Penn Medicine
   

Members

[ View by Alphabetical Order ]

CELL MIGRATION AND INTRACELLULAR TRANSPORT

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Erfei Bi
Cell polarity and the control of cytokinesis
215.573.6676
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Lynne Cassimeris
Regulation of microtubule assembly
610.758.6275
610.758.4004
Department of Biological Sciences, Lehigh University
Dr. Camille DiLullo
Integrins and myofibrillar cytoskeleton
215.871.6542
215.871.6540
Department of Anatomy, Philadelphia College of Osteopathic Medicine
Dr. Wei Guo
Molecular basis of polarized exocytosis
215.898.9384
215.898.8780
Biology, University of Pennsylvania
Dr. Erika L. F. Holzbaur
Microtubule-based molecular motors
215.573.3257
215.573.5851
Department of Physiology, University of Pennsylvania
Dr. Paul Janmey
Cytoskeletal mechanics & signaling
215.573.7380
215.573.6815
Physiology, Institute for Medicine and Engineering, University of Pennsylvania
Dr. Karen A. Knudsen
Integrins and Cadherins in muscle and cardiac development
610.645.2673
610.645.2205
Lankenau Institute for Medical Research
Dr. Frank Luca
Cell cycle, mitosis, cytokinesis
215.573.5664
215.573.5188
Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania
Dr. John M. Murray
Ultra-structure of molecular motors
215.898.3045
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Vivianne T. Nachmias
Regulation and control of the cytoskeleton
215.898.3162
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. E. Michael Ostap
Biochemistry and cell biology of unconventional myosins
E-mail
215.573.9758
215.573.1171
Department of Physiology, University of Pennsylvania
Dr. Daniel Safer
Regulation of actin assembly and cell motility
215.898.0045
215.898.9871
Department of Physiology, University of Pennsylvania
Dr. Jean M. Sanger
Actin-based cell motility
315.464.8551 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger
Assembly and function of cytoskeletal proteins
315.464.5120 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Henry Shuman
Endocytosis, cytoskeleton and biophysics of molecular motors
215.898.3408
215.898.5851
Department of Physiology, University of Pennsylvania
Dr. H. Lee Sweeney
Contractile protein function, human muscle diseases and gene therapy
215.898.8727
215.573.2273
Department of Physiology, University of Pennsylvania
Dr. Annemarie Weber
Regulation of actin filament assembly and disassembly
215.898.6392
215.898.4217
Biochemistry & Biophysics, University of Pennsylvania
Dr. John W. Weisel
Blood coagulation, fibrinolysis, and atherosclerosis
215.898.3573
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Tim J. Yen
Structure and function of mammalian centromeres and kinetochores
215.728.2590
215.728.3616
Cellular and Developmental Biology, Fox Chase Cancer Center
Dr. Sally H. Zigmond
Cell migration and chemotaxis
215.898.4559
215.898.8780
Department of Biology, University of Pennsylvania

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MECHANISM AND REGULATION OF MUSCLE CONTRACTION

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Robert Barsotti
Smooth and cardiac muscle physiology
215.893.2368 Department of Physiology,
Thomas Jefferson University
Dr. Stephen M. Baylor
E-C coupling in skeletal muscle
215.898.5559
215.573.5851
Department of Physiology, University of Pennsylvania
Dr. Thomas M. Butler
Control of smooth and catch muscle contraction
215.503.6583
215.503.2073
Department of Physiology, Thomas Jefferson University
Dr. Samuel K. Chacko
Regulation of smooth muscle
215.898.5755
215.898.0719
Department of Pathobiology, School of Veterinary Medicine
Dr. Clara Franzini-Armstrong
Ultrastructure of striated muscle
215.898.3345
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Yale E. Goldman
Molecular mechanism of muscle contraction
215.898.4017
215.898.2653
Physiology, University of Pennsylvania
Dr. Michael M. Grunstein
Pulmonary smooth muscle and asthma
215.590.3497
215.590.3500
Division of Pulmonary Medicine, Children's Hospital of Philadelphia
Dr. Roland G. Kallen
Molecular characterization of ion channels
215.898.5184
215.573.7058
Biochemistry & Biophysics, University of Pennsylvania
Dr. E. Michael Ostap
Biochemistry and cell biology of unconventional myosins
E-mail
215.573.9758
215.573.1171
Department of Physiology, University of Pennsylvania
Dr. Michael S. Parmacek
Muscle-specific gene expression
215.662.3140
215.662.8017
Division of Cardiovascular Medicine, School of Medicine, University of Pennsylvania
Dr. Lawrence C. Rome
Muscle mechanics and locomotion
215.898.9915
215.898.8780
Department of Biology, University of Pennsylvania
Dr. Neal A. Rubinstein
Control of contractile protein expression
215.898.4162
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Daniel Safer
Regulation of actin assembly and cell motility
215.898.0045
215.898.9871
Department of Physiology, University of Pennsylvania
Dr. Joseph B. Shrager
Respiratory muscle pathology; Muscular dystrophy
215.662.4767
215.349.5798
Surgery, University of Pennsylvania
Dr. Henry Shuman
Endocytosis, cytoskeleton and biophysics of molecular motors
215.898.3408
215.898.5851
Department of Physiology, University of Pennsylvania
Dr. Marion J. Siegman
Control of smooth and catch muscle contraction
215.503.3975
215.503.2073
Department of Physiology, Thomas Jefferson University
Dr. Hansell H. Stedman
Gene therapy for inherited muscle diseases
215.898.1432
215.573.8606
Department of Surgery, University of Pennsylvania
Dr. H. Lee Sweeney
Contractile protein function, human muscle diseases and gene therapy
215.898.8727
215.573.2273
Department of Physiology, University of Pennsylvania
Dr. David R. Trentham
Energy transduction and its regulation in muscle
+44 (0)20 8816 2082
+44 (0)20 8906 4419
NIMR/MRC

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STRUCTURE/FUNCTION STUDIES OF MOLECULAR MOTORS

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Clara Franzini-Armstrong
Ultrastructure of striated muscle
215.898.3345
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Yale E. Goldman
Molecular mechanism of muscle contraction
215.898.4017
215.898.2653
Physiology, University of Pennsylvania
Dr. Erika L. F. Holzbaur
Microtubule-based molecular motors
215.573.3257
215.573.5851
Department of Physiology, University of Pennsylvania
Dr. John M. Murray
Ultra-structure of molecular motors
215.898.3045
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. E. Michael Ostap
Biochemistry and cell biology of unconventional myosins
E-mail
215.573.9758
215.573.1171
Department of Physiology, University of Pennsylvania
Dr. Daniel Safer
Regulation of actin assembly and cell motility
215.898.0045
215.898.9871
Department of Physiology, University of Pennsylvania
Dr. Henry Shuman
Endocytosis, cytoskeleton and biophysics of molecular motors
215.898.3408
215.898.5851
Department of Physiology, University of Pennsylvania
Dr. H. Lee Sweeney
Contractile protein function, human muscle diseases and gene therapy
215.898.8727
215.573.2273
Department of Physiology, University of Pennsylvania
Dr. Tim J. Yen
Structure and function of mammalian centromeres and kinetochores
215.728.2590
215.728.3616
Cellular and Developmental Biology, Fox Chase Cancer Center

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CHROMOSOME SEGREGATION AND CELL DIVISION

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Erfei Bi
Cell polarity and the control of cytokinesis
215.573.6676
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Lynne Cassimeris
Regulation of microtubule assembly
610.758.6275
610.758.4004
Department of Biological Sciences, Lehigh University
Dr. Erika L. F. Holzbaur
Microtubule-based molecular motors
215.573.3257
215.573.5851
Department of Physiology, University of Pennsylvania
Dr. Frank Luca
Cell cycle, mitosis, cytokinesis
215.573.5664
215.573.5188
Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania
Dr. John M. Murray
Ultra-structure of molecular motors
215.898.3045
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Vivianne T. Nachmias
Regulation and control of the cytoskeleton
215.898.3162
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Jean M. Sanger
Actin-based cell motility
315.464.8551 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger
Assembly and function of cytoskeletal proteins
315.464.5120 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Tim J. Yen
Structure and function of mammalian centromeres and kinetochores
215.728.2590
215.728.3616
Cellular and Developmental Biology, Fox Chase Cancer Center

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GENE THERAPY AND NEUROMUSCULAR DISEASE

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Rita J. Balice-Gordon
Developmental neuroscience
215.898.1037
215.573.9122
Neuroscience, University of Pennsylvania
Dr. Frederic G. Barr
Genetics of chromosomal rearrangements in sarcoma
215.898.0884
215.898.4227
Pathology, University of Pennsylvania
Dr. Jill Beech
Equine myopathies
610.444.5800
610.925.8100
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania
Dr. Carsten Bönnemann
Molecular genetics of congenital and limb-girdle muscular dystrophies
215.590.7490
215.590.3709
Division of Neurology, Children's Hospital of Philadelphia
Dr. Jonathan A. Epstein
Heart and muscle development
215.898.8731
215.573.2094
Department of Medicine, University of Pennsylvania
Dr. Michael M. Grunstein
Pulmonary smooth muscle and asthma
215.590.3497
215.590.3500
Division of Pulmonary Medicine, Children's Hospital of Philadelphia
Dr. Roland G. Kallen
Molecular characterization of ion channels
215.898.5184
215.573.7058
Biochemistry & Biophysics, University of Pennsylvania
Dr. Tejvir Khurana
Neuromuscular disease & gene therapy
215.573.2640
215.898.2653
Department of Physiology, University of Pennsylvania
Dr. Jon M. Lindstrom
Nicotinic acelytcholine receptors
215.573.2859
215.573.2858
Neuroscience, University of Pennsylvania
Dr. Virginia Man-Yee Lee
Biology of the neuronal cytoskeleton
215.662.6427
215.349.5909
Department of Pathology and Laboratory Medicine, University of Pennsylvania
Dr. Joseph B. Shrager
Respiratory muscle pathology; Muscular dystrophy
215.662.4767
215.349.5798
Surgery, University of Pennsylvania
Dr. Hansell H. Stedman
Gene therapy for inherited muscle diseases
215.898.1432
215.573.8606
Department of Surgery, University of Pennsylvania
Dr. H. Lee Sweeney
Contractile protein function, human muscle diseases and gene therapy
215.898.8727
215.573.2273
Department of Physiology, University of Pennsylvania
Dr. David F. Wilson
Integration of metabolism; Oxidative phosphorylation; Neuroregulation
215.898.6382
215.573.3787
Biochemistry & Biophysics, University of Pennsylvania

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MUSCLE CELL DEVELOPMENT AND MYOFIBRIL ASSEMBLY

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Rita J. Balice-Gordon
Developmental neuroscience
215.898.1037
215.573.9122
Neuroscience, University of Pennsylvania
Dr. Frederic G. Barr
Genetics of chromosomal rearrangements in sarcoma
215.898.0884
215.898.4227
Pathology, University of Pennsylvania
Dr. Erfei Bi
Cell polarity and the control of cytokinesis
215.573.6676
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Carsten Bönnemann
Molecular genetics of congenital and limb-girdle muscular dystrophies
215.590.7490
215.590.3709
Division of Neurology, Children's Hospital of Philadelphia
Dr. Margaret M. Chou
G-Protein & cell transformations
215.573.4126
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Camille DiLullo
Integrins and myofibrillar cytoskeleton
215.871.6542
215.871.6540
Department of Anatomy, Philadelphia College of Osteopathic Medicine
Dr. Dennis E. Discher
Cell and molecular mechanics
215.898.4809
215.573.2093
Chemical /Biomolecular Engineering and Bioengineering, University of Pennsylvania
Dr. Jonathan A. Epstein
Heart and muscle development
215.898.8731
215.573.2094
Department of Medicine, University of Pennsylvania
Dr. Howard Holtzer
Assembly of striated myofibrils
215.898.8089
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Alan M. Kelly
Development of neuromuscular specialization
215.898.8841
215.573.8837
Department of Pathobiology, School of Verterinary Medicine
Dr. Karen A. Knudsen
Integrins and Cadherins in muscle and cardiac development
610.645.2673
610.645.2205
Lankenau Institute for Medical Research
Dr. Michael S. Parmacek
Muscle-specific gene expression
215.662.3140
215.662.8017
Division of Cardiovascular Medicine, School of Medicine, University of Pennsylvania
Dr. Neal A. Rubinstein
Control of contractile protein expression
215.898.4162
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Jean M. Sanger
Actin-based cell motility
315.464.8551 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger
Assembly and function of cytoskeletal proteins
315.464.5120 Cell and Developmental Biology, SUNY Upstate Medical University
Dr. H. Lee Sweeney
Contractile protein function, human muscle diseases and gene therapy
215.898.8727
215.573.2273
Department of Physiology, University of Pennsylvania
Dr. John W. Weisel
Blood coagulation, fibrinolysis, and atherosclerosis
215.898.3573
215.898.9871
Cell and Developmental Biology, University of Pennsylvania

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ADVANCED TECHNOLOGICAL DEVELOPMENT

Name/Research Interest
E-mail
Phone/Fax Department
Dr. Stephen M. Baylor
E-C coupling in skeletal muscle
215.898.5559
215.573.5851
Department of Physiology, University of Pennsylvania
Dr. Dennis E. Discher
Cell and molecular mechanics
215.898.4809
215.573.2093
Chemical /Biomolecular Engineering and Bioengineering, University of Pennsylvania
Dr. Yale E. Goldman
Molecular mechanism of muscle contraction
215.898.4017
215.898.2653
Physiology, University of Pennsylvania
Dr. Wei Guo
Molecular basis of polarized exocytosis
215.898.9384
215.898.8780
Biology, University of Pennsylvania
Dr. Paul Janmey
Cytoskeletal mechanics & signaling
215.573.7380
215.573.6815
Physiology, Institute for Medicine and Engineering, University of Pennsylvania
Dr. John M. Murray
Ultra-structure of molecular motors
215.898.3045
215.898.9871
Cell and Developmental Biology, University of Pennsylvania
Dr. Henry Shuman
Endocytosis, cytoskeleton and biophysics of molecular motors
215.898.3408
215.898.5851
Department of Physiology, University of Pennsylvania
Dr. David R. Trentham
Energy transduction and its regulation in muscle
+44 (0)20 8816 2082
+44 (0)20 8906 4419
NIMR/MRC
Dr. David F. Wilson
Integration of metabolism; Oxidative phosphorylation; Neuroregulation
215.898.6382
215.573.3787
Biochemistry & Biophysics, University of Pennsylvania

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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653