The long-range goal of the Radiation Biology Research Program in the Department of Radiation Oncology at the University of Pennsylvania is to improve the outcome of cancer patients through an improved understanding of how ionizing and non-ionizing radiation interacts with biological tissues, as well as the fundamental process that dictate the pathogenesis, survival and death of cancer cells. Multiple investigators are brought together in this program to identify the molecular and physiological pathways influencing the response to treatment of tumors and normal tissues. Ongoing efforts are targeted at developing treatments and imaging approaches that can be used in clinical medicine to improve patient outcome. Our program is unique in the breadth and depth of the research available and in the wealth of collaborative activities, from molecular studies in gene expression and chromatin modifiers to translational projects involving animal models, as well as clinical trials. The research in the Radiation Biology Division is truly "bench-to-bedside". Current support for our research and educational goals includes 10 R01 grants, 2 Program Projects, and a T32 Training grant supported by the NIH. The National Space Biomedical Research Institute supports us as a Center of Acute Radiation Research and grants/contracts with the DOD and other government, academic and industrial sources further our research efforts. In all, the aggregate annual budget of this support totals over 10 million dollars. The Division has a dedicated administrative staff that manages these grants, as well as several lecture series that feature collaborators and renowned scientists from across the globe. Together with our Radiology collaborators, in recent years the Division has ranked Number 1 or 2 in National Institutes of Health grant funding among comparable programs in the country. We welcome you to click on any of the investigators below for more details of our ongoing research.
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