Radioprotection of Curcumin via the NRF2 Pathway
mentored by Dr. Stephen Tuttle
NRF2 is required for curcumin-induced radioprotection.
:: Cell Culture.
:: Western Blot.
:: Quantitative Reverse Transcriptase PCR.
We demonstrated upregulation of inflammatory response genes (interleukin family, chemokines, tumor necrosis factor family) with radiation is reduced with curcumin diet compared to radiation alone.