Samuel Swisher-Mcclure, M.D., M.S.H.P.

faculty photo
Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology

Contact information
3400 Civic Center Boulevard, TRC2 West
Department of Radiation Oncology
Philadelphia, PA 19104
Office: 215-220-9460
Fax: 215-349-5445
BA (English Literature)
Middlebury College, 2000.
MD (Medicine)
West Virginia University School of Medicine, 2007.
MSHP (Health Policy Research)
Perelman School of Medicine at the University of Pennsylvania, 2014.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Clinical Expertise

Dr. Swisher-McClure's clinical practice is focused on the multidisciplinary management of patients with thoracic and head and neck malignancies.

Description of Other Expertise

Dr. Swisher-McClure previously served as the residency program director for the Department of Radiation Oncology from 2013-2020. He is the current associate medical director for the Roberts Proton Therapy Center.

Description of Research Expertise

Samuel Swisher-McClure, MD MSHP is an Assistant Professor of Radiation Oncology at the University of Pennsylvania. He conducts oncology related health services research, and clinical trials focused on toxicity reduction for patients with Head and Neck Cancer.

Selected Publications

Mohiuddin Jahan J, Chu Brian, Facciabene Andrea, Poirier Kendra, Wang Xingmei, Doucette Abigail, Zheng Cathy, Xu Wei, Anstadt Emily J, Amaravadi Ravi K, Karakousis Giorgos C, Mitchell Tara C, Huang Alexander C, Shabason Jacob E, Lin Alexander, Swisher-McClure Samuel, Maity Amit, Schuchter Lynn M, Lukens John N: Association of antibiotic exposure with survival and toxicity in patients with melanoma receiving immunotherapy. Journal of the National Cancer Institute Apr 2020.

LaRiviere Michael J, Santos Patricia Mae G, Jones Joshua A, Lukens John Nicholas, Vapiwala Neha, Swisher-McClure Samuel D, Berman Abigail T: Introducing Multidisciplinary Oncology Management to the Medical Student. Advances in radiation oncology 5(2): 289-291, Mar-Apr 2020.

Diffenderfer Eric S, Verginadis Ioannis I, Kim Michele M, Shoniyozov Khayrullo, Velalopoulou Anastasia, Goia Denisa, Putt Mary, Hagan Sarah, Avery Stephen, Teo Kevin, Zou Wei, Lin Alexander, Swisher-McClure Samuel, Koch Cameron, Kennedy Ann R, Minn Andy, Maity Amit, Busch Theresa M, Dong Lei, Koumenis Costas, Metz James, Cengel Keith A: Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System. International journal of radiation oncology, biology, physics 106(2): 440-448, Feb 2020.

Frick Melissa A, Feigenberg Steven J, Jean-Baptiste Samuel R, Aguarin Louise A, Mendes Amberly, Chinniah Chimbu, Swisher-McClure Samuel, Berman Abigail, Levin William, Cengel Keith, Hahn Stephen M, Dorsey Jay F, Simone Charles B, Kao Gary D: Circulating tumor cells are associated with recurrent disease in patients with early stage non-small cell lung cancer treated with stereotactic body radiation therapy. Clinical cancer research : an official journal of the American Association for Cancer Research Jan 2020.

Weinstein, G. S., Cohen, R., Lin, A., O'Malley, B. W., Jr., Lukens, J., Swisher-McClure, S., Shanti, R. M., Newman, J. G., Parhar, H. S., Tasche, K., Brody, R. M., Chalian, A., Cannady, S., Palmer, J. N., Adappa, N. D., Kohanski, M. A., Bauml, J., Aggarwal, C., Montone, K., Livolsi, V., Baloch, Z. W., Jalaly, J. B., Cooper, K., Rajasekaran, K., Loevner, L., Rassekh, C.: Penn Medicine Head and Neck Cancer Service Line COVID-19 management guidelines. Head Neck 42(7): 1507-1515, 2020.

Hague, C., Aznar, M., Dong, L., Fotouhi-Ghiam, A., Lee, L. W., Li, T., Lin, A., Lowe, M., Lukens, J. N., McPartlin, A., O'Reilly, S., Slevin, N., Swisher-Mcclure, S., Thomson, D., Van Herk, M., West, C., Zou, W., Teo, B. K.: Inter-fraction robustness of intensity-modulated proton therapy in the post-operative treatment of oropharyngeal and oral cavity squamous cell carcinomas. Br J Radiol 93(1107): 20190638, 2020.

Borja, A. J., Hancin, E. C., Dreyfuss, A. D., Zhang, V., Mathew, T., Rojulpote, C., Werner, T. J., Patil, S., Gonuguntla, K., Lin, A., Feigenberg, S. J., Swisher-McClure, S., Alavi, A., Revheim, M. E.: (18)F-FDG-PET/CT in the quantification of photon radiation therapy-induced vasculitis. Am J Nucl Med Mol Imaging 10(1): 66-73, 2020.

Mante, A., Hawrot, K., Bvochora-Nsingo, M., Chiyapo, S., Balang, D., Barg, F., Baffic, C., Monare, B., Vapiwala, N., Ralefala, T., Metz, J., Swisher-McClure, S., Grover, S.: Radiation Oncology Rotation in Botswana: Resident Experience and Career Interests. Int J Radiat Oncol Biol Phys 107(4): 850-852, 2020.

Swisher-McClure Samuel, Lukens John N, Aggarwal Charu, Ahn Peter, Basu Devraj, Bauml Joshua M, Brody Robert, Chalian Ara, Cohen Roger B, Fotouhi-Ghiam Alireza, Geiger Geoffrey, Gershowitz Jared, Livolsi Virginia, Mitra Nandita, Montone Kathleen, Newman Jason, Ojerholm Eric, O'Malley Bert, Rajasekaran Karthik, Tan Erik, Weinstein Gregory, Lin Alexander: A Phase II Trial of Alternative Volumes of Oropharyngeal Irradiation for De-intensification (AVOID): Omission of the Resected Primary Tumor Bed Following Transoral Robotic Surgery for Human Papilloma Virus Related Squamous Cell Carcinoma of the Oropharynx. International journal of radiation oncology, biology, physics Nov 2019.

Gershowitz Jared, Chao Hann-Hsiang, Doucette Abigail, Lukens John N, Swisher-McClure Samuel, Weinstein Gregory S, O'Malley Bert W, Chalian Ara A, Rassekh Christopher H, Newman Jason G, Cohen Roger B, Bauml Joshua M, Aggarwal Charu, Lin Alexander: Risk of Post-Operative, Pre-Radiotherapy Contralateral Neck Recurrence in Patients Treated with Surgery Followed by Adjuvant Radiotherapy for Human Papilloma Virus-Associated Tonsil Cancer. The British journal of radiology 92(1104): 20190466, Oct 2019.

back to top
Last updated: 10/30/2020
The Trustees of the University of Pennsylvania