Jeff E. Mandel, MD MS

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Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
Department of Anesthesiology & Critical Care
7 Dulles
3400 Spruce Street
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Office: 215-615-0553
Fax: 215-349-8133
BA (Biochemistry)
Rice University, 1976.
University of Texas Health Science Center at San Antonio, 1980.
MS (Engineering Sciences, Systems Science)
University of California, San Diego, 1985.
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Description of Research Expertise

Dr. Mandel has expertise in adaptive optimal control theory and pharmacokinetic modelling. He has conducted research in patient-controlled sedation.

Description of Clinical Expertise

Dr. Mandel specializes in anesthesia for otorhinolaryngologic procedures, particularly procedures of the trachea and larynx. He has special expertise in high frequency jet ventilation and total intravenous anesthesia. He has also been involved in developing new methods for sedation in GI endoscopy, interventional pulmonary procedures, and cardiac electrophysiology procedures.

Description of Other Expertise

Dr. Mandel has formal training in film and video production, and has produced video which has been presented at multiple national meetings.

Selected Publications

Mandel JE, Tietäväinen A, Otero J and Hæggström E: A simple posturographic method detects the di erence in recovery of patients receiving endoscopic sedation with propofol vs. midazolam. Medical Research and Innovations 1(2): 1-4, Apr 2017.

Atkins, JH, Haas, AR, Sterman, DH, Vachani, A, Mandel, JE: A randomized, placebo-controlled, concealed allocation comparison of respiratory depression during bronchoscopy with dexmedetomidine-ketamine as an adjunct to fentanyl-midazolam sedation. Transl Perioper & Pain Med 1(1): 1-8, Jan 2016.

Mandel JE, Atkins JH: Hilbert-Huang transform yields improved minute volume estimates from respiratory inductance plethysmography during transitions to paradoxical breathing Anesthesia & Analgesia 122(1): 126-31, Jan 2016.

Mandel Jeff E: Infusion systems: the infrastructure of modern anesthesia. Anesthesia and analgesia 120(6): 1178, Jun 2015.

Mountantonakis SE, Elkassabany N, Kondapalli L, Marchlinski FE, Mandel JE, Hutchinson MD: Provocation of atrial fibrillation triggers during ablation: does the use of general anesthesia affect inducibility? Journal of cardiovascular electrophysiology 26(1): 16-20, Jan 2015.

Mandel, JE: Application of pharmacokinetic and pharmacodynamic modeling to guide propofol administration for endoscopy procedures. Clinical Pharmacology for Anesthesiology. McGraw Hill, Page: 427-436, 2015.

Atkins JH, Mandel JE: Performance of Masimo rainbow acoustic monitoring for tracking changing respiratory rates under laryngeal mask airway general anesthesia for surgical procedures in the operating room: a prospective observational study. Anesthesia and analgesia 119(6): 1307-1314, Dec 2014.

Atkins JH, Mandel JE, Rosanova G: Safety and efficacy of drug-induced sleep endoscopy using a probability ramp propofol infusion system in patients with severe obstructive sleep apnea. Anesthesia and analgesia 119(4): 805-10, Oct 2014.

Tietäväinen A, Hæggström E, Mandel JE: Evaluation of postural steadiness before and after sedation: comparison of four nonlinear and three conventional measures. Physiological Measurement 35(2): 139, Feb 2014.

Mandel, Jeff E: Considerations for the use of short-acting opioids in general anesthesia. J Clin Anesthesia 26(1): S1-7, Jan 2014.

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Last updated: 04/25/2017
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