CCETP Program Mentors

Program Mentors

Multidisciplinary clinical research training is best provided by teams of clinical scientists chosen based on the contributions they make to assist the trainees in answering important questions in their primary areas of interest. CCETP’s mentoring teams are led by preceptors (clinical epidemiologists) who serve as primary mentors and are participating faculty in the program. Additional members of the trainee mentoring teams include at least one content expert and at least one biostatistician.

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Aimin Chen penn

 

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Justin Bekelman, MD Meenakshi Bewtra, MD, MPH, PhD Aimin Chen, MD, PhD Angela DeMichele, MD, MSCE
Professor of Radiation Oncology, Medicine and Medical Ethics and Health Policy and Director of the Penn Center for Cancer Care Innovation (PC3I) Assistant Professor of Medicine and Epidemiology and a Senior Scholar in the CCEB Professor of Epidemiology and Associate Director of the Integrative Health Sciences Facility Core (IHSFC) in the NIEHS-funded Center of Excellence in Environmental Toxicology (CEET) Alan and Jill Miller Professor of Breast Cancer Excellence, Director of the Breast Cancer Trials Unit, and a CCETP graduate

 

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Jie Deng, PhD, RN Kojo Elenitoba-Johnson, MD Chris Feudtner, MD, PhD, MPH Alexander Fiks, MD, PhD, MPH
Associate Professor of Nursing, and Faculty Director of the Laboratory of Innovative and Translational Nursing Research at the School of Nursing Peter C. Nowell Professor of Pathology and Laboratory Medicine, and founding Director for the Center for Personalized Diagnostics Steven Handler Professor of Medical Ethics, Chief of the Division of General Pediatrics, Professor of Pediatrics, Medical Ethics and Health Policy, Director of the Department of Medical Ethics at CHOP, and Co-Director of the Pediatric Hospital Epidemiology and Outcomes Training Program Professor of Pediatrics and Distinguished Endowed Chair in Pediatrics at CHOP. He is also Director of the Center for Pediatric Clinical Effectiveness (CPCE) and Director of The Possibilities Project (Primary Care Innovation)

 

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Brian Fisher, DO, MSCE Kelly Getz, PhD, MPH James Guevara, MD, MPH Sean Hennessy, PharmD, PhD
Associate Professor of Pediatrics and Epidemiology, Senior Scholar in the CCEB, and Associate Chair of Research for the Department of Pediatrics Assistant Professor of Epidemiology and Director of the EPID 645: Cancer Epidemiology course Professor of Pediatrics and Epidemiology, a pediatric health services researcher and a practicing general pediatrician Professor of Epidemiology and of Systems Pharmacology and Translational Therapeutics, Director of the Center for Pharmacoepidemiology Research and Training (CPERT), PI of Penn’s T32 postdoctoral training program in clinical pharmacoepidemiology (T32GM075766), and a CCEB Senior Scholar

 

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Steven Joffe, MD, MPH Melanie Kornides, ScD, MPH, RN Bonnie Ky, MD, MSCE James Lewis, MD, MSCE
Interim Chair of the Department of Medical Ethics and Health Policy, the Art and Ilene Penn Professor of Medical Ethics and Health Policy and Professor of Pediatrics Assistant Professor in the Department of Family and Community Health at the School of Nursing and Assistant Professor (secondary appointment) of Pediatrics in the Division of Adolescent Medicine Founders Associate Professor of Cardio-Oncology in the Department of Medicine and the inaugural editor-in-chief of JACC: CardioOncology Professor of Medicine and Epidemiology, Director of the Gastroenterology and Hepatology Clinical Research Program (GHCRP), and Associate Director of the Inflammatory Bowel Disease (IBD) Program

 

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Ronac Mamtani, MD, MSCE David J. Margolis, MD, MSCE, PhD Stephanie Mayne, PhD, MHS Anne Marie McCarthy, PhD
Assistant Professor of Medicine in the Division of Hematology/Oncology and a member of the ACC and an MSCE graduate of the T32 training grant in Clinical Cancer Epidemiology Professor of Dermatology and Epidemiology, and Director of the Center for DermatoEpidemiology and Translation (CDET) in the Department of Dermatology Assistant Professor of Pediatrics and Associate Director for Epidemiology at the CHOP Center for Pediatric Clinical Effectiveness Assistant Professor of Epidemiology

 

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Shivan Mehta, MD, MPH, MSHP Sogol Mostoufi-Moab, MD, MSCE Katherine Nathanson, MD Katharine Rendle, PhD, MSW, MPH
Assistant Professor of Medicine and Health Policy and Associate Chief Innovation Officer at the Penn Medicine Center for Healthcare Innovation Associate Professor of Pediatrics and the Richard and Sheila Sanford Endowed Chair in Pediatric Oncology at CHOP Pearl Basser Professor of Medicine in the Division of Translational Medicine and Human Genetics, and Deputy Director of the Abramson Cancer Center (ACC) Director of Implementation Science at the Penn Center for Cancer Care Innovation (PC3I), and Assistant Professor of Family Medicine and Community Health and of Epidemiology (secondary)

 

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Marilyn Schapira, MD, MPH Lynn Schuchter, MD Lisa A. Schwartz, PhD Jeffrey H. Silber, MD, PhD
Professor of Medicine, Associate Director of the National Clinician Scholar Program, and Director of the General Internal Medicine Fellowship Program C. Willard Robinson Professor of Hematology/Oncology, and Chief of the Division of Hematology-Oncology Associate Professor of Pediatrics, psychologist for the Cancer Survivorship Program, behavioral scientist at the CHOP Center for Childhood Cancer Research, and co-Director of CHOP’s Mobile Health (mHealth) Research Affinity Group Nancy Abramson Wolfson Chair in Health Services Research at CHOP, Professor of Pediatrics and Anesthesiology & Critical Care at PSOM, and Professor of Health Care Management at The Wharton School

 

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David T. Teachey, MD Anil Vachani, MD, MSCE Kevin Volpp, MD, PhD Yu-Xiao Yang, MD, MSCE
Associate Professor of Pediatrics and Director of Clinical Research at the Center for Childhood Cancer Research at CHOP Associate Professor of Medicine and Director of Clinical Research for the Section of Interventional Pulmonology and Thoracic Oncology Vice Chair of Health Policy, Professor of Medicine, Professor of Health Care Management in Wharton, the founding Director of the Center for Health Incentives and Behavioral Economics (CHIBE) in the Leonard Davis Institute of Health Economics, and an ACC Member Associate Professor of Medicine and Epidemiology and a CCEB Senior Scholar

 

Content Experts 

Faculty who serve as content experts have clinical expertise in cancer, but may not be funded epidemiology researchers. They are selected jointly by the trainee and Drs. Aplenc and Glanz to match the trainee’s content area of focus. These faculty members provide content-specific advice, particularly clinical context, and serve as members of the trainee’s mentoring team. The content experts represent a wide range of cancer-related interests and are identified in the table below. Many other oncology faculty are also available to serve as Content Experts.

Exemplar Content Expert

Faculty and Appointment

Roles

Research Interests/Areas of Expertise

Rochelle Bagatell, MD,  Professor of Pediatrics (Oncology)

Director of CHOP’s Solid Tumor Program

Treatment of sarcomas and neuroblastoma

Frank Balis, MD, Louis and Amelia Canuso Family Endowed Chair for Clinical Research in Oncology, Professor of Pediatrics (Oncology)

Director, Clinical Cancer Research, Center for Childhood Cancer Research, CHOP

Development of new drugs and treatment strategies for childhood cancers, investigations of the pharmacology of anticancer drugs in children

Roger B. Cohen, MD, Professor of Medicine (Hematology-Oncology)

Fellowship Program Director, Hematology-Oncology; Associate Director of Clinical Research, ACC

Evaluation of novel therapies, including monoclonal antibodies, immune therapies, and small molecule cell-signaling pathway inhibitors

Emily Conant, MD, Professor of Radiology

Division Chief of Breast Imaging, Vice Chair of Radiology

Multi-modality breast imaging, breast cancer screening, high risk screening

Susan Domchek, MD, Basser Professor in Oncology

Executive Director, Basser Research Center; Director, MacDonald Women’s Cancer Risk Evaluation Center

Breast cancer risk and prevention, novel therapeutics particularly immune therapy, breast cancer genetics including BRCA

Michael Fisher, MD, Hubert J.P. and Anne Faulkner Schoemaker Endowed Chair in Pediatric Neuro-Oncology; Professor of Pediatrics

Director, Pediatric Neuro-oncology Program; Director, Neuro-oncology Fellowship

Neuro-oncology and neurofibramotosis

Jill Ginsburg, MD, Professor of Pediatrics (Oncology)

Director, Cancer Survivorship Program

Quality of life and the long-term consequences of cancer treatment

Stephan Grupp, MD PhD, Yetta Deitch Novotny Endowed Chair in Pediatric Oncology, Professor of Pediatrics (Oncology)

Co-PD for Pediatric Oncology, ACC; Director, Cancer Immunotherapy Program, CHOP

Engineered T cell and stem cell therapies, novel leukemia therapy

Stephen Hunger, MD, Jeffrey E. Perelman Distinguished Chair in Pediatrics, Professor of Pediatrics (Oncology)

Chief, Division of Oncology, CHOP

Director, Center for Childhood Cancer Research, CHOP

Acute lymphoblastic leukemia, relapsed acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), and hematologic malignancies

Despina Kontos, Matthew J. Wilson Associate Professor of Research Radiology

Associate Vice-Chair for Research, Department of Radiology

Biomedical image analysis; quantitative imaging biomarkers; pattern recognition;

Theodore Laetsch, MD, Associate Professor of Pediatrics (Oncology)

Head of Developmental Therapeutics Program and Very Rare Malignant Tumors Program, CHOP

Early phase clinical trials of new treatments for children with difficult to treat cancers

Alison Wakoff Loren, MD, MSCE, Professor of Medicine (Hematology-Oncology)

Director, Blood and Bone Marrow Transplantation

Allogeneic hematopoietic cell transplantation and hematologic malignancies

Selina Luger, MD, Professor of Medicine (Hematology-Oncology)

 

Clinical trials of novel therapeutic agents in patients with leukemia, myelodysplasia and other hematologic malignancies.

John M. Maris, MD, Professor of Pediatrics (Oncology)

Giulio D'Angio Chair in Neuroblastoma Research

Genomic, immunotherapeutic, and targeted molecular approaches to develop new treatment regimens from infants and children with neuroblastoma

Timothy Olson, MD, PhD, Assistant Professor of Pediatrics  (Oncology)

Director Blood and Marrow Transplant Program; Medical Director; Director of Research, Comprehensive Bone Marrow Failure Center

Pediatric hematopoietic stem cell transplantation  with emphasis for patients with inherited and acquired bone marrow failure

Peter Phillips, MD, Professor of Pediatrics (Oncology)

Director, Pediatric Neuro-oncology Program; Director, Neuro-oncology Fellowship;

Neuro-oncology and cellular mechanisms of neurotoxicity

David Porter, MD, Jodi Fisher Horowitz Professor in Leukemia Care Excellence, Professor of Medicine (Hematology-Oncology)

Director, Bone and Marrow Transplantation

Hematological malignancies, bone marrow and stem cell transplantation

Keith Pratz, MD, Associate Professor of Medicine (Hematology-Oncology)

Director of the Leukemia Program

Treatment of blood cancers, including acute myeloid leukemia and the myelodysplastic syndromes.

Mitchell Schnall, MD, PhD, Eugene P. Pendergrass Professor of Radiology, Chair of Radiology

PI, Penn PROSPR Research Center; Lung cancer screening

Translational biomedical and imaging research; comparative effectiveness

Stephen Schuster, MD, Robert and Margarita Louis-Dreyfus Associate Professor (Hematology-Oncology)

Director, Lymphoma Translational Research; CLL & Lymphoma Clinical Care and Research

Hematologic malignancies, lymphoma, myeloproliterative disease, high dose therapy, bone marrow transplant

Ursina Teitelbaum, MD, Deenie Greitzer and Daniel G. Haller Associate Professor of Medicine (Hematology-Oncology)

Leader, Pancreas Service Line

Gastrointestinal malignancies, colorectal cancer, pancreatic cancer, geriatric oncology

David Vaughn, MD, GU Medical Oncology Professor

Vice Chief for Clinical Affairs, Division of Hematology-Oncology

Development and testing of investigational agents in genitourinary cancers; cancer survivorship

 

Biostatisticians

The biostatisticians involved in CCETP have extensive experience in collaborative research, working with trainees, have methodological interests relevant tor cancer research, and some have their own funded research programs in methodological areas relevant to cancer. They provide biostatistics advice during all phases of the research project, particularly during the protocol development and data analysis.

 

Biostatistician and Appointment

Methodologic Interests/Areas of Application

Jinbo Chen, PhD, Professor of Biostatistics

Missing data methods, methods in genetic epidemiology, statistical genetics; development of breast cancer risk prediction model and collaborative studies of cancer epidemiology

Phyllis Gimotty, PhD, Professor of Biostatistics

Categorical and survival analysis, model assessment, classification trees, longitudinal data, evaluating diagnostic tests; cancer translational research, prevention and control, and risk assessment

Rebecca Hubbard, PhD,

Professor of Biostatistics

Statistical methodology for studies using observational data from community medical practice

Wei-Ting Hwang, PhD, Professor of Biostatistics

Statistical methods for survival and longitudinal data; applications of cancer research including breast, prostate, brain, and melanoma

Hongzhe Li, PhD, Perelman Professor of Biostatistics, Epidemiology, and Informatics

Methods for linking high-dimensional genomic data to censored survival outcomes such as time to cancer recurrence after treatment; and methods for integrative analysis of cancer genomic data in order to identify genes and pathways related to cancer initiation

Yimei Li, PhD, Assistant Professor of Biostatistics

Survival analyses, comparative effectiveness analyses in pediatric cancer populations

Qi Long, PhD, Professor of Biostatistics

Methods for analysis of big data (with application to -omics, electronic health records and mobile health data), predictive modeling, Bayesian modeling and methods, clinical trials, nonparametric and semi-parametric methods

Nandita Mitra, PhD, Professor of Biostatistics

Development of statistical methods for the analysis of population-based genetic association studies; extensive collaborations with investigators on various projects, including candidate gene and genome-wide association studies of testicular cancer, breast cancer, and prostate cancer

Jeffrey Morris, PhD, Professor of Biostatistics; Director, Biostatistics Division, DBEI

Constructing novel prognostic indices for hepatocellular carcinoma and helping develop and characterize molecular subtypes of colorectal cancer to discover new precision therapeutic strategies.

Mary Putt, PhD, ScD, Professor of Biostatistics

Functional data analysis of blood flow patterns in solid tumors during photodynamic therapy and the relationship with treatment efficacy, social determinants of differences in treatment and outcomes among cancer patients, biomarkers of cardiovascular dysfunction in breast cancer patients treated with chemotherapy

Paul Wileyto, PhD, Adjunct Professor of Biostatistics

Time-to-event and discrete data, including mixture models and repeated measures approaches; behavioral and imaging data arising from addiction research, particularly in tobacco use