Our Members

PMI membership consists of an extraordinarily strong interdisciplinary team of scientists that investigate muscle biology and non-muscle contractile systems. Specifically, our members use biophysics, biochemistry, genetics, physiology and ultrastructure to understand cell migration and intracellular transport, molecular motors, cell division, muscle contraction and development, muscle pathologies and therapies targeted to muscle disease.

[sorted by alphabetical order]

NAME/RESEARCH AREA

PHONE/FAX

DEPARTMENT

Charles S. Abrams, M.D.
Phospholipid signaling in platelet and T-cells

215.898.1058 (tel)
215.573.7400 (fax)

Department of Medicine, University of Pennsylvania

Zoltan P. Arany, M.D.

215.746.0127 (tel)

Department of Medicine, University of Pennsylvania

Yair Argon, Ph.D.
Control of IGF signaling in muscle

267.426.5131 (tel)
267.426.5165 (fax)

Pathology, Division: Cell Pathology, Children's Hospital of Philadelphia

Richard K. Assoian, Ph.D.
Cell adhesion and mechanotransduction in smooth muscle cells and cardiovascular biology

215.898.7157 (tel)

Department of Pharmacology, University of Pennsylvania

Robert Barsotti, Ph.D.
Smooth and cardiac muscle physiology

215.893.2368 (tel)

Department of Physiology, Neuroscience, and Pharmacology, PCOM

Stephen M. Baylor, M.D.
E-C coupling in skeletal muscle

215.898.5559 (tel)
215.573.5851 (fax)

Department of Physiology, University of Pennsylvania

Jill Beech, V.M.D.
Equine myopathies

610.444.5800 (tel)
610.925.8100 (fax)

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania

Erfei Bi, Ph.D.
Cell polarity and the control of cytokinesis

215.573.6676 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

Simona Boncompagni, Ph.D.
Ultrastructure of striated muscle

215.898.3345 (tel)
215.573.2170 (fax)

Department of Neuroscience and Clinical Imaging Sciences, Universita degli Studi "G. d'Annunzio"

Carsten G. Bönnemann, M.D.
Neuromuscular and Neurogenetic Disorders of Childhood Section

301.594.5496 (tel)
301.480.3365 (fax)

National Institute of Neurological Disorders and Stroke/NIH Porter Neuroscience Research

Timothy R. Brazelton, Ph.D.
Tissue regeneration and plasticity of adult stem cells

267.426.0201 (tel)
215.590.3324 (fax)

Department of Surgery, Children's Hospital of Philadelphia

Janis K. Burkhardt, Ph.D.
Role of the cytoskeleton in T cell function

267.426.5410 (tel)
267.426.5165 (fax)

Department of Pathology & Laboratory Medicine, University of Pennsylvania

Thomas M. Butler, Ph.D.
Control of smooth and catch muscle contraction

215.503.6583 (tel)
215.503.2073 (fax)

Department of Physiology, Thomas Jefferson University

Lynne Cassimeris, Ph.D.
Regulation of microtubule assembly

610.758.6275 (tel)
610.758.4004 (fax)

Department of Biological Sciences, Lehigh University

Samuel K. Chacko, DVM, Ph.D.
Regulation of smooth muscle

215.898.5755 (tel)
215.898.0719 (fax)

Department of Pathobiology, School of Veterinary Medicine

Margaret M. Chou, M.D.
G-Protein & cell transformations

215.573.4126 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

John C. Crocker, Ph.D.
Mechanical response of cells to applied mechanical stress

215.898.9188 (tel)
215.573.2093 (fax)

Department of Chemical and Biomolecularl Engineering, University of Pennsylvania

Dennis E. Discher, Ph.D.
Cell and molecular mechanics

215.898.4809 (tel)
215.573.2093 (fax)

Chemical/Biomolecular Engineering and Bioengineering, University of Pennsylvania

Roberto Dominguez, Ph.D.
Cytoskeleton dynamics and the linkage between the cytoskeleton, membranes and signaling

215.573.4559 (tel)

Department of Physiology, University of Pennsylvania

Jonathan A. Epstein, M.D.
Heart and muscle development

215.898.8731 (tel)
215.573.2094 (fax)

Department of Medicine, University of Pennsylvania

Alan W. Flake, M.D., FACS, FAAP
Stem cell and gene therapy

215.590.3671 (tel)
215.590.3324 (fax)

Center for Fetal Diagnosis and Treatment, Surgery, Children's Hospital of Philadelphia

Clara Franzini-Armstrong, Ph.D.
Ultrastructure of striated muscle

215.898.3345 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

Yale E. Goldman, M.D., Ph.D.
Molecular mechanism of muscle contraction

215.898.4017 (tel)
215.898.2653 (fax)

Department of Physiology, University of Pennsylvania

Matthew C. Good, Ph.D.
Size scaling, spatial organization of cells, cytoskeleton, signaling

215-573-1099 (tel)

Department of Cell and Developmental Biology
Department of Bioengineering University of Pennsylvania

Ekaterina Grishchuk, Ph.D.
Biophysics of cell division

215.746.8178 (tel)
215.573.2273 (fax)

Department of Physiology, University of Pennsylvania

Wei Guo, Ph.D.
Molecular basis of polarized exocytosis

215.898.9384 (tel)
215.898.8780 (fax)

Department of Biology, University of Pennsylvania

Erika L. F. Holzbaur, Ph.D.
Microtubule-based molecular motors

215.573.3257 (tel)
215.573.5851 (fax)

Department of Physiology, University of Pennsylvania

Christopher J. Janetopoulos, Ph.D.
Regulation of Cell Polarity during Migration and Cytokinesis

267.295.3118 (tel)
215.596.8710 (fax)

Department of Biological Sciences, University of the Sciences in Philadelphia

Paul A. Janmey, Ph.D.
Cytoskeletal mechanics & signaling

215.573.7380 (tel)
215.573.6815 (fax)

Department of Physiology, Institute for Medicine and Engineering, University of Pennsylvania

Roland G. Kallen, M.D., Ph.D.
Molecular characterization of ion channels

215.898.5184 (tel)
215.573.7058 (fax)

Biochemistry & Biophysics, University of Pennsylvania

Anna S. Kashina, Ph.D.
Physiological role of protein arginylation

215.746.0895 (tel)
215.573.5189 (fax)

Department of Animal Biology, University of Pennsylvania

Alan M. Kelly, B.Sc., B.V.Sc., Ph.D.
Development of neuromuscular specialization

215.898.8841 (tel)
215.573.8837 (fax)

Department of Pathobiology, School of Verterinary Medicine

Tejvir S. Khurana, M.D., Ph.D.
Neuromuscular disease & gene therapy

215.573.2640 (tel)
215.898.2653 (fax)

Department of Physiology, University of Pennsylvania

Karen E. Knudsen, Ph.D.
Integrins and Cadherins in muscle and cardiac development

610.645.2673 (tel)
610.645.2205 (fax)

Department of Cancer Biology, Thomas Jefferson University

Michael Lampson, Ph.D.
Chromosome segregation and cell division

215.746.3040 (tel)
215.898.8780 (fax)

Department of Biology, University of Pennsylvania

Jon Martin Lindstrom, Ph.D.
Nicotinic acelytcholine receptors

215.573.2859 (tel)
215.573.2858 (fax)

Neuroscience, University of Pennsylvania

Francis Luca, Ph.D.
Cell cycle, mitosis, cytokinesis

215.573.5664 (tel)
215.573.5188 (fax)

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania

Virginia Man-Yee Lee, Ph.D.
Biology of the neuronal cytoskeleton

215.662.6427 (tel)
215.349.5909 (fax)

Department of Pathology and Laboratory Medicine, University of Pennsylvania

Michael S. Marks, Ph.D.
Regulation and diseases of intracellular protein transport and organelle biogenesis

215-898-3204 (tel)

Department of Pathology and Laboratory Medicine, University of Pennsylvania

Kenneth B. Margulies, M.D.
Heart Failure and Transplant Research

215.707.4261 (tel)
215.707.5737 (fax)

Department of Medicine, Cardiovascular Division, University of Pennsylvania

Robert L. Mauck, Ph.D.
Musculoskeletal mechanobiology and tissue engineering

215.898.8653 (tel)
215.573.2133 (fax)

Department of Orthopaedic Surgery, Department of Bioengineering, University of Pennsylvania

Foteini Mourkioti, Ph.D.
Skeletal muscle and cardiac function in normal or diseased conditions

215.898.8214 (tel)
215.573.2133 (fax)

Department of Orthopaedic Surgery, University of Pennsylvania

John M. Murray, M.D., Ph.D.
Ultra-structure of molecular motors

215.898.3045 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

Vivianne T. Nachmias, Ph.D.
Regulation and control of the cytoskeleton

215.898.3162 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

E. Michael Ostap, Ph.D.
Biochemistry and cell biology of unconventional myosins

215.573.9758 (tel)
215.573.5851 (fax)

Department of Physiology, University of Pennsylvania

Michael S. Parmacek, M.D.
Muscle-specific gene expression

215.662.3140 (tel)
215.662.8017 (fax)

Division of Cardiovascular Medicine, School of Medicine, University of Pennsylvania

Jeffrey R. Peterson
Actin Cytoskeleton and Cell Motility

215.728.3568 (tel)
215.728.3574 (fax)

Fox Chase Cancer Center

Benjamin L. Prosser, Ph.D.
Calcium, redox, and mechano-signaling in heart

215.746.1488 (tel)

Department of Physiology, University of Pennsylvania

Elizabeth Rhoades, Ph.D.
Biophysics and biochemistry of intrinsically disordered proteins.

215.573.6477 (tel)

Department of Chemistry, University of Pennsylvania

Jeffrey Roizen, M.D., Ph.D., FAAP
Metabolism and action of vitamin D in muscle.

267.678.3597 (tel)

Department of Pediatrics, University of Pennsylvania
The Children’s Hospital of Philadelphia

Lawrence Rome, Ph.D.
Design and function of muscular systems for locomotion and sound productionCalcium, redox, and mechano-signaling in heart

215.898-9915 (tel)
215.898-8780 (fax)

Department of Biology, University of Pennsylvania

Neal A. Rubinstein, M.D., Ph.D.
Control of contractile protein expression

215.898.4162 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

Daniel Safer, Ph.D.
Regulation of actin assembly and cell motility

215.898.0045 (tel)
215.898.9871 (fax)

Department of Physiology, University of Pennsylvania

Patrick Seale, Ph.D.
Cell and Molecular Biology

215.573.8856 (tel)
215.898.5408 (fax)

Cell and Developmental Biology, University of Pennsylvania

Vivek B. Shenoy, Ph.D.
Understand the basic principles that control the behavior of both engineering and biological systems.

215.898.1558 (tel)

Penn Engineering, University of Pennsylvania

Henry Shuman, Ph.D.
Endocytosis, cytoskeleton and biophysics of molecular motors

215.898.3408 (tel)
215.898.5851 (fax)

Department of Physiology, University of Pennsylvania

Marion J. Siegman, Ph.D.
Control of smooth and catch muscle contraction

215.503.3975 (tel)
215.503.2073 (fax)

Department of Physiology, Thomas Jefferson University

Margaret M. Sleeper, VMD, BS
Inherited cardiomyopathies; Biochemical markers of cardiac disease; Real time 3D echocardiography

215.898.6439 (tel)
215.573.6232 (fax)

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania

Louis J. Soslowsky, Ph.D.
Rotator cuff injury and repair, Scarless regenerative tendon healing, Tendon structure-function relationships and injury-repair

215.898.8653 (tel)
215.573.2133 (fax)

Orthopaedic Surgery, McKay Orthopaedic Research Laboratory, University of Pennsylvania

Hansell H. Stedman, M.D.
Gene therapy for inherited muscle diseases

215.898.1432 (tel)
215.573.8606 (fax)

Department of Surgery, University of Pennsylvania

Tatyana M. Svitkina, Ph.D.
Mechanisms of cell motility and roles of the cytoskeleton

215.898.5736 (tel)
215.898.8780 (fax)

Department of Biology, University of Pennsylvania

H. Lee Sweeney, Ph.D.
Contractile protein function, human muscle diseases and gene therapy

352.273.9416 (tel)

Department of Pharmacology, University of Florida

Paul M. Titchenell, Ph.D.
Control of Muscle Metabolism by Insulin

215.573.1872 (tel)

Department of Physiology, Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania

Phong T. Tran, Ph.D.
Microtubule dynamics and cellular pattern formation

215.746.2755 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

David R. Trentham, FRS
Energy transduction and its regulation in muscle

+44 (0)20 8816 2082 (tel)
+44 (0)20 8906 4419 (fax)

NIMR/MRC

John W. Weisel, Ph.D.
Blood coagulation, fibrinolysis, and atherosclerosis

215.898.3573 (tel)
215.898.9871 (fax)

Cell and Developmental Biology, University of Pennsylvania

Rebecca G. Wells, M.D.
Mechanical and matrix factors in liver fibrosis

215.573.1860 (tel)
215.573.2024 (fax)

Department of Medicine (Gastroenterology), University of Pennsylvania

David F. Wilson, Ph.D.
Integration of metabolism; Oxidative phosphorylation; Neuroregulation

215.898.6382 (tel)
215.573.3787 (fax)

Biochemistry & Biophysics, University of Pennsylvania

Tim J. Yen, Ph.D.
Structure and function of mammalian centromeres and kinetochores

215.728.2590 (tel)
215.728.3616 (fax)

Cellular and Developmental Biology, Fox Chase Cancer Center

Christopher M. Yengo, Ph.D.
Motors Proteins and the Cytoskeleton, Protein Structure/Function and Dynamics, Enzyme Kinetics, Molecular Mechanisms of Myosin Based Motility.

717.531.8575 (tel)
717.531.8997 (fax)

Cellular and Molecular Physiology, Penn State Milton S. Hershey Medical Center