CSCN 8th Annual Research Retreat
Friday, May 20, 2011
8:30 a.m. - 4:00 p.m., Reception to follow
Bodek Lounge, Houston Hall

Emmanuel Mignot


This year's keynote speaker will be Dr. Emmanuel Mignot, Professor of Psychiatry and Behavioral Sciences and Director of the Center for Narcolepsy at Stanford University. Dr. Mignot is internationally recognized as having discovered the cause of narcolepsy. He is also known for his discovery of a polymorphism of the CLOCK gene that appears to alter individuals' internal biological rhythms and for the finding of a gene variant that predisposes to sleep apnea.


2011 CSCN Research Retreat Schedule

7:45 - 8:15 a.m.  

Poster Mounting
Continental Breakfast will be served

8:20 - 8:30 a.m.  

Opening remarks
Allan I. Pack, Center Director

8:30 - 9:30 a.m.  

Session 1: Neural Mechanisms of Sleep and Wake


Mathieu Wimmer
" A novel approach to analyze age-related deterioration of sleep/wake in mice"


Miranda Lim
“Brain orexin levels predict wakefulness in a mouse model of traumatic brain injury”


Matthew D. Nelson
“Behavioral quiescence in C. elegans is regulated by the FRPamide europeptide encoding genes nlp-22 and -23


Jason T. Moore
“Sleep-active neurons in the ventrolateral preoptic nucleus are depolarized by clinically relevant doses of the general anesthetic isoflurane”

9:30 a.m.  


9:45 - 10:45 a.m.  

Session 2: Assessment and Consequences of Sleep Loss


Jason Gerstner
“Effects of acute sleep loss on dFabp expression and dFabp-induced long-term memory in Drosophila


Tzu-Hsing Kuo
“Recovery sleep enhances survival during bacterial infection in Drosophila


Bernie Sunwoo
“A Single Test to Assess Sleepiness by Objective Measures”


Hengyi Rao
“Effects of Sleep Deprivation on Neural Correlates of Risk-Taking”

10:45 a.m. - 12 n  

Session 3: Causes and Consequences of Disordered Sleep


Dorit Koren
“Sleep architecture and glucose and insulin homeostasis in obese adolescents”


Christopher Kim
“Relationship between upper airway collapsibility and the size of upper airway soft tissues in obese adolescents with OSAS and obese controls”


Cary B. Bearn
“Utility of mallampati and modified mallampati score in predicting the severity of obstructive sleep apnea in an obese population”


Ben Laitman
“╬▒-1 adrenoceptor antagonist prazosin reduces REM sleep (REMS) fragmentation and non-REM sleep (NREMS) latency in fear-conditioned Wistar-Kyoto rats (WKY)”

12:00n - 2:00 p.m.  

Poster Session and Lunch

2:00 - 3:00 p.m.  

Session 4: Genetics of Sleep and Sleep Mechanisms


Philip Gehrman
“Genome-wide association of insomnia phenotypes”


Ron Anafi
“Identification of Novel Core Clock Genes by Bayesian Integration”


John Zimmerman
“Genetic background has a major impact upon adaptation of sleep state to a changing environment┬áin Drosophila”


Namni Goel
“Circadian CLOCK T3111C polymorphism: role in response to sleep restriction”

3:00 - 4:00 p.m.  

Keynote address
“Immunology and Genetics of Narcolepsy”
Emmanuel Mignot, MD, PhD
Craig Reynolds Professor of Sleep Medicine

Professor of Psychiatry and Behavioral Sciences

University Center for Narcolepsy

4:00 - 5:00 p.m.  

Presentation Awards and Reception



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