Description of CCEB Expertise

Dr. Margolis's research work is focused on DermatoEpidemiology and more specifically the epidemiology and treatment of chronic wounds. It is important to realize that more than 7 million Americans suffer from these wounds and the US spends more than $10 billion per year caring for individuals with these medical problems. He has been and is currently the Principal Investigator of several grants from NIH, FDA, AHRQ, industry, and foundations. These studies focus on chronic wounds (such as diabetic foot ulcers and venous leg ulcers). His contributions are important to our current understanding and practice regarding the design, choice of surrogate endpoints, and statistical analysis plan of studies addressing wound repair. The clinical assessments he innovated are now routinely incorporated into clinical trials designed to explore new treatments of venous legs and diabetic foot ulcers. Additional evidence of their importance is their incorporation into clinical treatment and evaluation guidelines used by insurers. He also has studies on the genetics of Atopic Dermatology, severe cutaneous drug eruptions, antibiotic use in acne, and the safety of therapy for dermatologic illnesses. His work focuses on epidemiologic study designs, comparative effectiveness designs and clinical trials. He is the founding director of the Center for DermatoEpidemilogy and Translation of the Perelman School of Medicine. He has published more than 175 scientific papers and frequently lectures at national and international meetings.

Description of Content-based Expertise

Aging, Cancer Epidemiology, Infectious Diseases, Patient-Oriented Research, Pharmacoepidemiology, Dermatology

Description of Methodology Expertise

Categorical Data, Clinical Trials, Diagnostic Testing, Meta-analysis