mediated dimerization. Cell. 2009 Aug 7;138(3):537-48.		Jennine Dawicki-McKenna
26	BRB 252 12:00 - 1:00	Nambiar R, McConnell RE, Tyska MJ. Control of cell membrane tension by myosin-I. PNAS 2009 July 21;106 (29): 11972-11977.		Serapion Pyrpassopoulos

Pennsylvania Muscle Institute
Perelman School of Medicine

University of Pennsylvania
Director: E. Michael Ostap, Ph.D.
700A Clinical Research Building

Philadelphia, PA 19104-6085

Phone: (215) 573-9758

Fax: (215) 898-2653