Kirk J Wangensteen, MD, PhD

faculty photo
Assistant Professor of Medicine
Department: Medicine
Graduate Group Affiliations

Contact information
Division of Gastroenterology
421 Curie Boulevard, BRB 910
Philadelphia, PA 19104
Office: 2155737314
Fax: 2158980573
BA (Biological Sciences)
Northwestern University, 2000.
PhD (Biochemistry, Molecular Biology, and Biophysics)
University of Minnesota, 2007.
MD (Medicine)
University of Minnesota, 2009.
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Description of Clinical Expertise

Kirk Wangensteen, MD/PhD specializes in Gastroenterology and Hepatology and his clinical expertise includes genetic diseases of the gastrointestinal tract, pancreas, and liver.

Description of Research Expertise

Kirk Wangensteen, MD/PhD's research expertise includes liver biology and genetics. In particular, he is mapping the genetic pathways that enable liver regeneration and cause liver cancer. He has set up innovative in vivo screening systems to elucidate these pathways in a mouse model of liver injury and repopulation.

Selected Publications

Huasheng Yu, Kirk Wangensteen, Tong Deng, Yulong Li, Wenqin Luo: MRGPRX4 in Cholestatic Pruritus. Seminars in Liver Disease 41(3): 358-367, Aug 2021.

Bryson Katona, Jessica Long, Nuzhat Ahmad, Sara Attalla, Angela Bradbury, Erica Carpenter, Dana Clark, Gillain Constantino, Koushik Das, Susan Domchek, Christina Dudzik, Jessica Ebrahimzadeh, Gregory Ginsberg, Jordan Heiman, Michael Kochman, Kara Maxwell, Danielle McKenna, Jacquelyn Powers, Payal Shah, Kirk Wangensteen, and Anil Rustgi: EUS-based pancreatic cancer surveillance in BRCA1/BRCA2/PALB2/ATM carriers without a family history of pancreatic cancer. Cancer Prevention Research Aug 2021 Notes: Online ahead of print.

Anya Mezina, Neil Philips, Zoe Bogus, Noam Erez, Rui Xiao, Ruoming Fan, Kim M. Olthoff, K. Rajender Reddy, N. Jewel Samadder, Sarah M. Nielsen, Kathryn E. Hatchell, Edward D. Esplin, Anil K. Rustgi, Bryson W. Katona, Maarouf A. Hoteit, Katherine L. Nathanson, Kirk J. Wangensteen: Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants. JCO precision oncology(5), 988-1000, Jun 2021.

Ricciotti, Emanuela, Wangensteen, Kirk J., FitzGerald, Garret A.: Aspirin in hepatocellular carcinoma. Cancer Res April 2021 Notes: Online ahead of print.

Wangensteen KJ, Chang KM.: Multiple Roles for Hepatitis B and C Viruses and the Host in the Development of Hepatocellular Carcinoma. Hepatology 73: 27-37, Jan 2021.

Kumar S, Dudzik CM, Reed M, Long JM, Wangensteen KJ, Katona BW.: Upper Endoscopic Surveillance in Lynch Syndrome Detects Gastric and Duodenal Adenocarcinomas. Cancer Prev Res (Phila) 13: 1047-1054, Dec 2020.

Yin Dingzi, Wang Amber W, Erez Noam, Wangensteen Kirk J: An in vivo dropout CRISPRi screen for regulators of liver regeneration. Hepatology November 2020 Notes: Poster at the AASLD Liver Meeting Digital Experience.

Yin Dingzi, Erez Noam, Wangensteen Kirk J: A pooled in vivo CRISPRi screen identifies synthetic lethal partners of MYC in hepatocellular carcinoma development. Hepatology November 2020 Notes: Oral presentation at the AASLD Liver Meeting Digital Experience.

Yin Dingzi and Wangensteen Kirk J: Incapacitated Capicua in Sorafenib-Resistant HCC. Cell Mol Gastroenterol Hepatol 10(2): 428-429, Apr 2020.

Zahm Adam M, Wang Amber W, Wang Yue J, Schug Jonathan, Wangensteen Kirk J*, Kaestner Klaus H*: A High-Content Screen Identifies MicroRNAs That Regulate Liver Repopulation After Injury in Mice. Gastroenterology 158(4): 1044-1057 e17, Mar 2020 Notes: *co-corresponding.

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Last updated: 08/08/2021
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