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Mark E. Mikkelsen, MD, MSCE

Mark E. Mikkelsen, MD, MSCE

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Gates 05042
3400 Spruce Street
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Office: (215) 615-5416
Fax: (215) 614-0869
Lab: (267) 285-6602
BA (Political Science)
Colgate University, Hamilton, NY, 1996.
(Post-Baccalaureate Pre-Medical Degree Program)
Bryn Mawr College, Bryn Mawr, PA, 1997.
MD (Medical Degree)
University of Virginia School of Medicine, Charlottesville, VA, 2002.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, Philadelphia, PA, 2008.
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Description of Research Expertise

Through the lens of the patient and their family, Dr. Mikkelsen conducts patient-oriented research focused on sepsis, acute respiratory distress syndrome, and long-term outcomes in survivors of critical illness. He is passionate in his goal to improve the delivery of care to critically ill patients and to improve the lives of survivors of critical illness by understanding how critical illness impacts one's life and one's health trajectory.

Dr. Mikkelsen encourages colleagues, as well as survivors of critical illness and their loved ones, who are committed to improving the quality of care delivered to critically ill patients to contact him at mark.mikkelsen@uphs.upenn.edu. Together, we can "be the difference."

Health services research
Quality Improvement/Implementation and Dissemination Research
Critical Care Delivery
Long-Term Outcomes of Critical Illness

Description of Clinical Expertise

Dr. Mikkelsen's philosophy for patient care is to ensure that exceptional, compassionate care is delivered to critically ill patients and their family members through outstanding, multi-disciplinary teamwork across the continuum of care, through the application of evidence-based care, and through systematic study to optimize our performance. Dr. Mikkelsen is an expert in critical care medicine, and the devastating syndromes of sepsis, acute respiratory distress syndrome, and post-intensive care syndrome specifically.

Critical Care Delivery
Quality Improvement
Post-Intensive Care Syndrome
Long-Term Outcomes of Critical Illness

Selected Publications

Maley JH, Siruckova R, McGraw KA, Brewster I, Mayoral I, Adams S, Piech AA, Mikkelsen ME: Post-intensive care syndrome, resilience, and health-related quality of life in survivors of critical illness. Crit Care Med 2016 Notes: Accepted abstract.

Mikkelsen ME, Jackson JC, Hopkins RO, Thompson C, Andrews A, Netzer G, Bates DM, Bunnell AE, Christie LM, Greenberg SB, Lamas DJ, Sevin CM, Weinhouse G, Iwashyna TJ: Peer support as a novel strategy to mitigate post-intensive care syndrome. Advanced Crit Care 2016 Notes: In press.

Price D, Mikkelsen ME, Umscheid CA, Armstrong E: Neuromuscular blocking agents and neuromuscular dysfunction acquired in critical illness: a systematic review and meta-analysis. Crit Care Med 2016 Notes: In press.

Oppenheim I, Atkins J, Mikkelsen ME, Gittleman E, Choi, Leri D, Fuchs BD: Implementation of an extubation risk screening and planning protocol to improve airway safety. Crit Care Med 2016 Notes: Accepted abstract.

Maley JH, Mikkelsen ME: Sepsis survivorship: how can we promote a culture of resilience? Crit Care Med 43(2): 479-481, 2015 Notes: Editorial.

Mikkelsen ME, Iwashyna TJ: Persistent problems and recovery after critical illness. Oxford Textbook of Medicine 6th Edition. Simon Finfer (eds.). 2015 Notes: Accepted chapter.

Mikkelsen ME, Lanken PN, Christie JD : Acute lung injury and the acute respiratory distress syndrome. Principles of Critical Care. 4th Edition. Jesse Hall, Gregory Schmidt, Lawrence Wood (eds.). (eds.). McGraw Hill, 2015 Notes: Chapter. In press.

Mikkelsen ME, Fuchs BD, Grippi MA: Organization of intensive care units and long term acute care hospitals (LTACHs). Fishman's Pulmonary Diseases and Disorders, 5th ed. Grippi M, Elias J, Fishman J, Kotloff R, Pack A, Senior R, eds. (eds.). New York: McGraw-Hill, 2015 Notes: Chapter. In press.

Ortego A, Gaieski DF, Fuchs BD, Jones T, Halpern SD, Small DS, Sante SC, Drumheller B, Christie JD, Mikkelsen ME: Hospital-based acute care use in survivors of septic shock. Crit Care Med 43(4): 729-737, 2015.

Whittaker SA, Fuchs BD, Gaieski DF, Christie JD, Goyal M, Meyer NJ, Kean C, Small DS, Bellamy SL, Mikkelsen ME: Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards. J Crit Care 30(1): 78-84, 2015.

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Last updated: 02/09/2016
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