Pack Lab

Dr. Allan Pack is pursuing research on genetics/genomics of sleep apnea. His laboratory is conducting studies in Drosophila and mice and translating these findings to humans. A particular focus of Dr. Pack’s work is to evaluate whether there are genetic determinants to outcomes of sleep apnea, in particular, sleepiness. Studies are ongoing to evaluate molecular mechanisms of sleepiness and sleep promotion using both hypothesis-driven and discovery science. Techniques being used include behavioral/sleep studies in Drosophila and mice, RT-PCR, Western analysis of protein, expression profiling, laser microcapture dissection, and immunohistochemistry. Dr. Pack is committed to research training and directs two training grants from the National Institutes of Health.

Publications

Mackiewicz M, Zimmerman JE, Shockley KR, Churchill GA, Pack AI. What are microarrays teaching us about sleep? Trends Mol Med. 2009 Feb;15(2):79-87. Epub 2009 Jan 21.

Zimmerman JE, Raizen DM, Maycock MH, Maislin G, Pack AI. A video method to study Drosophila sleep. Sleep. 2008 Nov 1;31(11):1587-98.

Rotation Projects

Education
University of Glasgow, Scotland, 1967, MB, ChB
University of Glasgow, Scotland, 1976, PhD (Mathematical models of lung function)

Allan Pack | Nirinjini Naidoo | David Raizen | Sigrid Veasey