For more news highlights about basic science research at PennMedicine, see the PennMedicine Benchmarks e-newsletter.
- Sleepy Fruitflies Get Mellow: Sleep Deprivation Reduces Aggression, Mating Behavior in Flies, Penn Study Finds
28 Jul 2015
A team of researchers from the Perelman School of Medicine at the University of Pennsylvania used fruitflies to probe deeper into the cellular and molecular mechanisms that govern aggression and sleep.
- Lancaster General Health to Join University of Pennsylvania Health System Aug. 1
28 Jul 2015
Effective Aug. 1, Lancaster General Health (LG Health) will become a member of the University of Pennsylvania Health System (Penn Medicine).
- James Metz Named Chair of Penn Medicine Department of Radiation Oncology
28 Jul 2015
James Metz, MD, has been named the chair of the department of Radiation Oncology in the Perelman School of Medicine at the University of Pennsylvania.
- Penn Scientists Find That Flow Means "Go" for Proper Lymph System Development
27 Jul 2015
The lymphatic system provides a slow flow of fluid from our organs and tissues into the bloodstream. It returns fluid and proteins that leak from blood vessels, provides passage for immune and inflammatory cells from the tissues to the blood, and hosts key niches for immune cells. How this system develops hasn't been well understood, but now researchers from the Perelman School of Medicine at the University of Pennsylvania have found from experiments in mice that the early flow of lymph fluid is a critical factor in the development of mature lymphatic vessels.
- Penn Study Finds Link between Physician Training and Brand Name Prescribing
23 Jul 2015
Physicians in training are twice as likely to order a costly brand-name statin (used to lower blood cholesterol levels) when supervised by senior physicians who prefer those medications in their own practice, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and published online in the Journal of General Internal Medicine.
- Penn Authors Urge Transplantation of Hepatitis C-Infected Kidneys in Some Non-Infected Patients
22 Jul 2015
A new perspective paper written by researchers at the Perelman School of Medicine at the University of Pennsylvania and published in The New England Journal of Medicine suggests that “new antiviral therapies with cure rates exceeding 95 percent should prompt transplant-community leaders to view HCV (hepatitis C virus)-positive organs as a valuable opportunity for transplant candidates with or without pre-existing HCV infection.”
- Penn Medicine Hospitals Named Among Top Ten in the Nation and #1 in Pennsylvania By U.S. News & World Report
21 Jul 2015
Penn Medicine hospitals have been ranked among the top 10 hospitals in the nation, #1 in Pennsylvania, and once again #1 in the Philadelphia metro area by U.S. News & World Report.
- Penn Medicine's John Q. Trojanowski, MD, PhD, Receives Top Honor for Neuropathology Achievement
21 Jul 2015
John Q. Trojanowski, MD, PhD, professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania and director of Penn’s Institute on Aging, has been honored with the American Association of Neuropathologists’ (AANP) Award for Meritorious Contributions to Neuropathology.
- Investigational T-cell Receptor Therapy Achieves Encouraging Clinical Responses in Multiple Myeloma Patients, Penn-led Study Finds
20 Jul 2015
Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person’s own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).
- Penn Medicine Researchers Receive $2 Million Grant from the American Heart Association
17 Jul 2015
Daniel J. Rader, MD, chair of the Department of Genetics at the Perelman School of Medicine at the University of Pennsylvania, and Danish Saleheen, MD, PhD, an assistant professor of Biostatistics and Epidemiology, have been awarded a four-year, $2 million 2015 Grand Challenge Award from the American Heart Association (AHA).
- Increased Radiation Dose Offers No Survival Benefit for Patients with Low-Risk Prostate Cancer, Penn Study Finds
16 Jul 2015
Increased radiation dose is associated with higher survival rates in men with medium- and high-risk prostate cancer, but not men with low-risk prostate cancer, according to a new study from Penn Medicine published this week in JAMA Oncology.
- Hydraulic Fracturing Linked to Increases in Hospitalization Rates in the Marcellus Shale Region, According to Penn Study
15 Jul 2015
Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research from the University of Pennsylvania and Columbia University published this week in PLOS ONE.
- Vision-Restoring Gene Therapy Also Strengthens Visual Processing Pathways in Brain, According to Penn Study
15 Jul 2015
Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia (CHOP), have found evidence that this sight restoration leads to strengthening of visual pathways in the brain, published this week in Science Translational Medicine.
- Penn Investigator Named a 2015 Rita Allen Foundation Scholar
15 Jul 2015
Jeremy E. Wilusz, PhD, an assistant professor of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania, has been awarded a grant from the Rita Allen Foundation
- Penn Medicine Information Services Wins Two Prestigious IS Industry Awards
9 Jul 2015
Penn Medicine’s Information Services team has been recognized by Health and Hospital Networks with two awards, Most Wired and the 2015 Innovator Award.
- Penn's Basser Center for BRCA Names Molecular Scientist David Livingston Winner of 2015 Annual Basser Global Prize
9 Jul 2015
The Basser Center for BRCA at Penn’s Abramson Cancer Center has announced the recipient of its third annual Basser Global Prize. The honor will go to molecular cancer expert David Livingston, MD, Emil Frei Professor of Genetics and Medicine at Harvard Medical School, and deputy director of the Dana-Farber/Harvard Cancer Center.
- Remediating Abandoned, Inner City Buildings Reduces Crime and Violence in Surrounding Areas, Penn Study Finds
8 Jul 2015
Fixing up abandoned buildings in the inner city doesn’t just eliminate eyesores, it can also significantly reduce crime and violence, including gun assaults, researchers from the University of Pennsylvania and Penn’s Perelman School of Medicine report in the first study to demonstrate the direct impact of building remediation efforts on crime.
- Penn Medicine Begins Development of New Cherry Hill Practice
8 Jul 2015
Penn Medicine is planning a new, two-story, 150,000 square foot outpatient medical practice on Route 70 East in Cherry Hill, NJ, scheduled to open in Summer 2016.
- Affordable Care Act Results in Dramatic Drop in Out-of-Pocket Prices for Prescription Contraceptives, Penn Medicine Study Finds
7 Jul 2015
Average out-of-pocket spending for oral contraceptive pills and the intrauterine device (IUD), the two most common forms of contraception for women, has decreased significantly since the Affordable Care Act (ACA) took effect.
- Serious Adverse Events Rare in Healthy Volunteers Participating in Phase I Drug Trials, Penn Medicine Study Finds
7 Jul 2015
Less than 1 percent of 11,000 healthy volunteers who participated in 394 phase I trials for new drugs experienced serious complications, according to a new meta-analysis of participants in non-cancer, phase I medication trials.
- Penn Researchers' New Tracking Method Yields Insights into Mitochondrial Dynamics
1 Jul 2015
Mitochondria, the tiny oxygen reactors that power our cells, can be the keys to health or disease. But while the recognition of their importance has soared in recent years, methods for studying them haven’t always kept pace. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania have devised a powerful new technique that enables the tracking of every mitochondrion as it moves within a cell.
- Jonathan Epstein, MD, Named Chief Scientific Officer for Penn Medicine
29 Jun 2015
Jonathan Epstein, MD, a highly regarded physician-scientist whose work has played a major role in the understanding and treatment of congenital heart disease, has been named executive vice dean and chief scientific officer for Penn Medicine.
- Penn Researchers Identify Stem-like Progenitor Cell that Exclusively Forms Heart Muscle
25 Jun 2015
Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Scientists from the Perelman School of Medicine at the University of Pennsylvania have just taken an important step towards that future by identifying a stem-like “progenitor” cell that produces only heart muscle cells.
- Penn Medicine's Kevin Volpp, MD, PhD, Receives National Institutes of Health 2015 Matilda White Riley Award
23 Jun 2015
Kevin Volpp, MD, PhD, a professor of Medicine and Health Care Management in the Perelman School of Medicine and The Wharton School at the University of Pennsylvania, is receiving the 2015 Matilda White Riley Award, issued today by the National Institutes of Health Office of Behavioral and Social Sciences Research (OBSSR) as part of their 20th Anniversary celebration.