Penn Medicine

The Pennsylvania Muscle Institute

Force Sensing: Mechanobiology from Molecules to Tissues
Perelman School of Medicine at the University of Pennsylvania

October 28, 2013


Directions HERE   Lodgings HERE
Location Smilow Center for Translational Research
3400 Civic Center Boulevard
Philadelphia, PA 19104
Directions can be found:

9:00-9:10 E. Michael Ostap, Ph.D.- Director, Pennsylvnaia Muscle Institute, Universiyt of Pennsylvania


9:10-10:00 Jay T. Groves, Ph.D.
Professor of Chemistry
University of California, Berkeley
"The mechanics of signal transduction in cell membranes down to the single molecule level"
10:00-10:20 Ekaterina L. Grishchuk, Ph.D.
Assistant Professor of Physiology
University of Pennsylvania
"Ring coupler for a microtubule depolymerization motor”
Michael J. Greenberg, Ph.D. (Ostap Lab) - Post-Doctoral Researcher, University of Pennsylvania
“Mechanical and biochemical insights into the mechanism of myosin-I force sensing”
10:35-10:50 Hossein Ahmadzadeh (Shenoy Lab) - Graduate Student, University of Pennsylvania
“Tau protein viscoelastic response is the central mechanism behind microtubule breaking during traumatic axonal injury”

10:50-11:05 Coffee Break / Posters


Martin A. Schwartz, Ph.D.
Robert W. Berliner Professor of Medicine and Professor of Cell Biology
Yale University
“Mechanisms of fluid shear stress sensing by endothelial cells”
11:55-12:15 Robert L. Mauck, Ph.D.
Associate Professor of Orthopaedic Surgery & Bioengineering
University of Pennsylvania
"Dynamic alterations in stem cell nuclear structure and mechanobiology with mechanical perturbation"
12:15-12:30 Joe Swift, Ph.D. (Discher Lab) – Post-Doctoral Researcher, University of Pennsylvania
“Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation”
12:30-12:45 Keeley L. Miu (Assoian Lab) - Graduate Student, University of Pennsylvania
“Crosstalk between cell-matrix and cell-cell adhesions in mechanosensitive cell cycling”
12:45-2:00 Lunch and Posters


2:00-2:20 Paul A. Janmey, Ph.D.
Professor of Physiology and Professor of Bioengineering
University of Pennsylvania
“Effects of hyaluronic acid on integrin-mediated mechanotransduction”
2:20-2:40 Benjamin L. Prosser, Ph.D.
Assistant Professor of Physiology
University of Maryland
"Pulling on the heart strings: mechano-chemo transduction in heart"
2:40-2:55 Catherine Moorwood, Ph.D. (Barton Lab) - Post-Doctoral Researcher, 
University of Pennsylvania
“Mechanotransduction via the sarcoglycan complex in skeletal muscle”
2:55-3:00 Poster Award
3:00-3:50 Christopher R. Jacobs, Ph.D.
Associate Professor of Biomedical Engineering
Columbia University
"The mechanobiology and biomechanics of primary cilia"
3:50-5:00 Posters & Recption
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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653