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Perelman School of Medicine at the University of Pennsylvania Advanced Search

Rexford S. Ahima, MD, PhD

Rexford S. Ahima, MD, PhD

faculty photo
Professor of Medicine
Department: Medicine

Contact information
Department of Medicine
Division of Endocrinology, Diabetes & Metabolism
12-104 Smilow Translational Research Center
3400 Civic Center Boulevard, Building 421
Philadelphia, PA 19104-6149
Office: (215) 573-1872
Fax: 215-746-8931
Lab: (215) 573-1874
B.Sc. (Endocrinology)
University of London, 1981.
University of Ghana Medical School, 1986.
Ph.D (Neuroscience)
Tulane University, New Orleans, LA, 1992.
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Description of Research Expertise

Research Interests:
Metabolic effects of circadian disruption
Role of lipid droplet proteins in lipid and glucose metabolism
Role of myokines in glucose and lipid metabolism
Brain insulin signaling and dementia

Key words: Brain, liver, adipose, adipokine, neuroendocrine, insulin, neuropeptide, obesity, diabetes.

Description of Research:
My laboratory is interested in central and peripheral regulation of energy homeostasis, and glucose and lipid metabolism. Adipokines, myokines, cytokines and other factors affect feeding, energy expenditure and glucose and lipid metabolism, through endocrine and paracrine signaling the brain and peripheral organs. Understanding these complex pathways may lead to better diagnostic and therapeutic tools for obesity, diabetes and other metabolic diseases.

1. Connecting leptin sensitivity and metabolism in feeding entrainment
2. Genetic determinants of leanness
3. Brain insulin signaling and dementia
4. Role of IPMK in glucose and lipid metabolism

Laboratory personnel:
Fred Anokye-Danso, PhD; Laboratory Manager; Technical Director of Penn Diabetes Research Center MPPM Core
Xiaoyan Yi, MD; Research Specialist, Penn Diabetes Research Center MPPM Core
Charles Addo-Yobo, BA; Technician, Penn Diabetes Research Center MPPM Core
Laura Scolaro, PhD; Postdoctoral fellow
Kyewon Park, PhD; Postdoctoral fellow
Phoebe Dacha, MD; Postdoctoral fellow
Erin Beacham; Penn School of Engineering
Doreen Agboh, BA; Research Scientist
Rotonya Carr, MD; Assistant Professor of Medicine

Description of Clinical Expertise

Endocrinology, Diabetes, Metabolism, Obesity

Description of Other Expertise

Metabolic phenotyping of mouse models of obesity, diabetes and dyslipidemia


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Last updated: 03/25/2016
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