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Paris Margaritis, D.Phil

Paris Margaritis, D.Phil

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Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Rm 5024 Colket Translational Research Building
The Children's Hospital of Philadelphia
3501 Civic Center Blvd.
Philadelphia, PA 19104
Office: 2674267262
Fax: 2155903660
Lab: 2674267262
BSc (Hons) (Genetics)
The University of Newcastle-upon-Tyne (UK), 1995.
DPhil (Molecular Biology and Gene Therapy)
The University of Oxford (UK), 2000.
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Selected Publications

Pavani Giulia, Stafford Katherine, Margaritis Paris: Sequence determinants of mouse Protein C interaction with mouse Endothelial Protein C Receptor. American Society for Hematology Annual Meeting, San Francisco (CA), USA Dec 2014.

Connolly Courtney T., Faella Armida, Nichols Timothy C., High Katherine A., Arruda Valder R., Margaritis Paris: VKORc1 underexpression in skeletal muscle of humans, dogs, and mice: potential implications for ectopic coagulation factor expression in preclinical and therapeutic applications. American Society for Hematology Annual Meeting, San Francisco (CA), USA Dec 2014.

Elkouby Liron, Davidson Robert J., Margaritis Paris, High Katherine A., Sabatino Denise E. : Improved Factor VIII Expression with the Introduction of a PACE-Furin Variant into Codon-Optimized Human Factor VIII. American Society for Hematology Annual Meeting, San Francisco (CA), USA Dec 2014.

Nanaware-Kharade N., Gonzalez III G.A., Reichard E. E., Wolf S., Margaritis P., Peterson E. C.: Using Adeno-Associated Virus (AAV) Mediated Sustained Expression of an Anti- methamphetamine Antibody Fragment to Alter Methamphetamine Disposition in Mice. American Association of Pharmaceutical Scientists Annual Meeting, San Diego (USA) Nov 2014.

Pavani Giulia, Ivanciu Lacramioara, Faella Armida, Marcos-Contreras Oscar A. and Margaritis Paris: The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo. Blood 124(7): 1157-65, Aug 2014.

Pavani Giulia, Ivanciu Lacramioara, Faella Armida, Marcos-Contreras Oscar O., Margaritis Paris: Binding of FVIIa to the endothelial Protein C receptor enhances its hemostatic function in hemophilic mice Thrombosis and Hemostasis Summit of North America meeting, Chicago (USA) Apr 2014.

Margaritis Paris: Does rFVIIa work solo in hemophilia? Blood 123(11): 1631-1633, Mar 2014.

Balestra Dario, Faella Armida, Margaritis Paris, Cavallari Nicola, Pagani Franscesco, Bernardi Franscesco, Arruda Valder R., Pinotti Mirko: An engineered U1 small nuclear RNA rescues splicing-defective coagulation F7 gene expression in mice. Journal of Thrombosis and Haemostasis 12(2): 177-85, Feb 2014.

Yazicioglu Mustafa N., Monaldini Luca, Chu Kirk, Khazi Fayaz R., Murphy Samuel L., Huang Heshu, Margaritis Paris, High Katherine A.: Cellular Localization and Characterization of Cytosolic Binding Partners for Gla-containing Proteins PRRG4 and PRRG2. Journal of Biological Chemistry Sep 2013.

Crudele Julie M, Van Sluis Geerte L., Margaritis Paris, Siner Joshua I., Mauer Jenna, Faella Armida, Zhou Shangzhen, Esmon Charles T., High Katherine A., Spek Arnold C., Arruda Valder R.: Mechanistic insights into zymogen protein C protection against cancer progression. International Society of Thrombosis and Haemostasis meeting, Amsterdam, The Netherlands. Jul 2013.

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Last updated: 02/10/2015
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