Shorter Lab at Penn:

• Faculty Profile
• Google Scholar
• PubMed
• ResearchGate
• ORCiD

Joining the Lab:

• Employment opportunites in the lab

How to:

• Keep a good lab notebook
• Survive a Ph.D.
• Be a successful post-doc
• Give a good talk
• Give a good chalk talk
• Choose a good scientific problem
• Swim with sharks
• Be a successful scientist

Seminars:

• Kavli Frontiers of Science, June 2013 (Jim Shorter): The Opportunity of Proteostasis
• YouTube, April 2014 (Rachel Weitzman): Reengineering Hsp104 to Disaggregate Proteins Involved in Neurodegenerative Disease
• YouTube, April 2015 (Megan Noll): Characterizing Hyperactive Mutations of Hsp104 in terms of Protein Structure
• Brain Res., May 2016 (Zach March): Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease
• ALSA webinar, July 2016 (Jim Shorter): Disaggregase modalities for ALS
• ADDF, September 2016 (Korrie Mack): Suppressing Abeta toxicity with potentiated Hsp104 variants
• ADDF, September 2016 (JiaBei Lin): Developing therapeutic protein disaggregases for Alzheimer’s Disease
• CReATe Virtual Journal Club, June 2017 (Meredith Jackrel): Protein Remodeling Factors as Potential Therapeutics for Neurodegenerative Disease
• YouTube, April 2018 (Mustafa Salim): Disaggregation of alpha-synuclein amyloid fibrils by Hsp70
• YouTube, April 2018 (Alex Zhou): Utilizing Protein Disaggregase Chaperones to Treat Neurodegenerative Disease: Hsp104
• YouTube, April 2019 (Addie Shelley, Sean Na, and Joseph Chong): Hsp104 Disaggregation of Amyloid Fibrils
• YouTube, April 2019 (Daniel Rodriguez, Baotram Nguyen, and Gracelynn Soesanto): The Implication of Mutated FUS in ALS

Collaborating Labs at Penn:

• Paul Bates (Microbiology)
• Ben Black (Biochemistry & Biophysics)
• Nancy Bonini (Biology)
• Jason Burdick (Bioengineering)
• Walter Englander (Biochemistry & Biophysics)
• Kushol Gupta (Biochemistry & Biophysics)
• Donna Huryn (Chemistry)
• Ophir Shalem (Genetics)
• John Trojanowski & Virginia Lee (Center for Neurodegenerative Disease Research)
• Xiaolu Yang (Cancer Biology)

Collaborating Labs outside Penn:

• Patrick Aebischer (Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne)
• Mike Bassik (Stanford)
• Steve Buchwald (MIT)
• Guy & Kim Caldwell (University of Alabama)
• Yuh Min Chook (UTSW)
• Don Cleveland (UCSD)
• Todd Cohen (UNC Chapel Hill)
• Bill DeGrado (UCSF)
• Chris Donnelly (University of Pittsburgh)
• Dorothee Dormann (Ludwig-Maximilians-University Munich)
• D. Allan Drummond (Chicago)
• Martin Duennwald (University of Western Ontario)
• Steve Finkbeiner (Gladstone/UCSF)
• Aaron Gitler (Stanford University)
• Oliver King (UMass, Worcester)
• Andrzej Joachimiak (Argonne)
• Clotilde Lagier-Tourenne (MGH)
• Aaron Lucius (University of Alabama, Birmingham)
• Stavroula Mili (NIH)
• Jan Münch (University of Ulm)
• Sua Myong (Johns Hopkins University)
• Udai Pandey (University of Pittsburgh)
• Piera Pasinelli (Thomas Jefferson University)
• Len Petrucelli (Mayo Clinic)
• Daniel Southworth (UCSF)
• Shuying Sun (Johns Hopkins University)
• J. Paul Taylor (St. Jude Children's Research Hospital)
• Jernej Ule (The Francis Crick Institute)
• Jiou Wang (Johns Hopkins University)