Publications Archive


Simpson NS, Banks S, Arroyo S, Dinges D. Effects of sleep restriction on adiponectin levels in healthy men and women. Sleep. 2010 Dec 2;101(5):693-8.

Greene RW, Frank MG. Slow wave activity during sleep: functional and therapeutic implications. Neuroscientist. 2010 Dec;16(6):618-33.

Goel N, Banks S, Mignot E, Dinges D. DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness and fatigue. Neurology. 2010 Oct 26;75(17):1509-19.

Brown MK, Naidoo N.The UPR and the anti-oxidant response: relevance to sleep and sleep loss. Molecular Neurobiology. 2010 Oct;42(2):103-13.

Gooneratne NS, Bellamy SL, Pack F, Staley B, Schutte-Rodin S, Dinges DF, Pack AI. Case-control study of subjective and objective differences in sleep patterns in older adults with insomnia symptoms. J Sleep Res. 2010 Sept 30[epub ahead of print].

McShane BB, Galante RJ, Jensen ST, Naidoo N, Pack AI, Wyner A. Characterization of the bout durations of sleep and wakefulness. J of Neurosci Methods. Nov 30;193(2):321-33.

Hanisch LJ, Gooneratne NS, Soin K, Gehrman PR, Vaughn DJ, Coyne JC. Sleep and daily functioning during androgen deprivation therapy for prostate cancer. Eur J Cancer Care (Engl). 2010 Sept 6[epub ahead of print].

Veasey S. Sleep homeostasis: finding Odysseus among the mnesteres. Sleep. 2010 Sept 1;33(9):1131-2.

Patel NP, Grandner MS, Xie D, Branas CC, Gooneratne NS. "Sleep disparity" in the population: poor sleep quality is strongly associated with poverty and ethnicity. BMC Public Health. 2010 Aug 11;10:475.

Banks S, Van Dongen HP, Maislin G, Dinges DF. Neurobehavioral dynamics following chronic sleep restriction: dose-response effects of one night for recovery. Sleep. 2010 Aug 1;33(8):1013-26.

Friedman EB, Sun Y, Moore JT, Hung HT, Meng QC, Perera P, Joiner WJ, Thomas SA, Eckinhoff RG, Sehgal A, Kelz MB. A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia. PLoS One. 2010 July 30;5(7)e11903.

Zheng X, Sehgal A. AKT and POR signaling set the pace of the circadian pacemaker. Curr Bio. 2010 July 13;13(20)1203-8.

Nikonova EV, Naidoo N, Zhang J, Romer M, Cater JR, Scharf MT, Galante RJ, Pack AI. Changes in components of energy regulation in mouse cortex with increases in wakefulness. Sleep.2010 July1;33(7):889-900.

Crocker A, Sehgal A. Genetic analysis of sleep. Genes Dev. 2010 June 15;24(12):1220-35.

Gooneratne NS, Patel NP, Corcoran A. Chronic obstructive pulmonary disease diagnosis and management in older adults. J Am Geriatr Soc. 2010 June;58(6):1153-62.

Calamaro CJ, Park S, Mason TB, Marcus CL, Weaver TE, Pack A, Ratcliffe SJ. Shortened sleep duration does not predict obesity in adolescents. J Sleep Res. 2010 June 2[epub ahead of print].

Crocker A, Shahidullah M, Levitan IB, Sehgal A. Identification of a neural circuit that underlies the effects of octopamine in sleep:wake behavior. Neuron 2010 Mar 11;65(5):670-81.

Oliveira AM, Hawk JD, Abel T, Havekes R. Post-training reversible inactivation of the hippocampus enhances novel object recognition memory. Learn Mem. 2010 Feb 26;17(3):155-60.

Veasey S. Treatment of obstructive sleep apnea. Indian J Med Res. 2010 Feb;131:236-44.

Wu MN, Joiner WJ, Dean T, Yue Z, Smith CJ, Chen D, Hoshi T, Sehgal A, Koh K. SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker. Nature Neurosci. 2010 Jan;13(10):69-75.


Vecsey CG, Baille G, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown K, Li X-Y, Descalzi G, Kim SS, Chen T, Shang Y-Z, Zhuo M, Houslay MD, Abel T.  Sleep deprivation impairs cAMP signaling in the hippocampus. Nature 2009. 461, 1122-1125.

Wu MN, Ho K, Crocker A, Yue Z, Koh K, Sehgal A. The effects of caffeine on sleep in Drosophila require PKA activity, but not the adenosine receptor. J Neurosci  2009, 29:11029-37.

Arnardottir ES, Mackiewicz M, Gislason T, Teff KL, Pack AI. Molecular signatures of obstructive sleep apnea in adults: a review and perspective. Sleep 2009 Apr 1;32(4):447-70. Review.

Naidoo N. ER and aging-protein folding and the ER stress response. Ageing Res Rev. 2009 July;8(3):150-9.

Naidoo N. Cellular stress/the unfolded protein response: Relevance to sleep and sleep disorders. Sleep Med Rev. 2009 Jun;13(3):195-204.

Pack AI, Gislasom T. Obstructive sleep apnea and cardiovascular disease a perspective and future directions. Prog Cardiovasc Dis. 2009 Mar-Apr;51(5):434-51.

Mackiewicz M, Zimmerman JE, Shockley KR, Churchill GA, Pack AI. What are microarrays teaching us about sleep? Trends Mol Med. 2009 Feb;15(2):79-87.

Veasey S. Insight from animal models into the cognnitive consequences of adult sleep-disordered breathing. ILAR J 2009;50(3):307-11

Aton SJ, Seibt J, Dumoulin M, Jha SK, Steinmetz N, Coleman T, Naidoo N, Frank MG. Mechanisms of sleep-dependent consolidation of cortical plasticity. Neuron. 2009 Feb 12;61(3):454-66.

Gehrman PR, Connor DJ, Martin JL, Shochat T, Corey-Bloom J, Ancoli-Israel S. Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease. Am J Geriatr Psychiatry. 2009 Feb;17(2):166-9.

Halassa MM, Florian C, Fellin T, Munoz JR, Lee SY, Abel T, Haydon PG, Frank MG. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron. 2009 Jan 29;61(2):213-9

Brennick MJ, Pack AI, Ko K, Kim E, Pickup S, Maislin G, Schwab RJ. Altered upper airway and soft tissue structures in the New Zealand Obese mouse. Am J Respir Crit Care Med. 2009 Jan 15;179(2):158-69.



Zimmerman JE, Raizen DM, Maycock MH, Maislin G, Pack AI. A video method to study Drosophila sleep. Sleep. 2008 Nov 1;31(11):1587-98.

Koh K, Joiner WJ, Wu MN, Yue Z, Smith CJ, Sehgal A. Identification of SLEEPLESS, a Sleep-Promoting Factor. Science 18 July 2008: Vol. 321. no. 5887, pp. 372-376, doi: 10.1126/ science.1155942

Schutte-Rodin S; Broch L; Buysse D; Dorsey C; Sateia M. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med 2008;4(5):487-504.

Pien GW, Samuel MD, Freeman, EW, Lin H, DeBlasis TL. Predictors of sleep quality in women in the menopausal transition. Sleep 2008;31(7):991-999.

Naidoo N, Ferber M, Master M, Zhu Y, Pack AI. Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling. J Neurosci. 2008 28: 6539-6548.

Zhu Y, Fenik P, Zhan G, Sanfillipo-Cohn B, Naidoo N, Veasey SC. Eif-2a protects brainstem motoneurons in a murine model of sleep apnea. J Neurosci. 2008 Feb 27;28(9):2168-78.

Kelz MB, Sun Y, Chen J, Cheng Meng Q, Moore JT, Veasey SC, Dixon S, Thornton M, Funato, H, Yanagisawa M. An essential role for orexins in emergence from general anesthesia. Proc Natl Acad Sci USA. 2008 Jan 29; 105(4):1309-14.

Bandla P, Huang J, Karamessinis L, Kelly A, Pepe M, Samuel J, Brooks L, Mason TA, Gallagher PR, Marcus CL. Puberty and Upper Airway Dynamics During Sleep. Sleep 2008;31(4):534-541.

Cuellar, NG and Ratcliffe, S. Restless Legs Syndrome in Type 2 Diabetes: Implications to Diabetes Educators. Diabetes Educator 2008, 34(2). (2.016).

Raizen D, Zimmerman J, Maycock M, Uyen DT, Young-jai Y, Sundaram MV, Pack AI. Lethargus is c. elegans sleep-like state. Nature. 2008 Jan 31;451(7178):569-72.



Zhu Y, Fenik P, Zhan G, Mazza E, Kelz M, Aston-Jones G, Veasey SC. Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model. J Neurosci. 2007 Sep 12;27(37):10060-71.

Mackiewicz M, Shockley KR, Romer MA, Galante RJ, Zimmerman JE, Naidoo N, Baldwin DA, Jensen ST, Churchill GA, Pack AI. Macromolecule biosynthesis - a key function of sleep. Physiol Genomics. 2007 Aug 14

Freeman EW, Sammel MD, Lin H, Gracia CR, Pien GW, Nelson DB, Sheng L. Symptoms associated with menopausal transition and reproductive hormones in midlife women. Obstet Gynecol. 2007 Aug;110(2 Pt 1):230-40

Weaver TE, Maislin G, Dinges DF, Bloxham T, George CF, Greenberg H, Kader G, Mahowald M, Younger J, Pack AI. Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep. 2007 Jun 1;30(6):711-9.

Castriotta RJ, Wilde MC, Lai JM, Atanasov S, Masel BE, Kuna ST. Prevalence and consequences of sleep disorders in traumatic brain injury. J Clin Sleep Med. 2007 Jun 15;3(4):349-56.

Naidoo N, Casiano V, Cater J, Zimmerman J, Pack AI. A role for the molecular chaperone protein BiP/GRP78 in Drosophila sleep homeostasis.Sleep. 2007 May 1;30(5):557-65.

Pack AI. Toward comprehensive interdisciplinary academic sleep centers. Sleep. 2007 Apr 1;30(4):383-4: discussion 385.



Ahmed MM, Schwab RJ. Upper airway imaging in obstructive sleep apnea. Curr Opin Pulm Med. 2006 Nov;12(6):397-401. Review.

Zimmerman JE, Rizzo W, Shockley KR, Raizen DM, Naidoo N, Mackiewicz M, Churchill GA, Pack AI. Multiple mechanisms limit the duration of wakefulness in Drosophila brain. Physiol Genomics. 2006 Nov 27;27(3):337-50.

Raizen DM, Mason TB, Pack AI. Genetic basis for sleep regulation and sleep disorders. Semin Neurol. 2006 Nov 26(5):467-83. Review.

Hartenbaum N, Collop N, Rosen IM, Phillips B, George CF, Rowley JA, Freedman N, Weaver TE, Gurubhagavatula I, Strohl K, Leaman HM, Moffitt GL, Rosekind MR. Sleep apnea and commercial motor vehicle operators: statement from the joint Task Force of the American College of Chest Physicians, American College of Occupational and Environmental Medicine, and the National Sleep Foundation. J Occup Environ Med. 2006 Sep;48(9 Suppl):S4-37. Review.

Schwab RJ. Controversy in surgical versus nonsurgical treatment of obstructive sleep apnea syndrome. J Oral Maxillofac Surg. 2006 Aug;64(8):1269-71.

Pack AI, Dinges DF, Gehrman PR, Staley B, Pack FM, Maislin G. Risk factors for excessive sleepiness in older adults. Ann Neurol. 2006 Jun;59(6):893-904.

Weinhouse GL, Schwab RJ. Sleep in the critically ill patient. Sleep. 2006 May 1;29(5):707-16. Review.

Lin SK, Kuna ST, Bogen DK. A novel device for measuring long-term oxygen therapy adherence: a preliminary validation. Respir Care. 2006 Mar;51(3):266-71.

Mackiewicz M, Nikonova EV, Zimmermann JE, Romer MA, Cater J, Galante RJ, Pack AI. Age-related changes in adenosine metabolic enzymes in sleep/wake regulatory areas of the brain. Neurobiol Aging. 2006 Feb;27(2):351-60.

Rosen IM, Gimotty PA, Shea JA, Bellini LM. Evolution of sleep quantity, sleep deprivation, mood disturbances, empathy, and burnout among interns. Acad Med. 2006 Jan;81(1):82-5.


Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ. Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep. 2005 Oct 1;28(10):1299-305.

Rosen IM. Driving while sleepy should be a criminal offense. J Clin Sleep Med. 2005 Oct 15;1(4):337-40.

Naidoo N, Giang W, Galante RJ, Pack AI. Sleep deprivation induces the unfolded protein response in mouse cerebral cortex. J Neurochem. 2005 Mar;92(5):1150-7.


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