Department of Psychiatry
Penn Behavioral Health

Translational Neuroscience Program

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Matthew R. Hayes, PhDMatthew R. Hayes, PhD
Assistant Professor of Nutritional Neuroscience
Associate Director, Translational Neuroscience Program
Lab Website:

Matt Hayes is an Assistant Professor of Nutritional Neuroscience, and Associate Director of the Translational Neuroscience Program in the Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania.  Dr. Hayes earned his Ph.D. in Nutritional Sciences from The Pennsylvania State University and conducted his postdoctoral fellowship in psychology and neuroscience at The University of Pennsylvania.  His current NIH-funded research examines the neuroendocrinology of energy balance control using rodent models.  In particular, the Hayes lab focusses their research efforts extensively on understanding the neural, behavioral, molecular, and physiological mechanisms by which hormones, such as glucagon-like peptide-1, amylin, and leptin regulate food intake and body weight through action in the mesolimbic reward system and caudal brainstem.  In addition to regulating food intake, the Hayes lab is also examining whether these neuroendocrine signaling pathways play a critical role in modulating drug taking and seeking using rodent models.  These basic science research efforts are conducted with the intention that they will translate into improved pharmacological / behavioral treatments for obesity, diabetes, drug abuse and co-morbid diseases.