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Dr. Michael Ostap is the featured Biophysical Journal Editor. Scroll down to see interview. HERE
Validation of multicenter protocol examining imaging of DMD patients. HERE
Dr. Dominguez's Lab shows how Rickettsia hijacks the actin cytoskeleton. HERE
PMI Labs show how molecular motors move growth factors in living cells. HERE
Dr. Grischchuk measures the force of microtubule depolymerization HERE
See Dr. Discher's Science article on Nanoparticle Delivery HERE
See the recent Penn News article highlighting recent work from Dr. Yale E. Goldman’s Lab HERE

Congratulations to the winners of the 2013 PMI Symposium Poster Competition- Adam Zwolak, PhD and Stephen Norris
2013 PMI Retreat and Symposium
Cytoskeletal Regulation
February 1, 2013
- Congratulations to Dr. Jacob Lazarus for receiving his Ph.D. under Erika Holzbaur, Ph.D., Pennsylvania Muscle Institute!
- We note with deep regret the passing of Prof. Annemarie Weber, a treasured and generous colleague and a pioneer in the field of muscle research. Click here to read about Dr. Weber’s scientific contributions.
- Congratulations to Betsy Buechler for receiving a pre-doctoral fellowhip from the American Heart Association
- Congratulations to Tali Dadosh and Anatoly Zaytsev for receiving poster presentation awards at the PMI/NBIC Symposium.
- Thanks to all who participated in the 2012 PMI/NBIC Symposium. Click here for Symposium schedule.
- Congratulations to Dr. Jennine Dawicki McKenna for receiving her Ph.D. under E. Michael Ostap, Ph.D., Pennsylvania Muscle Institute!
- Congratulations to Dr. Dennis Discher for being named the Robert D. Bent Professor of Chemical and Biomolecular Engineering. Details here.
- Thanks to all who participated in the 2011 PMI/Wellstone Mini Symposium. Click here for Symposium schedule.
- Thanks to all who participated in the 2011 PMI/IDOM Muscle and Metabolism Retreat and Symposium. Click here for the symposium schedule. The honorary lecturers at the symposium were as follows:
Robert E. Davies Honorary Lectures
Joseph A. Baur, Ph.D.
Perelman School of Medicine at the University of Pennsylvania
Mimicking Caloric Restriction in Muscle
Alfred L. Goldberg, Ph.D
Harvard University
Molecular Mechanisms of Muscle Atrophy
H. Lee Sweeney
Perelman School of Medicine at the University of Pennsylvania
Myostatin and IGF-I Interactions and Implications for Treating both Muscular Dystrophies and Sarcopenia
Andrew P. Somlyo Honorary Lectures
Elisabeth R. Barton, Ph.D.
University of Pennsylvania School of Dental Medicine
Importance of Muscle IGF-I for Organismal Growth
Vittorio Sartorelli, M.D.
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health
Epigenetics of Skeletal Myogenesis
Deborah M. Muoio, Ph.D.
Duke University Medical Center
Mitochondrial Stress and Insulin Action in Muscle
- Congratulations to Dr. Clara Franzini-Armstrong for her election to the Accademia dei Lincei, which is a premier Italian academy of science, founded in 1603. The academy has a rich history, including counting Galileo Galilei as a member. The academy published Galileo’s works and supported him throughout his disputes with the church. Giovanni Faber, who coined the name “microscope,” was also a member, as well as noted mineralogist Marco Franzini (Clara’s twin brother for whom the mineral Franzinite was named). Dr. Franzini-Armstrong is also a member of the National Academy of Sciences (USA) and the Royal Society (UK).
- New work from Dr. Tejvir Khurana’s laboratory has identified a gene that negatively regulates muscle endurance. The first author of this paper is Dr. Emidio Pistilli, an alumnus of our T32-supported training program in Muscle Biology and Muscle Disease. See Penn press release here, comment in Science here, and the complete paper here.
- Congratulations to Meredith Wilson (Holzbaur Laboratory) and Dr. David Kast (Dominguez Laboratory) for being appointed to the PMI training grant.
- See article in The Scientist featuring work from the Goldman and Holzbaur Labs, here.
- Congratulations to Dr. Roman Gorelik for receiving his Ph.D. under Dr. Tatyana Svitkina, Department of Biology. "Actin-independent mechanisms of targeting formin mDia2 to the plasma membrane"
- Congratulations to Dr. John Lewis for successfully
defending his Ph.D. thesis, “Examining the coupling of the mechanical and chemical functions of myosin family members using single molecule and bulk solution techniques.” John was advised
by Dr. Yale E. Goldman/Dr. E. Michael Ostap. and was a member of the Cell and Molecular
Biology Graduate program.
- See highlights of Dr. Erfei Bi’s exciting new study on the role of myosin in cell division here, and see the complete paper here.
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