Ebenezer Daniel, MBBS, MS, DO, MPH, PhD

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Assistant Professor of Ophthalmology at the Hospital of the University of Pennsylvania
Director, Ophthalmology Reading Center, Scheie Eye Institute, University of Pennsylvania
Instructor in Ophthalmology, University of Pennsylvania
Department: Ophthalmology

Contact information
Ophthalmology Reading Center
Department of Ophthalmology
University of Pennsylvania
3711 Market Street, Suite 801,Rm 820
Philadelphia, PA 19104
Office: 2156151523
Fax: 2156151533
MBBS (Undergraduate Medicine)
Christian Medical College, Vellore, India, 1980.
DO (Diploma in Ophthalmology)
Joseph Eye Hospital, Trichy, India, 1984.
MS (Master of Surgery in Ophthalmology)
Madras Medical College, Tamilnadu, India, 1987.
MPH (Internation Health and Public Health in Ophthalmology)
Johns Hopkins School of Public Health, 2001.
PhD (Ophthalmology)
MGR Medical University, Chennai, India, 2010.
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Description of Clinical Expertise

Expertise in Ocular Leprosy. Extensive experience of more than 14 years in diagnosing and treating ocular complications in leprosy patients. Been involved in extensive research in ocular leprosy including being the principal investigator of the WHO sponsored study on longitudinal study of ocular leprosy (LOSOL). Published a number of peer reviewed articles on ocular leprosy and written a chapter on ocular leprosy in a textbook on the disease. Trained local, national and international ophthalmologists and physicians in oculo-plastic surgery and in the treatment of common ocular complications occurring in leprosy. Give lectures on eye manifestations and treatment of ocular leprosy at the biannual seminar on Hansen's disease held at the Gillis National Hansen's disease center in Baton Rouge, Louisiana every year.

Description of Research Expertise

Directing an Ophthalmology Reading Center. Organizing and executing studies that require the services of a centralized reading center in grading digital retinal images of various retinal diseases including age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity. Developing grading forms and grading protocols and training non-physician readers to accurately and consistently grade retinal pathology in clinical trials.

Selected Publications

Daniel Ebenezer, Quinn Graham E, Hildebrand P Lloyd, Ells Anna, Hubbard G Baker, Capone Antonio, Martin E Revell, Ostroff Candace P, Smith Eli, Pistilli Maxwell, Ying Gui-Shuang: Validated System for Centralized Grading of Retinopathy of Prematurity: Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study. JAMA Ophthalmol 133(6): 675-82, Mar 2015.

Daniel, Ebenezer. Toth, Cynthia A. Grunwald, Juan E. Jaffe, Glenn J. Martin, Daniel F. Fine, Stuart L. Huang, Jiayan. Ying, Gui-shuang. Hagstrom, Stephanie A. Winter, Katrina. Maguire, Maureen G. Comparison of Age-related Macular Degeneration Treatments Trials Research Group.: Risk of scar in the comparison of age-related macular degeneration treatments trials. Ophthalmology 121(3): 656-66, Mar 2014.

Grunwald, Juan E. Daniel, Ebenezer. Huang, Jiayan. Ying, Gui-Shuang. Maguire, Maureen G. Toth, Cynthia A. Jaffe, Glenn J. Fine, Stuart L. Blodi, Barbara. Klein, Michael L. Martin, Alison A. Hagstrom, Stephanie A. Martin, Daniel F. CATT Research Group.: Risk of geographic atrophy in the comparison of age-related macular degeneration treatments trials. Ophthalmology 121(1): 150-61, Jan 2014.

Daniel, Ebenezer. Pistilli, Maxwell. Pujari, Siddharth S. Kacmaz, R Oktay. Nussenblatt, Robert B. Rosenbaum, James T. Suhler, Eric B. Thorne, Jennifer E. Foster, C Stephen. Jabs, Douglas A. Levy-Clarke, Grace A. Kempen, John H.: Risk of hypotony in noninfectious uveitis. Ophthalmology 119(11): 2377-85, Nov 2012.

Grunwald, Juan E. Daniel, Ebenezer. Ying, Gui-Shuang. Pistilli, Maxwell. Maguire, Maureen G. Alexander, Judith. Whittock-Martin, Revell. Parker, Candace R. Sepielli, Krista. Blodi, Barbara A. Martin, Daniel F. CATT Research Group.: Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 119(8): 1634-41, Aug 2012.

Kempen, John H. Daniel, Ebenezer. Dunn, James P. Foster, C Stephen. Gangaputra, Sapna. Hanish, Asaf. Helzlsouer, Kathy J. Jabs, Douglas A. Kacmaz, R Oktay. Levy-Clarke, Grace A. Liesegang, Teresa L. Newcomb, Craig W. Nussenblatt, Robert B. Pujari, Siddharth S. Rosenbaum, James T. Suhler, Eric B. Thorne, Jennifer E.: Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive drugs: retrospective cohort study. BMJ 339: b2480, Jul 2009.

Daniel, Ebenezer. Sundar Rao, P S S.: Evolution of vision reducing cataract in skin smear positive lepromatous patients: does it have an inflammatory basis?. British Journal of Ophthalmology 91(8): 1011-3, Aug 2007.

Daniel, E. Ffytche, T J. Sundar Rao, P S S. Kempen, J H. Diener-West, M. Courtright, P.: Incidence of ocular morbidity among multibacillary leprosy patients during a 2 year course of multidrug therapy. British Journal of Ophthalmology 90(5): 568-73, May 2006.

Daniel, E. Ffytche, T J. Kempen, J H. Rao, P S S Sundar. Diener-West, M. Courtright, P.: Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy. British Journal of Ophthalmology 90(8): 949-54, Aug 2006.

Ebenezer Daniel: Ocular Leprosy. IAL Textbook of Leprosy. 2nd Edition. Kumar Bhushan, Kar Hemanta Kumar (eds.). Jaypee Brothers Medical Publishers Pvt. Ltd.New Delhi 2016.

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Last updated: 07/18/2022
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