For more news highlights about basic science research at PennMedicine, see the PennMedicine Benchmarks e-newsletter.
- Penn Medicine and LouLou Foundation Create Program of Excellence for Rare Genetic Disorder that Affects Children
5 Feb 2016
The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.
- Penn Study Identifies Enzyme Key to Link Between Age-Related Inflammation and Cancer
2 Feb 2016
For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
- "Gene Fusion" Mutation Uses Three-Way Mechanism To Drive Childhood Brain Cancers
2 Feb 2016
A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP).
- Viral Gene Editing System Corrects Genetic Liver Disease in Newborn Mice
1 Feb 2016
For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.
- Transplant Centers Often Reject Potential Donor Livers for Sickest Patients in Need, says New Penn Medicine Research
27 Jan 2016
As patients in desperate need of a liver transplant lay waiting, many livers that might give them a new life go unused by centers across the nation, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
- Joseph E. Bavaria Named President of the Society of Thoracic Surgeons
27 Jan 2016
Joseph E. Bavaria, MD, the Brooke Roberts – William Maul Measey Professor in Surgery and director of the Thoracic Aortic Surgery Program in the Perelman School of Medicine at the University of Pennsylvania, has been elected 2016 President of The Society of Thoracic Surgeons (STS).
- Powerful Machine-Learning Technique Uncovers Unknown Features of Important Bacterial Pathogen, According to Penn Study
20 Jan 2016
A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.
- Penn-Engineered Neural Networks Show Hope for Axonal Repair in the Brain, with Minimal Disruption to Brain Tissue
19 Jan 2016
Lab-grown neural networks have the ability to replace lost axonal tracks in the brains of patients with severe head injuries, strokes or neurodegenerative diseases and can be safely delivered with minimal disruption to brain tissue, according to new research from Penn Medicine’s department of Neurosurgical Research.
- Cost of End-of-Life Care in the U.S. is Comparable to Europe and Canada, Finds New Penn Study
19 Jan 2016
Despite widespread perception, the United States does not provide the worst end-of-life care in the world.
- Finding the Needle in a Microbial Haystack: Penn Researchers Test New Pathogen Detection Technology
15 Jan 2016
In a recently published study in Cancer Biology and Therapy, a group of Penn colleagues used a version of the PathoChip microarray, which contains 60,000 probes for all known viruses, as well as a broad range of bacteria, protozoa, fungi, and helminthes, a parasitic worm, to identify the pathogenic agent in the sample of a patient.
- Penn Study Suggests New Recommendations to Reduce Radiation Risk from Digital Screening Mammography
15 Jan 2016
Radiation-induced breast cancer risk from digital mammography is low for the majority of women, but risk is higher in women with large breasts, who received 2.3 times more radiation and required more views per examination to image as much of the breast as possible compared to those with small or average-sized breasts.
- Health Warning Labels May Deter Parents from Purchasing Sugar-Sweetened Beverages for Kids, Penn Study Shows
14 Jan 2016
Health warning labels similar to those found on tobacco products may have a powerful effect on whether parents purchase sugar-sweetened beverages (SSB) for their children, according to a new study led by the Perelman School of Medicine at the University of Pennsylvania.
- Dreamit Partners with Independence Blue Cross and Penn Medicine to Launch Revamped Dreamit Health Program
12 Jan 2016
Leading global start up accelerator Dreamit today announced that it has renewed its partnerships with industry leaders Independence Blue Cross (Independence) and Penn Medicine to advance entrepreneurship and innovation in health care.
- New Understanding of Knee Fibrocartilage Structure Could Aid in Development of Better Replacements and Injury Treatments
8 Jan 2016
Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.
- T Cells That Recognize HER2 Receptor May Be Key to Preventing HER2+ Breast Cancer Recurrence, Penn Study Finds
30 Dec 2015
Recurrence of HER2-positive breast cancer after treatment may be due to a specific and possibly cancer-induced weakness in the patient’s immune system – a weakness that in principle could be corrected with a HER2-targeted vaccine – according to a new study from the Perelman School of Medicine at the University of Pennsylvania.
- New Breast Cancer Drug May be Effective against Other Types of Cancer, Abramson Cancer Center Experts Find
30 Dec 2015
Palbociclib, a new oral drug whose efficacy in combating breast cancer has been demonstrated alone and in combination with endocrine therapy, also has potential to combat other types of cancer, according to a literature review and additional original research conducted by experts at the Abramson Cancer Center (ACC) in the University of Pennsylvania published this month in JAMA Oncology.
- Two Penn Physicians Recognized by Crohn's and Colitis Foundation of America
30 Dec 2015
Penn Medicine’s Gary Lichtenstein, MD, a professor of Medicine and Gary Wu, MD, the Ferdinand G. Weisbrod Professor in Gastroenterology were recently recognized by The Crohn’s and Colitis Foundation of America (CCFA) with 2015 Inflammatory Bowel Disease (IBD) Scientific Achievement Awards.
- Penn Medicine's Anil K. Rustgi, MD, Chief of Gastroenterology, Receives Prestigious Research Professor Award from the American Cancer Society
28 Dec 2015
Anil K. Rustgi, MD, chief of Gastroenterology in the Perelman School of Medicine at the University of Pennsylvania, is once again the recipient of a prestigious Research Professor Award from the American Cancer Society (ACS).
- Penn Medicine Hospitals Receive Baby-Friendly Designation
22 Dec 2015
Penn Medicine’s Pennsylvania Hospital (PAH) and the Hospital of the University of Pennsylvania (HUP) have received designation as a Baby-Friendly Hospital by Baby-Friendly USA, the U.S. authority for the implementation of the Baby-Friendly Hospital Initiative, a global program founded by the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF).
- Risk-Treatment Paradox: Penn Researchers Find Heart Attack Patients Not Always Receiving Lowest-Risk Care
21 Dec 2015
In a comparison of bleeding complications and mortality between two approaches, researchers from the Perelman School of Medicine at the University of Pennsylvania found that those at risk for more bleeding were often treated with a riskier procedure – the transfemoral approach – a demonstration of the so-called risk-treatment paradox.
- Pennsylvania Hospital Receives Prestigious Magnet Recognition for Excellence in Patient Care
21 Dec 2015
Pennsylvania Hospital (PAH) has achieved Magnet status – the highest institutional honor awarded for nursing excellence – from the American Nurses Credentialing Center's (ANCC) Magnet Recognition Program.
- "Quirky" Penn Study Shows Women Less Likely to Hold Academic Medical Leadership Roles than Men with Mustaches
17 Dec 2015
Thirteen percent of department leader positions at top academic medical institutions in the United States are held by women, while nearly 20 percent are held by men with mustaches.
- Weight Loss through Diet Changes Can Improve Sleep at any Body Weight, Says Penn Study
16 Dec 2015
Weight loss due to dietary changes can improve sleepiness at any weight, says a study published by researchers from the Perelman School of Medicine at the University of Pennsylvania this month in the journal Sleep.
- Penn Medicine Information Services Vice President, CIO Named Premier IT Leader by Computerworld
15 Dec 2015
Michael Restuccia, vice president and chief information officer for Penn Medicine, was named one of Computerworld’s Premier 100 Technology Leaders for 2016.