Faculty

Christina Twyman-Saint Victor, MD, MTR

faculty photo
Adjunct Assistant Professor of Medicine (Gastroenterology)
Department: Medicine

Contact information
3400 Civic Center Boulevard
Philadelphia, PA 19104
Education:
BS (Biology)
Duke University, 2002.
MD
Johns Hopkins Hospital, 2007.
MS (Translational Research)
University of Pennsylvania , 2016.
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Description of Clinical Expertise

General gastroenterology and endoscopy (e.g. EGD and colonoscopy)

Selected Publications

Wang J, Saung MT, Li K, Fu J, Fujiwara K, Niu N, Muth S, Wang J, Xu Y, Rozich N, Zlomke H, Chen S, Espinoza B, Henderson M, Funes V, Herbst B, Ding D, Twyman-Saint Victor C, Zhao Q, Narang A, He J, Zheng L.: CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma. J Exp Med. 219 (5), May 2022.

Rech AJ, Dada H, Kotzin JJ, Henao-Mejia J, Minn AJ, Twyman-Saint Victor C*, Vonderheide RH*: Radiotherapy and CD40 activation separately augment immunity to checkpoint blockade in cancer. Cancer Research 78(15): 4282-4291, August 2018 Notes: Epub 2018 May 29.2018

Benci JL, Xu B, Qiu Y, Wu TJ, Dada H, Twyman-Saint Victor C, Cucolo L, Lee DS, Pauken KE, Huang AC, Gangadhar TC, Amaravadi RK, Schuchter LM, Feldman MD, Ishwaran H, Vonderheide RH, Maity A, Wherry EJ, Minn AJ.: Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade. Cell 167(6), Dec 2016.

Tétreault MP, Weinblatt D, Ciolino JD, Klein-Szanto AJ, Sackey BK, Twyman-Saint Victor C, Karakasheva T, Teal V, Katz JP.: Esophageal Expression of Active IκB Kinase-β in Mice Up-Regulates Tumor Necrosis Factor and Granulocyte-Macrophage Colony-Stimulating Factor, Promoting Inflammation and Angiogenesis. Gastroenterology 150(7): 1609-1619, Jun 2016.

Twyman-Saint Victor C*, Rech AJ*, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ: Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 520(7547): 373-7, Apr 2015.

Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, Azzam DJ, Twyman-Saint Victor C, Wiemann BZ, Ishwaran H, Ter Brugge PJ, Jonkers J, Slingerland J, Minn AJ.: Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 159(3): 499-513, Oct 2014.

Babyatsky M, Lin J, Yio X, Chen A, Zhang JY, Zheng Y, Twyman C, Bao X, Schwartz M, Thung S, Lawrence Werther J, Itzkowitz S.: Trefoil factor-3 expression in human colon cancer liver metastasis. Clinical & Experimental Metastasis 26(2): 143-51, Nov 2009.

Zen Q, Batchvarova M, Twyman CA, Eyler CE, Qiu H, De Castro LM, Telen MJ. : B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease. Am J Hematol 75(2): 63-72, Feb 2004.

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Last updated: 01/10/2023
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