Partner Research Centers:

Institute on Aging

The IOA and CNDR Annual Research Retreat 2020

*IMPORTANT UPDATE: Due to the evolving situation surrounding COVID-19, the Institute on Aging (IOA) and Center for Neurodegenerative Disease Research (CNDR) will be postponing our Research Retreat scheduled for May 15, 2020. Please stay tuned for the new date.

"Bringing the Microscope to Clinic: Crossing the Translational Divide in Neurodegenerative Disease Research"

Details TBD

Presented by: The Institute on Aging and the Center for Neurodegenerative Disease Research (CNDR)

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Retreat Speakers

Keynote speakers: 
Leonard Petrucelli, PhD
Mayo Clinic, Jacksonville, FL
David A. Bennett, MD
Rush University

Penn presenters:
Todd Cohen
James Shorter
Silvia Porta
Aivi Nyguen
Paul Yushkevich
Fanny Leung
Les Shaw

Panel participants:
Leonard Petrucelli
David A. Bennett
Virginia M.-Y. Lee
John Trojanowski
Lauren Elman
David Wolk


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8:30 AM           


9:00 AM

An introduction to the new Annual IOA and CNDR Retreat

David J. Irwin, MD

9:05 AM


Robert Torres, PA Secretary of Aging

  AM Session: Mechanistic Studies of Neurodegeneration in Aging
9:15 AM Keynote: Leonard Petrucelli, PhD:
"Mechanisms of Tau and TDP-43 mediated neurodegeneration and therapeutic target strategies"
10:15 AM


10:30 AM

Basic Science Short Talks: Mechanisms of Protein Aggregation in Aging

10:30 am: Todd Cohen — "Post-translational modifications of ND proteins"
10:45 am: James Shorter — "Disaggregases in ND"
11:00 am: Silvia Porta — "Transmission of TDP-43"
11:15 am: Aivi Nyguen — "Single cell transcriptome of AD/TDP"

11:30 PM

LUNCH/POSTER SESSION — Interactive Datablitz (Basic Science)

  PM Session: Translational Human Studies of Neurodegenerative Disease
1:00 PM

Translational Short Talks: Antemortem Detection of Neurodegenerative Proteinopathies 

1:00 pm: Paul Yushkevich — "Histopathological guided imaging of ND proteins"
1:15 pm: Fanny Leung — "Identification of small RNA signatures for ADRD via high-throughput sequencing"
1:30 pm: Les Shaw — "Biofluid Biomarkers in ADRD"

1:45 PM

Keynote: David A. Bennett, MD:
"Heterogeneity of age-related pathologies in community dementia"

2:45 PM

Multidisciplinary Panel Discussion: "Speaking the same language: How to translate basic science discoveries and apply them to human patients"

Participants: Leonard Petrucelli, David A. Bennett, Virginia M.-Y. Lee, John Trojanowski, Lauren Elman, David Wolk, Moderator: David Irwin)

3:45 PM

Interactive Datablitz (Translational Posters)

4:45 PM




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The IOA and CNDR Research Retreat is free to attend, but registration is required. 

Registration opens April 20, 2020. 

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Poster Session

All poster submissions must include:

  • Poster title
  • Poster category (basic science, clinical research, or education & community)
  • Poster authors
  • Author affiliations
  • Abstract* (for Datablitz entry only)

Please note: Poster size is 3x5

For your chance to participate in our Datablitz session, you must submit a brief abstract to be reviewed by this year’s organizer, David J. Irwin, MD.
If selected, you will be given 5 minutes to present your findings to the event guests at our the poster session. 

Datablitz Submission deadline: April 15, 2020
Poster Submission deadline: May 8, 2020

Submit a poster now!


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Smilow Center for Translational Research
3400 Civic Center Boulevard  Philadelphia, PA 19104

The Smilow Center is adjacent to the Perelman Center for Advanced Medicine. 
Driving Directions and Parking Instructions can be found here.

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About the IOA and CNDR Annual Research Retreat

For almost 20 years, the Institute on Aging (IOA; directed by John Q. Trojanowski, MD, PhD) and the Center for Neurodegenerative Disease Research (CNDR; directed by Virginia M.-Y. Lee, PhD) have held separate annual research retreats. However, because of the close working relationship of the IOA and CNDR, their leadership, shared interests of the members of the IOA and CNDR, as well as the proliferation of Center and Institute retreats at Penn over the recent years, it was decided that the IOA and CNDR should join forces.

The goal is to synergistically combine the focus and themes of the IOA — all things related to aging — and CNDR — aging-related neurodegenerative diseases — and formally take advantage of the unique strengths in the IOA and CNDR to put forward a novel meeting concept. 

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A Recap of The 2019 Sylvan M. Cohen Annual Retreat + Poster Session