Penn Medicine
 

Journal Club Archive: 2010 - 2011

Current | 2013/2014 | 2012/2013 | 2011/2012 | 2010/2011 | 2009/2010 | 2008/2009 | 2007/2008 | 2006/2007 | 2005/2006  
   
July | August | Sept | Oct | Nov | Dec | Jan | Feb | March | April | May | June  

(Please note varying room designations.)

July '10
9
7 BRB 253
12:00 - 1:00

No Journal Club

   
         
14 BRB 253
12:00 - 1:00

Melanie J. I. Müller, Stefan Klumpp, and Reinhard Lipowsky
Bidirectional Transport by Molecular Motors: Enhanced Processivity and Response to External Forces
Biophysical Journal 2010 (98):2610–2618

  Adam Hendricks
         
21 BRB 253
12:00 - 1:00

Lund K, Manzo AJ, Dabby N, Michelotti N, Johnson-Buck A, Nangreave J, Taylor S, Pei R, Stojanovic MN, Walter NG, Winfree E & Yan H. Molecular robots guided by prescriptive landscapes. Nature (May 13 2010) 465:206-210.

  John Lewis
         
28 BRB 251
12:00 - 1:00

Kollman JM, Polka JK, Zelter A, Davis TN, Agard DA. Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetry.  Nature. 2010 Jul 14. [Epub ahead of print]

  Trey Schroeder
         
August '10
9
4 BRB 251
12:00 - 1:00

Dunn AR, Chuan P, Bryant Z, and Spudich JA. Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing. PNAS 107:7746-7750.

  Lisa Lippert
         
11 BRB 251
12:00 - 1:00
Pertsinidis A, Zhang Y & Chu S. Subnanometre single-molecule localization,
registration and distance measurements. 466:647-51
  John Beausang
         
18 BRB 251
12:00 - 1:00
Martin AC, Gelbart M, Fernandez-Gonzalez R, Kaschube M, Wieschaus EF.
Integration of contractile forces during tissue invagination.
J Cell Biol. 2010 Mar 8;188(5):735-49. Epub 2010 Mar 1.
  Jennine Dawicki-McKenna
         
25 D502 conf room Richards Bldg.
12:00 - 1:00
Kaya M, Higuchi H. Nonlinear elasticity and an 8-nm working stroke of single myosin molecules in myofilaments. Science. 2010 Aug 6;329(5992):686-9.   Mike Ostap
Sept '10
9
1 D502 conf room Richards Bldg.
12:00 - 1:00

Clayton JE, Sammons MR, Stark BC, Hodges AR, Lord M. Differential Regulation of Unconventional Fission Yeast Myosins via the Actin Track. Curr Biol. 2010 Aug 11. [Epub ahead of print]

  Beth Feeser
         
8 D502 conf room Richards Bldg.
12:00 - 1:00
Rex CS, Gavin CF, Rubio MD, etal. Myosin IIb Regulates Actin Dynamics during Synaptic Plasticity and Memory Formation. Volume 67, Issue 4, 603-617, 26 August 2010

  Allison Zajac
         
15 D502 conf room Richards Bldg.
12:00 - 1:00
Kim Y, Holland AJ, Lan W and Cleveland DW. Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E. Cell, 2010 142:444-455.   Katya Grishchuk
         
22 D502 conf room Richards Bldg.
12:00 - 1:00

Ptacin JL, Lee SF, Garner EC, Toro E, Eckart M, Comolli LR.
A spindle-like apparatus guides bacterial chromosome segregation.  Nature Cell Biology (2010) 12:791

  Daniel Safer
         
29 D502 conf room Richards Bldg.
12:00 - 1:00

NO JOURNAL CLUB

   
October '10
9
6 D502 conf room Richards Bldg.
12:00 - 1:00

Astumian, R.D.  Thermodynamics and kinetics of molecular motors.
Biophys J. 2010, 98(11) pp. 2401 - 2409

  Anatoly Zaytsev
         
13 D502 conf room Richards Bldg.
12:00 - 1:00

N.V. Bukoreshtliev, X. Wang, E. Hodneland, S. Gurke, J.FV. Barroso,H. Gerdes.
Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells.  FEBS Letters 583 (2009) 1481–1488.

X. Wang, M.L. Veruki, N.V. Bukoreshtliev, E. Hartveit, and H. Gerdes. Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels.  PNAS,October 5, 2010 107(40):17194–17199

  Denis Phichith
         
20 D502 conf room Richards Bldg.
12:00 - 1:00

Li H, Liu XS, Yang X, Song B, Wang Y, Liu X. Polo-like kinase 1 phosphorylation of p150(glued) facilitates nuclear envelope breakdown during prophase. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14633-8.

Romé P, Montembault E, Franck N, Pascal A, Glover DM, Giet R. Aurora A contributes to p150(glued) phosphorylation and function during mitosis. J Cell Biol. 2010 May 17;189(4):651-9.

  Jacob Lazarus
         
27 D502 conf room Richards Bldg.
12:00 - 1:00
Min Wu, Bo Huang, Morven Graham, Andrea Raimondi, John E. Heuser, Xiaowei Zhuang & Pietro De Camilli Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system Nature Cell Biology Letter Vol 12:902–908 (2010)   Serapion Pyrpassopoulos
November '10
9
3 D502 conf room Richards Bldg.
12:00 - 1:00
Kodera N, Yamamoto D, Ishikawa R & Ando T. Video imaging of walking myosin V by high-speed atomic force microscopy. Nature. Epub. October 10, 2010   Michael Greenberg
         
10 D502 conf room Richards Bldg.
12:00 - 1:00
Nishikawa S, Arimoto I, Ikezaki K, etal. Switch between large hand-over-hand and small inchworm-like steps in myosin VI. Cell 2010, 142(6):879-888   Lisa Lippert
         
17 D502 conf room Richards Bldg.
12:00 - 1:00
Gandhi M, Achard V, Blanchoin L, and Goode BL. Coronin switches roles in actin disassembly depending on the nucleotide state of actin. Molecular Cell, 2009 34, 364-374.   Emily Mace
         
24 D502 conf room Richards Bldg.
12:00 - 1:00
     
December '10
9
1 D502 conf room Richards Bldg.
12:00 - 1:00
Fridolfsson H.N. and Starr DA. Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei. J. Cell Biol. Vol. 191 No. 1 115–128.   Erika Holzbaur
         
8 D502 conf room Richards Bldg.
12:00 - 1:00

JNK-induced changes in axonal transport are mediated by the bidirectional co-regulator JIP1

Kinesin-like protein CENP-E adopts a folded conformation while exhibiting high motor activity

 

Meng-meng Fu


Nikita Gudimchuk

January '11
9
12 D502 conf room Richards Bldg.
12:00 - 1:00

S.E. Glynn, A. Martin, A.R. Nager, T.A. Baker, and R.T. Sauer. Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine. Cell 139, 744–756

  Tali Dadosh
         
19 D502 conf room Richards Bldg.
12:00 - 1:00

Kanchanawong P, Shtengel G, Pasapera AM, Ramko EB, Davidson MW, Hess HF, and Waterman CM. Nanoscale architecture of integrin-based cell adhesions.  Nature 468: 580–584 Date published: (25 November 2010).

  Yale Goldman
         
26 D502 conf room Richards Bldg.
12:00 - 1:00
NO JOURNAL CLUB    
February '11
9
2 D502 conf room Richards Bldg.
12:00 - 1:00
NO JOURNAL CLUB    
         
9 D502 conf room Richards Bldg.
12:00 - 1:00
NO JOURNAL CLUB    
         
16 D502 conf room Richards Bldg.
12:00 - 1:00
Goodwin SS and Vale RD. Patronin regulates the microtubule network by protecting microtubule minus ends. Cell 143, 263-274   Allison Zajac
         
23 D502 conf room Richards Bldg.
12:00 - 1:00

Aylett CHS, Wang Q, Michie KA, Amos LA, and Lowe J. Filament structure of bacterial tubulin homologue TubZ, 2010, PNAS 107, 19766-19771.

Nogales E. When cytoskeletal worlds collide, 2010, PNAS 107, 19609-19610.

  Daniel Safer
March '11
9
2 D502 conf room Richards Bldg.
12:00 - 1:00

Practice talks for Biophysics Meeting - Adam G. Hendricks, Eran Perlson, Jacob E. Lazarus, Mariko Tokito, Yale E. Goldman, Erika L. F. Holzbaur. Dynein's dual roles as a motor and tether in the neuron

 

  Adam Hendricks
         
9 D502 conf room Richards Bldg.
12:00 - 1:00
Biophysics Meeting    
         
16 D502 conf room Richards Bldg.
12:00 - 1:00
Biophysics Meeting Highlights    
23 D502 conf room Richards Bldg.
12:00 - 1:00
NO JOURNAL CLUB    
         
30 D502 conf room Richards Bldg.
12:00 - 1:00
Wong, Y.L. and Rice, S.E. Kinesins light chains inhibit the head- and microtubule-binding activity of its tail. PNAS 107(26):11781-11786   Nikita Gudimchuk
April '11
9
6 D502 conf room Richards Bldg.
12:00 - 1:00
Elting MW, Bryant Z, Liao JC, and Spudich JA. Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI. Biophysical Journal, Volume 100, January 2011, 430-439   Mike Ostap
         
13 D502 conf room Richards Bldg.
12:00 - 1:00
Carter AP, Cho C, Jin L, and Vale RD.  Crystal structure of the dynein motor domain.  Science, March 2011, Vol. 331, 1159-1165.   Lisa Lippert
         
20 D502 conf room Richards Bldg.
12:00 - 1:00
Suzuki A, Hori T, Nishino T, Usukura J, Miyagi A, Morikawa K and Fukagawa T.  Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins.  Journal of Cell Biology, Vol. 193 Issue 1, 125-140   Katya Grishchuk
27 D502 conf room Richards Bldg.
12:00 - 1:00
Mostowy S, Bonazzi M, Hamon MA, Tham TN, Mallet A, Lelek M, Gouin E, Demangel C, Brosch R, Zimmer C, Sartori A, Kinoshita M, Lecuit M, Cossart P.  Entrapment of intracytosolic bacteria by septin cage-like structures.  Cell Host Microbe. 2010 Nov 18;8(5):433-44.   Jennine Dawicki-McKenna
May '11
9
4 D502 conf room Richards Bldg.
12:00 - 1:00

Tojkander S, Gateva G, Schevzov G, Hotulainen P, Naumanen P, Martin C, Gunning PW, Lappalainen P. A Molecular Pathway for Myosin II Recruitment to Stress Fibers. Curr Biol. 2011 Apr 12;21(7):539-50. Epub 2011 Mar 31.

  Beth Feeser
         
11 D502 conf room Richards Bldg.
12:00 - 1:00
Tamada A, Kawase S, Murakami F and Kamiguchi H. Autonomous right-screw rotation of growth cone filopodia drives neurite turning. J Cell Biol 2010 Feb 8;188(3):429-41.   Deborah Shroder
         
18 D502 conf room Richards Bldg.
12:00 - 1:00

Shiroguchi K, Chin HF, Hannemann DE, Muneyuki E, De La Cruz EM, Kinosita K Jr. Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin. PLoS Biol. 2011 Apr;9(4):e1001031. Epub 2011 Apr 12.

  John Beausang
25 D502 conf room Richards Bldg.
12:00 - 1:00
Scott DA, Das U, Tang Y, and Roy S. Mechanistic logic underlying the axonal transport of cytosolic proteins. Neuron 70, 441-454.   Meng-meng Fu
         
June '11
9
1 D502 conf room Richards Bldg.
12:00 - 1:00
Erickson RP, Jia Z, Gross SP, Yu CC.   How molecular motors are arranged on a cargo is important for vesicular transport. PLoS Comput Biol. 2011 May;7(5):e1002032. Epub 2011 May 5   Erika Holzbaur
         
8 D502 conf room Richards Bldg.
12:00 - 1:00
Kozlov AS, Baumgart J, Risler T, Versteegh CP, Hudspeth AJ.  Forces between clustered stereocilia minimize friction in the ear on a subnanometre scale. Nature. 2011 May 22. [Epub ahead of print]   Adam Hendricks
         
15 D502 conf room Richards Bldg.
12:00 - 1:00
Borgia MB, Borgia A, Best RB, Steward A, Nettels D, Wunderlich B, Schuler B & Clarke J. Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins. Nature (2011) doi:10. 1038/nature 10099.   Serapion Pyrpassopoulos
22 D502 conf room Richards Bldg.
12:00 - 1:00
Roostalu J, Hentrich C, Bieling P, Telley IA, Schiebel E, and Surrey T.  switching of the kinesin Cin8 through motor coupling.  Science  April 2011: Vol. 332 no. 6025 pp. 94-99.   Swathi Ayloo
29 D502 conf room Richards Bldg.
12:00 - 1:00
Fink J, Carpi N, Betz T, Bétard A, Chebah M, Azioune A, Bornens M, Sykes C, Fetler L, Cuvelier D & Piel M.  External forces control mitotic spindle positioning.  Nature Cell Biology June 12 2011 [Epub ahead of print].   Deborah Shroder
         

 

 

 

Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653