Additional Publications (Pubmed)
Kajimura, S., Seale, P., Kubota, K., Lunsford, E., Frangioni, J.V., Gygi, S.P., Spiegelman, B.M. (2009). Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature 460, 1154-58
Seale, P., Lazar, M.A. (2009). Brown fat in humans: turning up the heat on obesity. Diabetes 58, 1482-4. Preview.
Seale, P., Kajimura, S., Spiegelman, B.M. (2009). Transcriptional control of brown adipocyte development and physiological function--of mice and men. Genes Dev. 23, 788-97. Review.
Seale, P., Bjork, B., Yang, W., Kajimura, S., Kuang, S., Scime, A., Devarakonda, S., Chin, S., Conroe, H.M., Erdjument-Bromage, H., Tempst, P., Rudnicki, M.A., Beier, D.R., Spiegelman, B.M. (2008). PRDM16 Controls a Brown Fat/Skeletal Muscle Switch. Nature, 454, 961-967.
Kajimura S., Seale P., Tomaru T, Erdjument-Bromage H, Cooper M.P., Ruas J.L., Chin S., Tempst P., Lazar M.A, Spiegelman B.M. (2008). Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev. 22, 1397-409.
Holterman, C.E., LeGrand, F., Kuang, S., Seale, P., Rudnicki, M.A. (2007). Megf10 regulates the satellite cell myogenic program. J. Cell Biol. 179, 911-922.
Seale P., Kajimura S., Yang W., Chin S., Rohas L.M., Uldry M., Tavernier G., Langin D., Spiegelman B.M. (2007). Transcriptional control of brown fat determination by PRDM16. Cell Metab. 6, 38-54.
Handschin C., Kobayashi Y.M., Chin S., Seale P., Campbell K.P, Spiegelman B.M. (2007). PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes Dev. 21, 770-783.
Uldry, M., Yang, W., St-Pierre, J., Lin, J., Seale, P., Spiegelman, B.M. (2006). Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 3, 333-341.
Kuang, S., Chargé, S.B., Seale, P., Huh, M., Rudnicki, M.A. (2006). Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis. J Cell Biol. 172, 103-113.