2014

July 16, 2014:

 

Meredith's paper is accepted at Disease Models & Mechanisms!

July 4, 2014:

 

Meredith's paper featured as Key Scientific Article by Global Medical Discovery.

July 3, 2014:

 

Collaborative work on PML with Lili Guo and Xiaolu Yang at Penn is published in Mol. Cell! See also preview, cover, and Penn News Story.

June 5, 2014:

 

Jim presents seminar at Gordon Conference: Biopolymers-Mechanisms of Biomolecular Interactions: From Physical Principles to Biological Insights.

May 26, 2014:

 

Jim presents plenary lecture at the inaugural “Biophysics of Amyloids and Prions" meeting at Castel dell’ Ovo, Naples, Italy.

May 14, 2014:

 

Lin wins best poster at the Annual Sylvan M. Cohen Retreat of the Institute on Aging!

May 7, 2014:

 

Rachel is accepted into The University Scholars Program.

May 7, 2014:

 

Meredith's methods paper on isolating potentiated Hsp104 variants is accepted at J. Vis. Exp!

May 2, 2014:

 

Elizabeth presents poster at Cold Spring Harbor Laboratory Meeting. Molecular chaperones and stress responses.

May 1, 2014:

 

Meredith presents poster at Cold Spring Harbor Laboratory Meeting. Molecular chaperones and stress responses.

May 1, 2014:

 

Jim presents seminar at Cold Spring Harbor Laboratory Meeting. Molecular chaperones and stress responses.

April 23, 2014:

 

Rachel publishes video: Reengineering Hsp104 to Disaggregate Proteins Involved in Neurodegenerative Disease.

April 11, 2014:

 

Elizabeth defends her Ph.D. thesis!!!!

April 9, 2014:

 

Jim presents seminar at Target ALS Annual Meeting at Columbia University.

April 2, 2014:

 

Meredith selected as a finalist for the 2014 Regeneron Prize for Creative Innovation in a Postdoctoral Fellow.

March 30, 2014:

 

Meredith's perspective article is accepted in Cell Cycle.

March 28, 2014:

 

Laura and Mike present at FRD.

March 26, 2014:

 

Jim presents seminar at the Institute for Diabetes, Obesity and Metabolism at Penn.

March 21, 2014:

 

Jim wins Sarcoma Pilot Grant from the Abrahamson Cancer Center!

March 11, 2014:

 

Aaron Gitler presents collaborative work with Shorter lab at The Packard Center Annual Symposium.

February 25, 2014:

 

The Life Extension Foundation supports our work on Hsp104.

February 24, 2014:

 

Meredith's paper on reprogramming Hsp104 spotlighted in ACS Chem. Biol.

February 21, 2014:

 

Lin & Jim present at Team Gitler Target ALS meeting in Long Beach, CA.

February 17, 2014:

 

Alzforum covers collaborative work on FUS with Eric Huang's group.

February 14, 2014:

 

Collaborative work on FUS with Eric Huang's group at UCSF featured as Scientific Show Stopper in J. Clin. Invest.

February 12, 2014:

 

Jim becomes Associate Editor of Frontiers in Protein Folding, Misfolding and Degradation

February 7, 2014:

 

Mike presents at Genetics Postdoctoral & Graduate Student Research Talks.

January 16, 2014:

 

Meredith's paper on reprogramming Hsp104 is published in Cell! See Penn press release. See UA press release. See WHYY Newsworks segment. See MDA/ALS news story.

 

 

2013

December 17, 2013:

 

Laura presents poster at The American Society for Cell Biology Annual Meeting in New Orleans.

December 16, 2013:

 

Alice presents poster at The American Society for Cell Biology Annual Meeting in New Orleans.

December 14, 2013:

 

Mariana's commentary is accepted in Prion!

December 6, 2013:

 

Penn Medicine highlights our work on RNA-binding proteins with prion-like domains

November 27, 2013:

 

Collaborative work on FUS with Eric Huang's group at UCSF is accepted at J. Clin. Invest.!

November 26, 2013:

 

Morgan's paper is accepted in J. Biol. Chem.!

November 21, 2013:

 

Jim presents seminar at The Stanford Institute for Neuro-Innovation & Translational Neurosciences at Stanford University.

November 20, 2013:

 

Meredith's paper is accepted in Cell!

November 8, 2013:

 

Jim presents seminar at the NINDS sponsored meeting on Mechanisms of Misfolded Protein Propagation in Neurodegenerative Diseases in San Diego.

November 8, 2013:

 

Elizabeth wins the A. Joshua Wand Award for best poster at the Dr. George Raiziss 30th Annual Retreat at Skytop Lodge, Poconos. PA.

November 8, 2013:

 

Morgan delivers P. Leslie Dutton Award seminar at the Dr. George W. Raiziss 30th Annual Retreat at Skytop Lodge, Poconos. PA.

November 7, 2013:

 

Meredith presents seminar at the Dr. George W. Raiziss 30th Annual Retreat at Skytop Lodge, Poconos. PA.

October 24, 2013:

 

Laura presents seminar at the PGG symposium at the National Constitution Center and wins the John S. O'Brien Award for best oral presentation!

September 27, 2013:

 

Jim presents seminar at the Packard Center PI Meeting at Johns Hopkins Medicine Brain Science Institute

September 17, 2013:

 

The Packard Center for ALS Research at Johns Hopkins funds our collaborative efforts with Aaron Gitler's group.

September 9, 2013:

 

Jim presents seminar at the Dept. of Biochemistry and Molecular Biology at Penn State Hershey Medical Center.

August 8, 2013:

 

Jim presents seminar at The Ellison Medical Foundation Colloquium on the Biology of Aging at Marine Biological Laboratory, Woods Hole, MA.

August 6, 2013:

 

Morgan wins the 2013 P. Leslie Dutton Award for Outstanding Publication by a BMB student!

July 25, 2013:

 

Jim presents at the Motor Neuron Center at Columbia University.

July 25, 2013:

 

Mimi's paper is accepted in PLoS Genetics!

July 23, 2013:

 

Mimi defends her Ph.D. thesis!!!

July 23, 2013:

 

Laura presents seminar at CBI Retreat at Bryn Mawr College

July 22, 2013:

 

Jim receives a Muscular Dystrophy Association Grant Award! See MDA press release See Penn press release See MDA page

July 19, 2013:

 

Collaborative work on yeast aging with Iva Tolić-Nørrelykke accepted for publication in Current Biology! See Science Daily news story. See Curr Biol Dispatch. See Science Editor's choice.

July 18, 2013:

 

Morgan defends her Ph.D. thesis!!!

July 8, 2013:

 

NIH Common Fund features prion-like domain concept.

July 1, 2013:

 

Jim becomes Associate Professor of Biocehmistry and Biophysics with tenure.

June 20, 2013:

 

Alice selected as a 2013 predoctoral trainee for Dr. Virginia Lee’s T32 Grant: 'Training in Age-Related Neurodegenerative Diseases'

June 18, 2013:

 

Jim presents seminar at the 2013 Israeli-American Kavli Frontiers of Science Symposium at the Arnold and Mabel Beckman Center, Irvine, CA.

June 13, 2013:

 

Jim presents at The Queen's College, University of Oxford.

June 12, 2013:

 

Jim presents seminar at The Sir William Dunn School of Pathology at the University of Oxford.

May 29 2013:

 

Meredith wins one year American Heart Association post-doctoral fellowship!

May 28, 2013:

 

Addendum with J. Paul Taylor accepted for publication in Rare Diseases!

May 21, 2013:

 

Alice passes her prelim!

May 17, 2013:

 

Jim promoted to Associate Professor of Biochemistry and Biophysics, with tenure, effective July 1! Toast

May 14, 2013:

 

'Unraveling mechanisms in RNA-binding protein-mediated ALS' consortium comprising: Aaron Gitler (Stanford), Jim Shorter (Penn), J. Paul Taylor (St. Jude), Clotilde Lagier-Tourenne (UCSD), Steve Finkbeiner (UCSF), and Don Cleveland (UCSD) is funded by Target ALS!

April 29, 2013:

 

Review on stress granules as crucibles of ALS pathogenesis with Rose Li, Oliver King, and Aaron Gitler published at J. Cell Biol.

April 26, 2013:

 

Morgan & Meredith present at FRD.

April 25, 2013:

 

hnRNPA1 & hnRNPA2B1 study featured in Cell.

April 23, 2013:

 

Rebecca wins Fulbright scholarship!

April 17, 2013:

 

Rebecca presents poster at Sigma Xi Research Day at Thomas Jefferson University.

April 11, 2013:

 

Henry wins the 'Founders Award' for best poster at The Annual Biochemistry Major Poster Session!

March 18, 2013:

 

Jim presents seminar at Edward A. Doisy Department of Biochemistry and Molecular Biology at St. Louis University.

March 15, 2013:

 

Mike presents at Genetics Postdoctoral & Graduate Student Research Talks.

March 7, 2013:

 

Alzforum features hnRNPA1 & hnRNPA2B1 study.

March 4, 2013:

 

TheScientist covers hnRNPA1 & hnRNPA2B1 study.

March 3, 2013:

 

The iceberg emerges! Emily, Zamia, and Alice's collaborative work with Paul Taylor's group at St. Jude Children's Research Hospital is published in Nature! See Penn press release. See St. Jude press release. See ALSA press release.

February 28, 2013:

 

Jim presents seminar on collaborative work with Gitler and Taylor labs at The Packard Center Annual Symposium.

February 25, 2013:

 

Jim presents seminar at 65th Birthday Symposium for Graham Warren at The University of Vienna! Homage to Graham.

February 6, 2013:

 

Morgan and Meredith present posters at the 57th Annual Meeting of the Biophysical Society in Philadelpia.

February 3, 2013:

 

Liz presents poster at the 57th Annual Meeting of the Biophysical Society in Philadelpia.

 

 

2012

December 16, 2012:

 

Liz, Mike, Laura, and Meredith present at The American Society for Cell Biology Annual Meeting in San Francisco.

December 10, 2012:

 

R01 proposal funded by the National Institute Of General Medical Sciences!

November 21, 2012:

 

Morgan's paper published in Chemistry & Biology!

November 16, 2012:

 

Aaron Gitler & Jim present at the Packard Center PI Meeting at Johns Hopkins Medicine Brain Science Institute

November 8, 2012:

 

Morgan's paper published in Cell! See Preview by Amber Murray and Jeff Kelly. See also Penn press release.

October 8, 2012:

 

Jim is selected as recipient of the 2012 Michael S. Brown New Investigator Research Award, which recognizes emerging faculty engaged in innovative discoveries.

October 1, 2012:

 

Mariana starts her PENN-PORT post-doctoral fellowship in the lab.

September 11, 2012:

 

Collaborative work with Gitler lab is accepted at Nature Genetics! The study suggests that the lariat-debranching enzyme, Dbr1, is a drug target for FUS and TDP-43 proteinopathies. See also News & Views by Shuying Sin and Don Cleveland. See SGD spotlight, Packard Center Press Release, and NINDS story.

August 21, 2012:

 

Jim presents seminar at University of Texas Southwestern Medical Center!

July 1, 2012:

 

R21 proposal funded by the Eunice Kennedy Shriver National Institute of Child Health & Human Development!

June 14, 2012:

 

Elizabeth presents seminar at the Dr. George W. Raiziss 29th Annual Retreat at Swarthmore College.

June 4, 2012:

 

Jim presents seminar at Gordon Conference: Biopolymers - In Vitro, In Silico, and in the Cell.

May 22, 2012:

 

Laura's review on amyloid and HIV is accepted at Biology!

May 9, 2012:

 

Paper with Martin Duennwald at BBRI on small heat shock proteins as potentiators of amyloid dissolution in yeast and humans is accepted at PLoS Biology! See Penn Medicine press release

May 3, 2012:

 

Jim presents seminar at Cold Spring Harbor Laboratory Meeting. Molecular chaperones and stress responses.

April 19, 2012:

 

Beatrice wins the 'Founders Award' for best poster at The Annual Biochemistry Major Poster Session!

April 13, 2012:

 

Mike presents at Genetics Postdoctoral & Graduate Student Research Talks.

March 22, 2012:

 

Manuscript evaluating role of EWSR1, an RRM-bearing prion candidate, in ALS accepted at Hum. Mol. Genet.

March 8, 2012:

 

Aaron Gitler presents seminar on collaborative work with Shorter lab at The Packard Center Annual Symposium.

February 25, 2012:

 

Brief review on RNA-binding proteins in ALS is accepted at Neurol. Res. Int.

February 1, 2012:

 

Morgan is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

January 19, 2012:

 

Jim presents invited seminar at Penn CNDR

January 6, 2012:

 

Research report with Oliver King and Aaron Gitler entitled: 'The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.' accepted at Brain Research.

 

 

2011

December 28, 2011:

 

Disease Models and Mechanisms highlights TAF15 paper.

December 27, 2011:

 

TAF15 paper featured on the cover of PNAS!

December 7, 2011:

 

The Packard Center for ALS Research at Johns Hopkins renews our funding to collaborate with Aaron Gitler's group to study FUS misfolding

December 6, 2011:

 

Jim presents invited seminar at The American Society for Cell Biology Annual Meeting, Minisymposium, Cellular Mechanism of Disease and Aging. Featured in Mol. Biol. Cell.

December 6, 2011:

 

Nature Reviews Neurology features TAF15 paper.

December 2, 2011:

 

Henry presents seminar at CBI symposium

November 25, 2011:

 

Alzforum features connection between RNA-binding proteins with prion-like domains and neurodegeneration

November 18, 2011:

 

Alzforum features the 'Gitler-Shorter approach' to ALS gene discovery

November 10, 2011:

 

Jim presents invited seminar at the 6th Brain Research Conference, RNA-Binding Proteins in Neurological Disease (official satellite to the 2011 Meeting of the Society for Neuroscience)

November 6-10, 2011:

 

Morgan (poster) and Elizabeth (poster+talk) present at the 9th International Conference on AAA proteins in Kumamoto, Japan.

October 28, 2011:

 

Mimi wins poster prize at the CNDR Retreat!

October 13, 2011:

 

Collaborative work with Aaron Gitler's group on predicting new ALS genes with prion-like domains accepted at PNAS! See highlight in PNAS. See press release from the Packard Center. See Penn press release.

September 23, 2011:

 

Jim's paper on the mammalian disaggregase machinery accepted at PLoS ONE!

August 12, 2011:

 

Jim presents invited seminar at Boston Biomedical Research Institute.

August 10, 2011:

 

Commentary on RNA-binding proteins with prion-like domains in ALS and FTLD-U featured on the cover of Prion. Cover design and scientific illustrations by Lili Guo.

July 29, 2011:

 

Morgan presents seminar at CBI Retreat at Villanova University.

July 19, 2011:

 

Commentary on RNA-binding proteins with prion-like domains in ALS and FTLD-U with Aaron Gitler accepted at Prion.

July 19, 2011:

 

Jim presents invited seminar at Gordon Conference: 'Stress Proteins in Growth, Development and Disease'

July 19, 2011:

 

Morgan's review is accepted at BBA-Molecular Cell Research!

July 1, 2011:

 

MDA (Muscular Dystrophy Association) features our work on FUS

June 24, 2011:

 

Morgan wins a poster prize at The Dr. George Raiziss 28th Annual Retreat!

June 24, 2011:

 

Elizabeth receives an honorable mention for her poster at The Dr. George Raiziss 28th Annual Retreat!

June 19, 2011:

 

Meredith's commentary is accepted at the Journal of Clinical Investigation!

June 15, 2011:

 

Elizabeth's Hsp104 purification protocol is accepted at the Journal of Visualized Experiments!

May 26, 2011:

 

Meredith wins a two year American Heart Association Post-Doctoral Fellowship!

May 20, 2011:

 

Aaron Gitler & Jim present at the Packard Center PI Meeting at Johns Hopkins Medicine Brain Science Institute

May 12, 2011:

 

Laura passes her prelim!

May 10, 2011:

 

Alzforum covers Zamia's paper with Zhihui from the Gitler lab concerning FUS and ALS.

April 29, 2011:

 

Mike passes his prelim!

April 28, 2011:

 

Eunice wins award for her superb poster at The Annual Biochemistry Major Poster Session!

April 28, 2011:

 

Mike selected as a 2011 predoctoral trainee for Dr. Meera Sundaram's T32 Predoctoral Training Grant: Genetics Training Program!

April 26, 2011:

 

Penn Medicine highlights Zamia's paper with Zhihui from the Gitler lab concerning FUS and ALS.

April 5, 2011:

 

Laura wins a National Science Foundation (NSF) Graduate Research Fellowship!

March 31, 2011:

 

Jim presents seminar on collaborative work with Gitler lab at The Packard Center Annual Symposium

March 21, 2011:

 

Jim presents invited seminar at a Keystone Symposia: AAA+ and Related ATP-Driven Protein Machines: Structure, Function and Mechanism

March 1, 2011:

 

Zamia's paper with Zhuhui from the Gitler lab accepted at PLoS Biology! See also back to back paper from Greg Petsko, Dagmar Ringe and colleagues at Brandeis University and PLoS Biology synopsis.

January 28, 2011:

 

Penn Medicine highlights our biochemical studies with purified TDP-43.

 

 

2010

December 4, 2010:

 

Jim presents invited seminar at Cold Spring Harbor Laboratory Meeting. Neurodegenerative Diseases: Biology & Therapeutics.

December 3, 2010:

 

Mimi presents poster at Cold Spring Harbor Laboratory Meeting. Neurodegenerative Diseases: Biology & Therapeutics.

October 8, 2010:

 

The Packard Center for ALS Research at Johns Hopkins funds our collaboration with Aaron Gitler's group to study FUS misfolding.

September 20, 2010:

 

Jim presents invited seminar at Biochemistry & Biology Dept. at Haverford College

September 12, 2010:

 

Review with Martin Duennwald accepted in Prion.

September 9, 2010:

 

Jim presents at The Society for General Microbiology Meeting at The University of Nottingham.

June 22, 2010:

 

Mimi is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

May 28, 2010:

 

Elizabeth and Mimi are awarded American Heart Association Predoctoral Fellowships!

May 18, 2010:

 

Morgan's journal club published in Disease Models & Mechanisms!

May 10, 2010:

 

Jim receives a Grand Challenges Explorations Award from the Bill and Melinda Gates Foundation! Gates Foundation Press Release. Penn Press Release.

April 13, 2010:

 

Morgan passes her prelim!

April 8, 2010:

 

Jim's Molecular Biosystems review accepted.

April 6, 2010:

 

Morgan is accorded an Honorable Mention from the National Science Foundation.

March 25, 2010:

 

Noelle is among the prizes at Penn Vet Phi Zeta Student Research Day!

March 2, 2010:

 

Noelle's abstract selected for an oral presentation at Penn Vet Phi Zeta Student Research Day!

February 16, 2010:

 

Mimi's review with Brian from the Gitler group accepted!

 

 

2009

November 13, 2009:

 

Morgan wins Chemistry-Biology Interface (CBI) Fellowship!

September 29, 2009:

 

R21 proposal to study mechanisms of TDP-43 aggregation and disaggregation funded by the National Institute of Neurological Disorders and Stroke (NINDS)!

September 9, 2009:

 

Jim presents invited seminar at Children's Hospital of Philadelphia (CHOP) Cell Pathology Series.

September 8, 2009:

 

Hsp104 review by Shilpa and Mimi accepted!

September 4, 2009:

 

Blake's paper accepted in Nature Chemical Biology! See Penn press release.

August 13, 2009:

 

Elizabeth selected as a 2009 predoctoral trainee for Dr. Mitch Lewis’ T32 Grant: Structural Biology Training Program

July 31, 2009:

 

Mimi selected as the 2009 predoctoral trainee for Dr. Virginia Lee’s T32 Grant: 'Training in Age-Related Neurodegenerative Diseases'

July 13, 2009:

 

Jim presents at the 8th International Meeting on AAA Proteins. See pictures.

July 1, 2009:

 

Jim receives a New Scholar in Aging Award from the Ellison Medical Foundation.

June 19, 2009:

 

Elizabeth Sweeny wins the A. Joshua Wand Award for best poster at The Dr. George Raiziss 26th Annual Retreat!

June 5, 2009:

 

TDP-43 paper featured by Alzforum

May 22, 2009:

 

TDP-43 collaboration with Gitler group published in The JBC!

May 14, 2009:

 

Jim presents invited seminar at Penn CNDR

May 7, 2009:

 

Mimi passes her prelim!

May 5, 2009:

 

Jim presents invited seminar at The Cell Biology Dept. at The University of Texas Southwestern Medical Center at Dallas.

April 24, 2009:

 

Jim presents invited seminar at Biochemistry Dept. at Haverford College

April 9, 2009:

 

Motor mechanism of Hsp104 function published in Molecular Cell!

April 7, 2009:

 

Elizabeth passes her prelim!

March 30, 2009:

 

David accepted into Penn MD/PhD program!

March 13, 2009:

 

Jim wins Penn Diabetes and Endocrinology Research Center (DERC) Pilot Award!

February 26, 2009:

 

Noelle accepted into Penn VMD/PhD program!

February 5, 2009:

 

Jim presents invited seminar at Penn Chemistry Dept. Biological Chemistry Seminar Series

January 22, 2009:

Elizabeth's first review accepted in Prion!

 

 

2008

October 2, 2008:

Hsp104, Hsp70 and Hsp40 interplay in Sup35 prionogenesis published in The EMBO J!

August 14, 2008:

Hsp104 and Parkinson's Disease work published in The JCI! See the press release.

June 20, 2008:

Elizabeth Sweeny and Kathleen Molnar among the prizes for best poster at The Dr. George Raiziss 25th Annual Retreat!

June 4, 2008:

Blake's first review is published in Nature Structural & Molecular Biology!

June 2, 2008:

Research on small molecule DAPH highlighted in National Institute of Health News Release: "Molecule Dissolves Fibers Found in Alzheimer’s Disease Patients."

May 16, 2008:

Huan's latest work highlighted by Penn Medicine: "Researchers Discover How a Small Molecule Can Take Apart Disease-Associated Protein Fibers."

May 14, 2008:

Huan's first paper is published in PNAS!

February 8, 2008:

Collaborative work on Sse1 with Heather Sadlish accepted at PLoS ONE!

January 25, 2008:

Neurology Journal Devotes Special Issue to Penn Research. See the press release.

 

 

2007

December 28, 2007:

Cryo-EM models of Hsp104 structure published in Cell!

October 1, 2007:

Jim is awarded NIH Director's New Innovator Award! See the press release.

May 31, 2007:

Jim presents invited seminar at Penn CNDR

May 2, 2007:

Jim wins Penn Institute of Aging Pilot Award!

April 27, 2007:

Jim wins Penn Alzheimer's Disease Core Center Pilot Award!

April 1, 2007:

Shorter lab opens!!

 




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University of Pennsylvania