Penn Medicine

Actin Cytoskeleton Mechanisms in Health and Disease

Pennsylvania Muscle Institute
Department of Cell and Developmental Biology
Graduate Program in Cell Biology, Physiology, and Metabolism
Perelman School of Medicine at the University of Pennsylvania

December 5, 2014

Organizers: Roberto Dominguez and Michael Way

Register HERE
Program HERE
Lodgings HERE

8:30 – 9:15 Coffee, Poster Setup, and Vendor Show
9:15 – 9:25 E. Michael Ostap, PhD
Director, Pennsylvania Muscle Institute
Perelman School of Medicine
University of Pennsylvania, Perelman School of Medicine
9:25 – 10:05 Bruce L. Goode, PhD
Brandeis University
Mammalian formin regulation and actin-microtubule crosstalk
10:05 – 10:45 Jan Faix, PhD
Hannover Medical School, Hannover, Germany
Coordinating actin-based activities in the front and back of migrating cells
10:45 – 11:00 Coffee Break
11:00 – 11:15 Steven Jones, PhD (Svitkina’s lab)
University of Pennsylvania
Cytoskeletal architecture and assembly of the axon initial segment in hippocampal neurons
11:15 – 12:00 Robert E. Davies Honorary Lecture
Denise Montell, PhD
University of California, Santa Barbara
“Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration”
12:00 – 2:00 Lunch, Poster Session, and Vendor Show
2:00 – 2:40 Janis K. Burkhardt, PhD
Children's Hospital of Philadelphia
Perelman School of Medicine
University of Pennsylvania
F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse
2:40 – 3:15 Giorgio Scita, PhD
University of Milan, School of Medicine, Milano Italy
Endocytic Control of Epithelial Cell Migration
3:15 – 3:30 Katy Ong (DiNardo’s lab)
University of Pennsylvania
Actomyosin network dynamics in epithelial morphogenesis
3:30 – 3:45 Coffee Break
3:45 – 4:00 David Kast, PhD (Dominguez Lab)
University of Pennsylvania, Perelman School of Medicine 
Role of Arp2/3 complex in autophagy
4:00 – 4:40 Michael Way, PhD
London Research Institute. London, UK 
New levels of complexity in Arp2/3 complex function and regulation
4:40 – 5:25 Andrew P. Somlyo Honorary Lecture
Laura M. Machesky, PhD
Beatson Institute for Cancer Research, Glasgow, UK
Role of actin dynamics in invasion and metastasis of cancer
5:30 – 7:00 Cocktails, Poster Session, and Vendor Show
7:00 Speaker Dinner

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Pennsylvania Muscle Institute
Perelman School of Medicine University of Pennsylvania
Director: E. Michael Ostap, Ph.D.

700A Clinical Research Building Philadelphia, PA 19104-6085 Phone: (215) 573-9758 Fax: (215) 898-2653