Perelman School of Medicine at the University of Pennsylvania

Penn Center for Pulmonary Biology

  • Lung Imaging courtesy of Edward Morrisey lab.


  • Rho GTPase in GFP-TSC-2 expressing cells. Courtesy of Vera Krymskaya lab.


  • Loss of Lung Lymphatics in CCBE1 Knockout mice. Image Courtesy of Mark Kahn Laboratory.

Penn Center for Pulmonary Biology

Mission Statement

The Penn Center for Pulmonary Biology (PCPB) is an interdisciplinary center focused on the identification and harnessing of disease causing mechanisms that affect the respiratory system. Respiratory disease is the third leading cause of death in the United States, after cardiovascular disease and cancer. While deaths rates due to cardiovascular disease and cancer have been declining, the rates of death due to lung disease has been climbing. In the pediatric population, pulmonary disease remains a leading cause of neonatal distress and death. The PCPB brings together a diverse group of investigators and clinicians to unravel the underlying mechanisms of respiratory disease and begin to utilize such findings to improve clinical medicine.

The Primary Goals of the PCPB are:

  • Create resources at Penn and CHOP to facilitate basic discovery through translational research in pulmonary biology with a focus on using humans as a "model system"
  • Bring together researchers directly involved in pulmonary research as well as those outside the field to build an interactive and rigorous community capable of addressing the most compelling and important questions in pulmonary biology
  • Educate and train the next generation of scientists and physician-scientists who are critical for the future success of pulmonary research.
rotating lung

OPT Image of the Mouse Normal Lung, courtesy of the Morrisey Lab.