New Bolton Center, University of Pennsylvania School of Veterinary Medicine
New Bolton Center
382 West Street Road
Kennett Square, PA 19348
Phone: (610) 444-5800
Fax: (610) 925-8100
Position: Professor of Medicine
I investigated a neurologic syndrome which appeared familial in Morgan horses (a neuro-axonal dystrophy) and familial nuclear cataracts in this breed.
I have ongoing studies in equine myopathies, specifically intermittent exertional rhabdomyolysis and hyperkalemic periodic paralysis and myotonic dystrophy. Based on these studies phenytoin was introduced as prophylasis for the first condition. I have collaborated on some equine endocrinologic studies and introduced clinical use of pergolide for treating horses with pituitary tumors.
I have been involved with clinical application of skin testing and desensitization/hyposensitization of horses with allergic respiratory disease.
In the past, I published some papers on cytology (CSF and tracheal aspirates) in horses I am board certified in internal medicine and practice almost exclusively on horses.
- Beech J., Fletcher J.E., Johnston J. and Lizzo F. Effect of phenytoin on the clinical signs and in vitro muscle twitch characteristics of horses with chronic intermittent rhabdomyolysis and myotonia. Am J Vet Res 1988; 49 (12): 2130-2133.
- Beech J., Fletcher J.E., Tripolitis L., Lindborg S. Effects of phenytoin in two myotonic horses with hyperkalemic periodic paralysis. Muscle & Nerve, 1992; 15:932-936.
- Beech J and Haskins M. Genetic studies of neuroaxonal dystrophy in the Morgan Horse. Am J Vet Res 1987; 48:109-113.
- Beech J. Neuroaxonal dystrophy of the accessory cuneate nucleus in the horse. Vet Pathol 1984; 21:384-393.
- Fletcher J.E., Tripolitis L., Erwin K., Hanson S, Rosenberg H., Conti P.A., Beech J. Fatty acids modulate calcium-induced calcium release from skeletal muscle heavy sarcoplasmic reticulum fractions: implications for malignant hyperthermia. Biochemistry and Cell Biology 1990; 68:1195-1201.