For more news highlights about basic science research at PennMedicine, see the PennMedicine Benchmarks e-newsletter.
- Personalized Medicine Meets Thyroid Cancer: Drug Targeting BRAF Mutation Helps Patients
25 Jul 2016
In the era of precision medicine, targeting the mutations driving cancer growth, rather than the tumor site itself, continues to be a successful approach for some patients. In the latest example, researchers from Penn Medicine and other institutions found that treating metastatic thyroid cancer patients harboring a BRAF mutation with the targeted therapy vemurafenib —originally approved for melanoma patients with the mutation—showed promising anti-tumor activity in a third of patients.
- Regina Cunningham Appointed Senior Vice President and Chief Nursing Executive for University of Pennsylvania Health System
20 Jul 2016
Regina Cunningham, PhD, RN, FAAN, AOCN, has been named Senior Vice President and Chief Nursing Executive for the University of Pennsylvania Health System, beginning July 1.
- Penn Medicine Researchers to Co-lead $23 Million HIV Cure Grant from NIH
20 Jul 2016
HIV researchers at the Perelman School of Medicine at the University of Pennsylvania and The Wistar Institute will co-lead a five-year, $23 million grant from the National Institutes of Health, as part of the second iteration of the Martin Delaney Collaboratory: Towards an HIV-1 Cure program, that aims to advance basic medical science toward a cure for the disease.
- Want to Cut Calories? New Studies Suggest Placing Orders Before It's Time to Eat
19 Jul 2016
Want to cut calories and make healthier meal choices? Try avoiding unhealthy impulse purchases by ordering meals at least an hour before eating.
- Penn Study Shows Elevated Brain Blood Flow Linked to Anxiety and Mood Symptoms in Females
19 Jul 2016
Prior work by a team of Penn Medicine researchers found that sex-specific changes in cerebral blood flow (CBF) begin at puberty. The team's newest research shows that higher blood flow in emotional brain regions such as the amygdala is associated with higher levels of anxiety and mood symptoms in females.
- New Penn Neurodegeneration Genomics Center Forms National Hub for Alzheimers' Disease Research
18 Jul 2016
Penn Medicine has established the Penn Neurodegeneration Genomics Center (PNGC) as a national focal point for Alzheimer’s disease (AD) genetics research.
- Penn Study: Friendly Competition and a Financial Incentive Increases Team Exercise
15 Jul 2016
Would having your exercise performance compared to that of your peers motivate you do more? A new study suggests it might.
- Hybrid Immune Cells in Early-Stage Lung Cancer Spur Anti-Tumor T Cells to Action
14 Jul 2016
Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a unique subset of tumor associated neutrophils that exhibit hybrid characteristics of two immune cell types -- neutrophils and antigen-presenting cells -- in samples from early-stage human lung cancers.
- Penn Preclinical Study Outlines Cardiovascular Side Effects of Breast Cancer Drug
13 Jul 2016
A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.
- Penn Medicine Announces $3 Million Gift to Establish Unique Pulmonary Program for Patients with Amyotrophic Lateral Sclerosis (ALS) and other Neurodegenerative Diseases
12 Jul 2016
A $3 million gift from University of Pennsylvania alumnus Jay Fishman, and his wife, Randy, will support comprehensive at-home respiratory care for adult Penn Medicine patients with chronic respiratory insufficiency due to neurological, muscular, skeletal or chronic respiratory diseases, including amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord.
- Penn Medicine Information Services Named "Most Wired" by Health and Hospital Networks
11 Jul 2016
Penn Medicine’s Information Services team has been recognized by Health and Hospital Networks with the Most Wired Award for the eighth time in the last decade.
- Insurance Mandates Lead to More Children Diagnosed and Treated for Autism Spectrum Disorder, Penn Study Finds
11 Jul 2016
State mandates requiring commercial health plans to cover the cost of services for children with autism spectrum disorder (ASD) have resulted in an increased number of children being diagnosed and treated for ASD, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
- Neuroscience Researchers Caution Public About Hidden Risks of Self-Administered Brain Stimulation
7 Jul 2016
The growing trend of "do-it-yourself" transcranial direct current stimulation (tDCS) poses hidden risks to healthy members of the public who seek to use the technique for cognitive enhancement. Researchers from the Perelman School of Medicine at the University of Pennsylvania and Beth Israel Deaconess Medical Center, a Harvard Medical School teaching hospital, along with several members of the (cognitive) neuroscience research community warn about such risks involved in home use of tDCS, the application of electrical current to the brain.
- New Therapy Treats Autoimmune Disease Without Harming Normal Immunity
30 Jun 2016
In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.
- Penn Medicine to Develop the Next Generation of Viral Vectors -- called AAV 3.0™ -- for Gene Therapies and Genome Editing
29 Jun 2016
The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0™, to create new viral vectors to find quicker and better treatments for an array of diseases.
- Novel Lipid Lowering Medication Improves Blood Sugar Control in Type 2 Diabetes
28 Jun 2016
High triglycerides – a type of fat, or lipid, in the blood – increase the risk of heart disease and perhaps type 2 diabetes. For the first time, it has been shown that profoundly lowering triglycerides in diabetics improves their insulin sensitivity over time, which helps them maintain healthy glucose – blood sugar – levels.
- Penn Orphan Disease Center Names Director of Neurogenetics and Grant Program Awardees for Rare Genetic Disorder
28 Jun 2016
Ashley R. Winslow, PhD, has been named director of Neurogenetics for the Orphan Disease Center (ODC) in the Perelman School of Medicine at the University of Pennsylvania.
- Penn-CHOP Named CDC Prevention Epicenter Site
27 Jun 2016
The Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia have been awarded over $5 million to serve as a U.S. Centers for Disease Control and Prevention (CDC) Prevention Epicenter site to help develop and test innovative approaches to preventing superbugs and improving patient safety.
- State Medical Home Initiative Slashes Healthcare Costs for Complex Medicaid Patients
27 Jun 2016
Providing Medicaid patients with a primary care “medical home” cut costs of their care by as much as $4,100 a year and lowered their number of doctors visits and hospitalizations, according to a Perelman School of Medicine-led study published today in the Journal of General Internal Medicine.
- Invitation to Cover: Penn Medicine Heart and Vascular VAD Program Celebrates Dedicated Patient Caregivers
22 Jun 2016
The Ventricular Assist Device (VAD) Program at Penn Medicine is hosting a night of dinner, dancing and discussion to celebrate and give thanks to those caregivers who provide support for our VAD patients day in and day out.
- Penn Medicine's Raymond R. Townsend, MD, Director of the Hypertension Program, Receives Physician of the Year Award from the American Heart Association
22 Jun 2016
Raymond R. Townsend, MD, director of the Hypertension Program and a professor of Medicine in Perelman School of Medicine at the University of Pennsylvania, has been named the 2016 Physician of the Year Award of the American Heart Association (AHA).
- Penn Medicine Team and Collaborators Receive NIH Award to Launch Genomics Center on Alzheimer's disease
22 Jun 2016
A five-year, projected $10.8 million award from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), will establish the Coordinating Center for Genetics and Genomics of Alzheimer’s Disease, a joint venture of researchers from the Perelman School of Medicine at the University of Pennsylvania and five other institutions.
- Four NCI Cancer Centers Announce Landmark Research Consortium and Collaborations with Celgene
22 Jun 2016
Today, The Abramson Cancer Center at the University of Pennsylvania, The Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, and The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai announced the establishment of a research consortium focused on accelerating the discovery and development of novel cancer therapeutics and diagnostics for the benefit of patients.
- Penn Medicine Scientist Receives $7.5 Million NIH Renewal Grant for Dementia Research
20 Jun 2016
The National Institute on Aging of the National Institutes of Health has awarded Virginia M.-Y. Lee, PhD, the John H. Ware 3rd Endowed Professor in Alzheimer's Research in the Perelman School of Medicine at the University of Pennsylvania, a $7.5 million, five-year renewal grant to continue pioneering research on a debilitating neurodegenerative disorder.