Mariana Torrente is a post-doctoral researcher. She received dual bachelor’s degrees in Chemistry and Biochemistry from the Florida Institute of Technology in 2005 and her Ph.D. in Chemistry in 2010 from Princeton University where she comprehensively cataloged chromatin proteins -particularly histones- during biologically significant processes using high-end mass spectrometry proteomics. Prior to joining us as a PENN-PORT fellow, she was a NIH NRSA fellow at the Penn State University College of Medicine.

Publications

Torrente, M.P, Freeman, W.M., and Vrana, K.V. Proteomic Biomarkers of Alcohol Abuse. Expert Reviews in Proteomics, 9(4), 425-36 (2012)

Torrente, M.P., Zee, B.M.; Young, N.L.; Baliban, R.C; Leroy, G.; Floudas, C.A.; Hake, S.B.; Garcia B.A., Proteomic Interrogation of Human Chromatin. PLos One, 6, (9), e24747 (2011)

Plazas-Mayorca, M.D. and Vrana, K.E. Proteomic investigation of epigenetics in neuropsychiatric disorders: A missing link between genetics and behavior? Journal of Proteome Research, 10 (1), 58–65 (2011)

Plazas-Mayorca, M.D., Bloom, J.S., Zeissler, U., LeRoy, G., Young, N.L., DiMaggio, P.A., Krugylak, L., Schneider, R. and  Garcia, B.A. Quantitative Proteomics Reveals Direct and Indirect Alterations in the Histone Code Following Methyltransferase Knockdown. Molecular BioSystems, (6), 1719-1729 (2010)

Baliban, R. C.; DiMaggio, P. A.; Plazas-Mayorca, M.D.; Young, N. L.; Garcia, B. A.; Floudas, C. A.,  A novel approach for untargeted post-translational modification identification using integer linear optimization and tandem mass spectrometry. Molecular &Cellular Proteomics, 9, (5), 764-79 (2010)

Young, N.L.*; Plazas-Mayorca, M.D.*; Flaniken, I.Z.; DiMaggio, P. A.; Beltran, A.; Mishra, N.; LeRoy, G.; Floudas, C. A.; Garcia, B.A., Combined top down and bottom up mass spectrometry analysis of high mobility group protein A1a. Journal of the American Society for Mass Spectrometry, 21, (6), 960-70 (2010). *These authors contributed equally to this work

Young, N.L.; Plazas-Mayorca, M.D.; Garcia, B.A.  Systems-wide proteomic characterization of combinatorial post-translational modification patterns.  Expert Reviews in Proteomics, 7, (1), 79 (2010)

Plazas-Mayorca, M.D.; Zee, B.M.; Young, N.L.; Fingerman, I.M.; LeRoy, G.; Briggs, S.D.; Garcia B.A., One-pot shotgun quantitative mass spectrometry characterization of histones.  Journal of Proteome Research, 8, (11), 5367-74 (2009).

Young, N. L.; DiMaggio, P. A.; Plazas-Mayorca, M. D.; Baliban, R. C.; Floudas, C. A.; Garcia, B. A., High-throughput characterization of combinatorial histone codes. Molecular & Cellular Proteomics, 8, (10), 2266-84 (2009).

Leroy, G.; Weston, J. T.; Zee, B. M.; Young, N. L.; Plazas-Mayorca, M. D.; Garcia, B. A., Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Molecular & Cellular Proteomics, 8, (11), 2432-42 (2009).

Leroy, G.; Plazas-Mayorca, M. D.; Young, N. L.; Garcia, B. A., Decoding the histone code by quantitative proteomics.  Molecular & Cellular Proteomics, 8, (8), Supplement 1, S11, (2009) 

Plazas-Mayorca, M.D., Young, N.L., and Garcia, B.A. Identification of Differentially Expressed Histone Codes Using HILIC and Mass Spectrometry. American Biotechnology Laboratory, 27 (2), 10-2 (2009).

Young, N.L., Plazas-Mayorca, M.D., and Garcia, B.A. A Method to Separate and Characterize Modified Forms of Histones Using HILIC and Electron Transfer Dissociation-Mass Spectrometry. American Biotechnology Laboratory, January 2009, 27 (1), 23-5 (2009).