| Projects > 2011 > Gabrielle James

The Effects of Acute Space Radiation on the Skin's Vasculature

Gabrielle James
mentored by Dr. Ann Kennedy and Dr. Jenine Sanzari.

Hypothesis
After irradiation similar to that of a solar particle event, skin toxicity will be observed and the vasculature will be altered.







Techniques
:: Large Animal Procedures.
:: Immunohistochemistry.
:: Microscopy.

Conclusions
The number of blood vessels in the dermis and the surface area of blood vessels decrease fourteen days after electron radiation exposure. Although statistical analyses result in no statistically significant difference between the pre-irradiated values and each time point (7, 14, and 30 days) evaluated, a trend is observed. Further experiments are necessary to confirm these findings.