Meet a PennMedicine Researcher
J. Kevin Foskett, PhD
J. Kevin Foskett, PhD, Isaac Ott Professor and Chair of Physiology, is the winner of this year’s Stanley N. Cohen Biomedical Research Award, which recognizes a member of the Perelman School of Medicine faculty for a body of work with an emphasis on biomedical research. His pioneering studies of the molecular mechanisms of calcium signaling have resulted in groundbreaking contributions to the understanding of cellular bioenergetics, programmed cell death and Alzheimer’s disease.
Another main focus has been the biophysics, cell biology and physiology of the normal and disease-causing cystic fibrosis transmembrane conductance regulator (CFTR) and its roles in regulating lung salt and water homeostasis. A third focus has been his identification and characterization of a new family of ion channels, and the demonstration that one member plays an essential role in taste perception. His work has addressed challenges of great importance, as evidenced in his publication record over the past five years of more than 30 peer-reviewed and 9 invited review articles, including three in Cell, three in Nature and Nature Cell Biology and others, including the Journal of Clinical Investigation, Neuron, PNAS and Science Signaling, and the more than 3,700 citations of his work. Dr. Foskett’s originality, innovativeness and curiosity have resulted in multiple seminal contributions to a variety of areas of biomedical research.