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CELL MIGRATION AND INTRACELLULAR TRANSPORT

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Erfei Bi Cell polarity and the control of cytokinesis	E-mail	215.573.6676 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Lynne Cassimeris Regulation of microtubule assembly	E-mail	610.758.6275 610.758.4004	Department of Biological Sciences, Lehigh University
Dr. Camille DiLullo Integrins and myofibrillar cytoskeleton	E-mail	215.871.6542 215.871.6540	Department of Anatomy, Philadelphia College of Osteopathic Medicine
Dr. Wei Guo Molecular basis of polarized exocytosis	E-mail	215.898.9384 215.898.8780	Biology, University of Pennsylvania
Dr. Erika L. F. Holzbaur Microtubule-based molecular motors	E-mail	215.573.3257 215.573.5851	Department of Physiology, University of Pennsylvania
Dr. Paul Janmey Cytoskeletal mechanics & signaling	E-mail	215.573.7380 215.573.6815	Physiology, Institute for Medicine and Engineering, University of Pennsylvania
Dr. Karen A. Knudsen Integrins and Cadherins in muscle and cardiac development	E-mail	610.645.2673 610.645.2205	Lankenau Institute for Medical Research
Dr. Frank Luca Cell cycle, mitosis, cytokinesis	E-mail	215.573.5664 215.573.5188	Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania
Dr. John M. Murray Ultra-structure of molecular motors	E-mail	215.898.3045 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Vivianne T. Nachmias Regulation and control of the cytoskeleton	E-mail	215.898.3162 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. E. Michael Ostap Biochemistry and cell biology of unconventional myosins	E-mail	215.573.9758 215.573.1171	Department of Physiology, University of Pennsylvania
Dr. Daniel Safer Regulation of actin assembly and cell motility	E-mail	215.898.0045 215.898.9871	Department of Physiology, University of Pennsylvania
Dr. Jean M. Sanger Actin-based cell motility	E-mail	315.464.8551	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger Assembly and function of cytoskeletal proteins	E-mail	315.464.5120	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Henry Shuman Endocytosis, cytoskeleton and biophysics of molecular motors	E-mail	215.898.3408 215.898.5851	Department of Physiology, University of Pennsylvania
Dr. H. Lee Sweeney Contractile protein function, human muscle diseases and gene therapy	E-mail	215.898.8727 215.573.2273	Department of Physiology, University of Pennsylvania
Dr. Annemarie Weber Regulation of actin filament assembly and disassembly	E-mail	215.898.6392 215.898.4217	Biochemistry & Biophysics, University of Pennsylvania
Dr. John W. Weisel Blood coagulation, fibrinolysis, and atherosclerosis	E-mail	215.898.3573 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Tim J. Yen Structure and function of mammalian centromeres and kinetochores	E-mail	215.728.2590 215.728.3616	Cellular and Developmental Biology, Fox Chase Cancer Center
Dr. Sally H. Zigmond Cell migration and chemotaxis	E-mail	215.898.4559 215.898.8780	Department of Biology, University of Pennsylvania

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MECHANISM AND REGULATION OF MUSCLE CONTRACTION

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Robert Barsotti Smooth and cardiac muscle physiology	E-mail	215.893.2368	Department of Physiology, Thomas Jefferson University
Dr. Stephen M. Baylor E-C coupling in skeletal muscle	E-mail	215.898.5559 215.573.5851	Department of Physiology, University of Pennsylvania
Dr. Thomas M. Butler Control of smooth and catch muscle contraction	E-mail	215.503.6583 215.503.2073	Department of Physiology, Thomas Jefferson University
Dr. Samuel K. Chacko Regulation of smooth muscle	E-mail	215.898.5755 215.898.0719	Department of Pathobiology, School of Veterinary Medicine
Dr. Clara Franzini-Armstrong Ultrastructure of striated muscle	E-mail	215.898.3345 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Yale E. Goldman Molecular mechanism of muscle contraction	E-mail	215.898.4017 215.898.2653	Physiology, University of Pennsylvania
Dr. Michael M. Grunstein Pulmonary smooth muscle and asthma	E-mail	215.590.3497 215.590.3500	Division of Pulmonary Medicine, Children's Hospital of Philadelphia
Dr. Roland G. Kallen Molecular characterization of ion channels	E-mail	215.898.5184 215.573.7058	Biochemistry & Biophysics, University of Pennsylvania
Dr. E. Michael Ostap Biochemistry and cell biology of unconventional myosins	E-mail	215.573.9758 215.573.1171	Department of Physiology, University of Pennsylvania
Dr. Michael S. Parmacek Muscle-specific gene expression	E-mail	215.662.3140 215.662.8017	Division of Cardiovascular Medicine, School of Medicine, University of Pennsylvania
Dr. Lawrence C. Rome Muscle mechanics and locomotion	E-mail	215.898.9915 215.898.8780	Department of Biology, University of Pennsylvania
Dr. Neal A. Rubinstein Control of contractile protein expression	E-mail	215.898.4162 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Daniel Safer Regulation of actin assembly and cell motility	E-mail	215.898.0045 215.898.9871	Department of Physiology, University of Pennsylvania
Dr. Joseph B. Shrager Respiratory muscle pathology; Muscular dystrophy	E-mail	215.662.4767 215.349.5798	Surgery, University of Pennsylvania
Dr. Henry Shuman Endocytosis, cytoskeleton and biophysics of molecular motors	E-mail	215.898.3408 215.898.5851	Department of Physiology, University of Pennsylvania
Dr. Marion J. Siegman Control of smooth and catch muscle contraction	E-mail	215.503.3975 215.503.2073	Department of Physiology, Thomas Jefferson University
Dr. Hansell H. Stedman Gene therapy for inherited muscle diseases	E-mail	215.898.1432 215.573.8606	Department of Surgery, University of Pennsylvania
Dr. H. Lee Sweeney Contractile protein function, human muscle diseases and gene therapy	E-mail	215.898.8727 215.573.2273	Department of Physiology, University of Pennsylvania
Dr. David R. Trentham Energy transduction and its regulation in muscle	E-mail	+44 (0)20 8816 2082 +44 (0)20 8906 4419	NIMR/MRC

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STRUCTURE/FUNCTION STUDIES OF MOLECULAR MOTORS

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Clara Franzini-Armstrong Ultrastructure of striated muscle	E-mail	215.898.3345 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Yale E. Goldman Molecular mechanism of muscle contraction	E-mail	215.898.4017 215.898.2653	Physiology, University of Pennsylvania
Dr. Erika L. F. Holzbaur Microtubule-based molecular motors	E-mail	215.573.3257 215.573.5851	Department of Physiology, University of Pennsylvania
Dr. John M. Murray Ultra-structure of molecular motors	E-mail	215.898.3045 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. E. Michael Ostap Biochemistry and cell biology of unconventional myosins	E-mail	215.573.9758 215.573.1171	Department of Physiology, University of Pennsylvania
Dr. Daniel Safer Regulation of actin assembly and cell motility	E-mail	215.898.0045 215.898.9871	Department of Physiology, University of Pennsylvania
Dr. Henry Shuman Endocytosis, cytoskeleton and biophysics of molecular motors	E-mail	215.898.3408 215.898.5851	Department of Physiology, University of Pennsylvania
Dr. H. Lee Sweeney Contractile protein function, human muscle diseases and gene therapy	E-mail	215.898.8727 215.573.2273	Department of Physiology, University of Pennsylvania
Dr. Tim J. Yen Structure and function of mammalian centromeres and kinetochores	E-mail	215.728.2590 215.728.3616	Cellular and Developmental Biology, Fox Chase Cancer Center

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CHROMOSOME SEGREGATION AND CELL DIVISION

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Erfei Bi Cell polarity and the control of cytokinesis	E-mail	215.573.6676 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Lynne Cassimeris Regulation of microtubule assembly	E-mail	610.758.6275 610.758.4004	Department of Biological Sciences, Lehigh University
Dr. Erika L. F. Holzbaur Microtubule-based molecular motors	E-mail	215.573.3257 215.573.5851	Department of Physiology, University of Pennsylvania
Dr. Frank Luca Cell cycle, mitosis, cytokinesis	E-mail	215.573.5664 215.573.5188	Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania
Dr. John M. Murray Ultra-structure of molecular motors	E-mail	215.898.3045 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Vivianne T. Nachmias Regulation and control of the cytoskeleton	E-mail	215.898.3162 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Jean M. Sanger Actin-based cell motility	E-mail	315.464.8551	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger Assembly and function of cytoskeletal proteins	E-mail	315.464.5120	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Tim J. Yen Structure and function of mammalian centromeres and kinetochores	E-mail	215.728.2590 215.728.3616	Cellular and Developmental Biology, Fox Chase Cancer Center

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GENE THERAPY AND NEUROMUSCULAR DISEASE

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Rita J. Balice-Gordon Developmental neuroscience	E-mail	215.898.1037 215.573.9122	Neuroscience, University of Pennsylvania
Dr. Frederic G. Barr Genetics of chromosomal rearrangements in sarcoma	E-mail	215.898.0884 215.898.4227	Pathology, University of Pennsylvania
Dr. Jill Beech Equine myopathies	E-mail	610.444.5800 610.925.8100	Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania
Dr. Carsten Bönnemann Molecular genetics of congenital and limb-girdle muscular dystrophies	E-mail	215.590.7490 215.590.3709	Division of Neurology, Children's Hospital of Philadelphia
Dr. Jonathan A. Epstein Heart and muscle development	E-mail	215.898.8731 215.573.2094	Department of Medicine, University of Pennsylvania
Dr. Michael M. Grunstein Pulmonary smooth muscle and asthma	E-mail	215.590.3497 215.590.3500	Division of Pulmonary Medicine, Children's Hospital of Philadelphia
Dr. Roland G. Kallen Molecular characterization of ion channels	E-mail	215.898.5184 215.573.7058	Biochemistry & Biophysics, University of Pennsylvania
Dr. Tejvir Khurana Neuromuscular disease & gene therapy	E-mail	215.573.2640 215.898.2653	Department of Physiology, University of Pennsylvania
Dr. Jon M. Lindstrom Nicotinic acelytcholine receptors	E-mail	215.573.2859 215.573.2858	Neuroscience, University of Pennsylvania
Dr. Virginia Man-Yee Lee Biology of the neuronal cytoskeleton	E-mail	215.662.6427 215.349.5909	Department of Pathology and Laboratory Medicine, University of Pennsylvania
Dr. Joseph B. Shrager Respiratory muscle pathology; Muscular dystrophy	E-mail	215.662.4767 215.349.5798	Surgery, University of Pennsylvania
Dr. Hansell H. Stedman Gene therapy for inherited muscle diseases	E-mail	215.898.1432 215.573.8606	Department of Surgery, University of Pennsylvania
Dr. H. Lee Sweeney Contractile protein function, human muscle diseases and gene therapy	E-mail	215.898.8727 215.573.2273	Department of Physiology, University of Pennsylvania
Dr. David F. Wilson Integration of metabolism; Oxidative phosphorylation; Neuroregulation	E-mail	215.898.6382 215.573.3787	Biochemistry & Biophysics, University of Pennsylvania

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MUSCLE CELL DEVELOPMENT AND MYOFIBRIL ASSEMBLY

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Rita J. Balice-Gordon Developmental neuroscience	E-mail	215.898.1037 215.573.9122	Neuroscience, University of Pennsylvania
Dr. Frederic G. Barr Genetics of chromosomal rearrangements in sarcoma	E-mail	215.898.0884 215.898.4227	Pathology, University of Pennsylvania
Dr. Erfei Bi Cell polarity and the control of cytokinesis	E-mail	215.573.6676 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Carsten Bönnemann Molecular genetics of congenital and limb-girdle muscular dystrophies	E-mail	215.590.7490 215.590.3709	Division of Neurology, Children's Hospital of Philadelphia
Dr. Margaret M. Chou G-Protein & cell transformations	E-mail	215.573.4126 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Camille DiLullo Integrins and myofibrillar cytoskeleton	E-mail	215.871.6542 215.871.6540	Department of Anatomy, Philadelphia College of Osteopathic Medicine
Dr. Dennis E. Discher Cell and molecular mechanics	E-mail	215.898.4809 215.573.2093	Chemical /Biomolecular Engineering and Bioengineering, University of Pennsylvania
Dr. Jonathan A. Epstein Heart and muscle development	E-mail	215.898.8731 215.573.2094	Department of Medicine, University of Pennsylvania
Dr. Howard Holtzer Assembly of striated myofibrils	E-mail	215.898.8089 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Alan M. Kelly Development of neuromuscular specialization	E-mail	215.898.8841 215.573.8837	Department of Pathobiology, School of Verterinary Medicine
Dr. Karen A. Knudsen Integrins and Cadherins in muscle and cardiac development	E-mail	610.645.2673 610.645.2205	Lankenau Institute for Medical Research
Dr. Michael S. Parmacek Muscle-specific gene expression	E-mail	215.662.3140 215.662.8017	Division of Cardiovascular Medicine, School of Medicine, University of Pennsylvania
Dr. Neal A. Rubinstein Control of contractile protein expression	E-mail	215.898.4162 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Jean M. Sanger Actin-based cell motility	E-mail	315.464.8551	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. Joseph W. Sanger Assembly and function of cytoskeletal proteins	E-mail	315.464.5120	Cell and Developmental Biology, SUNY Upstate Medical University
Dr. H. Lee Sweeney Contractile protein function, human muscle diseases and gene therapy	E-mail	215.898.8727 215.573.2273	Department of Physiology, University of Pennsylvania
Dr. John W. Weisel Blood coagulation, fibrinolysis, and atherosclerosis	E-mail	215.898.3573 215.898.9871	Cell and Developmental Biology, University of Pennsylvania

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ADVANCED TECHNOLOGICAL DEVELOPMENT

Name/Research Interest	E-mail	Phone/Fax	Department
Dr. Stephen M. Baylor E-C coupling in skeletal muscle	E-mail	215.898.5559 215.573.5851	Department of Physiology, University of Pennsylvania
Dr. Dennis E. Discher Cell and molecular mechanics	E-mail	215.898.4809 215.573.2093	Chemical /Biomolecular Engineering and Bioengineering, University of Pennsylvania
Dr. Yale E. Goldman Molecular mechanism of muscle contraction	E-mail	215.898.4017 215.898.2653	Physiology, University of Pennsylvania
Dr. Wei Guo Molecular basis of polarized exocytosis	E-mail	215.898.9384 215.898.8780	Biology, University of Pennsylvania
Dr. Paul Janmey Cytoskeletal mechanics & signaling	E-mail	215.573.7380 215.573.6815	Physiology, Institute for Medicine and Engineering, University of Pennsylvania
Dr. John M. Murray Ultra-structure of molecular motors	E-mail	215.898.3045 215.898.9871	Cell and Developmental Biology, University of Pennsylvania
Dr. Henry Shuman Endocytosis, cytoskeleton and biophysics of molecular motors	E-mail	215.898.3408 215.898.5851	Department of Physiology, University of Pennsylvania
Dr. David R. Trentham Energy transduction and its regulation in muscle	E-mail	+44 (0)20 8816 2082 +44 (0)20 8906 4419	NIMR/MRC
Dr. David F. Wilson Integration of metabolism; Oxidative phosphorylation; Neuroregulation	E-mail	215.898.6382 215.573.3787	Biochemistry & Biophysics, University of Pennsylvania

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Pennsylvania Muscle Institute
Perelman School of Medicine

University of Pennsylvania
Director: E. Michael Ostap, Ph.D.
700A Clinical Research Building

Philadelphia, PA 19104-6085

Phone: (215) 573-9758

Fax: (215) 898-2653