Meet a PennMedicine Researcher
Michael P. Cancro, Ph.D.
Michael P. Cancro, Ph.D., Professor of Pathology and Laboratory Medicine, has made seminal contributions to our understanding of autoimmunity. His pivotal discovery of the peripheral B cell developmental intermediate now known as the “transitional” B cell permanently changed the accepted paradigm. His work on the mechanisms responsible for B cell survival, homeostasis, and selection has made him a thought leader in the field, and colleagues say that “his body of work … had fundamentally altered thinking about the sites and mechanisms underlying B cell tolerance”. Of most significance, however, is the outcome of his groundbreaking research: Dr. Cancro’s findings led to the first new therapeutic drug for the treatment of systemic lupus erythematosus in the past 50 years. He has made fundamental contributions to autoimmunity.