Penn Neurodegeneration Genomics Center


Leadership

Gerard Schellenberg, PhD

Gerard Schellenberg, PhD
Director, Penn Neurodegeneration Genomics Center
Professor, Pathology & Laboratory Medicine

 gerardsc@pennmedicine.upenn.edu

Faculty Page
Genetics and genomics of Alzheimer’s Disease and related dementia.

 


Li-San Wang, PhD

Li-San Wang, PhD
Co-Director, Penn Neurodegeneration Genomics Center
Associate Professor, Pathology & Laboratory Medicine

 lswang@pennmedicine.upenn.edu

Lab website / Personal website
Genetics of Alzheimer’s Disease and Related Dementia; computational methods for big data in genomics research.
 

 



Affiliated Faculty

Christopher (Casey) Brown, PhD

Christopher (Casey) Brown, PhD
Assistant Professor of Genetics
 chrbro@pennmedicine.upenn.edu

Brown Lab website / Faculty page
Functional human non-coding sequence variation; expression QTL analysis; high throughput approaches for fine-mapping of the causal variants underlying human disease.

 


Alice Chen-Plotkin, MD

Alice Chen-Plotkin, MD
Associate Professor of Neurology
 chenplot@pennmedicine.upenn.edu

Lab website
Unbiased genomic- or proteomic-scale screens; mechanistic followup in relevant systems including neuronal culture and in vivo animal models

 


Shin-Yi Chou, PhD

Shin-Yi Chou, PhD
Arthur F. Searing Professor and Chair, Department of Economics, Lehigh University
 syc2@lehigh.edu

Faculty Page
Health economics and gene-environment interaction analysis of Alzheimer’s disease


Christos Davatzikos, PhD

Christos Davatzikos, PhD
Wallace T. Miller, Sr. Professor of Radiology
 christos@rad.upenn.edu

Faculty page
Biomedical Image Analysis, Machine learning in Imaging, Imaging Biomarkers of Neurologic and Neuropsychiatric Diseases.

 


Struan F.A. Grant, PhD

Struan F.A. Grant, PhD
Associate Professor of Pediatrics
 grants@pennmedicine.upenn.edu

Faculty page
Disease genomics, with a specific focus on pediatrics. High-throughput genotyping and sequencing technologies, combined with statistical and bioinformatic approaches.


F. Brad Johnson, PhD

F. Brad Johnson, PhD
Associate Professor of Pathology and Laboratory Medicine
 johnsonb@pennmedicine.upenn.edu

Faculty page
Molecular biology of aging, cell senescence, Werner syndrome, telomeres, recombination, G-quadruplexes, neurodegeneration, transplantation. 

 


Edward B. Lee, MD, PhD

Edward B. Lee, MD, PhD
Assistant Professor of Pathology and Laboratory Medicine
 Edward.Lee@uphs.upenn.edu

More Information
Molecular pathways associated with neuropathologic inclusions in amyotrophic lateral sclerosis and frontotemporal lobar dementia.

 


Virginia M.-Yee Lee, PhD

Virginia M.-Yee Lee, PhD
John H. Ware 3rd Endowed Professor in Alzheimer's Research
 vmylee@upenn.edu

Faculty page
Biology of tau, synucleins, TDP-43 and amyloid beta precursor proteins (APPs) in health and disease.

 


Fanny Leung, PhD

Fanny Leung, PhD
Research Assistant Professor
 yyee@pennmedicine.upenn.edu

Faculty page

small RNA and proteomic biomarkers for Alzheimer's disease and related dementias, genomic annotation and sequencing pipelines for Alzheimer's disease, RNA-seq bioinformatics


Mingyao Li, PhD

Mingyao Li, PhD
Professor of Biostatistics
 mingyao@pennmedicine.upenn.edu

Faculty page
Statistical genetics, bioinformatics and computational biology for high-throughput genetics/genomics data; single-cell sequencing analysis.

 


Corey T. McMillan, PhD

Corey T. McMillan, PhD
Research Assistant Professor, Neurology
 mcmillac@pennmedicine.upenn.edu

Faculty Page
Neurodegeneration, Neuroimaging, Biomarkers, Frontotemporal Degeneration (FTD), Parkinson's disease (PD), Alzheimer's disease (AD), Amyotrophic Lateral Sclerosis (ALS)

 


Adam Naj, PhD

Adam Naj, PhD
Assistant Professor of Epidemiology in Biostatistics and Epidemiology
 adamnaj@pennmedicine.upenn.edu

More information
Genetic epidemiology for Alzheimer’s disease (AD) and other neurodegenerative diseases.

 


Jennifer E. Phillips-Cremins, PhD

Jennifer E. Phillips-Cremins, PhD
Assistant Professor, Bioengineering (BE)
 jcremins@seas.upenn.edu

Lab website

3D genome folding; Neurodevelopment; Neurodegenerative disease; Trinucleotide repeat expansion disorders; Epigenetics; Genomics


Christian J. Stoeckert Jr., PhD

Christian J. Stoeckert Jr., PhD
Research Professor, Genetics
 stoeckrt@pennmedicine.upenn.edu

Computational Biology and Informatics Laboratory website /
Faculty page
Computational biology and bioinformatics; genomics databases; ontology.

 


John Q. Trojanowski, MD, PhD

John Q. Trojanowski, MD, PhD
William Maul Measy - Truman G. Schnabel, Jr., M.D. Professor of Geriatric Medicine and Gerontology
 trojanow@upenn.edu

Faculty page
Neurodegenerative diseases caused by filamentous aggregates of A-beta, tau and alpha-synuclein; Morphological, genetic, molecular biological and biochemical methods to study neurodegeneration.

 


Vivianna M. Van Deerlin, MD, PhD

Vivianna M. Van Deerlin, MD, PhD
Professor, Pathology and Laboratory
 vivianna@pennmedicine.upenn.edu

Faculty Page

Genetics of neurodegenerative diseases, in particular frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD).


Benjamin F. Voight, PhD

Benjamin F. Voight, PhD
Associate Professor of Pharmacology and Genetics
 bvoight@pennmedicine.med.upenn.edu

Lab website / Faculty page
Statistical genetics, computational biology, and population genetics-based approaches to understand the biological underpinnings and evolutionary history of human phenotypes.

 


Nancy Zhang, PhD

Nancy Zhang, PhD
Associate Professor of Statistics
 nzh@wharton.upenn.edu

Faculty page
Change-point methods, empirical bayes estimation, genomics., model and variable selection, scan statistics, statistical modeling.

 



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