Bryan L Krock, PhD

faculty photo
Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Boulevard, RM 706B ARC Bldg.
Philadelphia, PA 19104
Office: 267-426-7588
Fax: 215-590-2156
Education:
BS (Biology)
Pennsylvania State University, 2003.
PhD (Biology)
Texas A&M University, 2009.
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Selected Publications

Carolien G. F. de Kovel, PhD1,2; Steffen Syrbe, MD, PhD3; Eva H. Brilstra, MD, PhD1; Nienke Verbeek, MD, PhD1; Bronwyn Kerr, PhD4,5,6; Holly Dubbs, MD7; Allan Bayat, MD, PhD8; Sonal Desai, MGC, CGC9; Sakkubai Naidu, MD10,11; Siddharth Srivastava, MD12; Hande Cagaylan, MD13; Uluc Yis, MD, PhD14; Carol Saunders, PhD15,16,17; Martin Rook, PhD18; Susanna Plugge, MSc19; Hiltrud Muhle, MD20; Zaid Afawi, MD, PhD21; Karl-Martin Klein, MD, PhD22; Vijayakumar Jayaraman, MSc23; Ramakrishnan Rajagopalan, PhD23; Ethan Goldberg, MD, PhD7; Eric Marsh, MD, PhD7; Sudha Kessler, MD, MSCE7; Christina Bergqvist, MD7; Laura K. Conlin, PhD23; Bryan L. Krock, PhD23; Isabelle Thiffault, PhD15,16; Manuela Pendziwiat, MSc20; Ingo Helbig, MD7,24; Tilman Polster, MD, PhD25; Ingo Borggraefe, MD, PhD26; Johannes R. Lemke, MD, PhD27; Marie-José van den Boogaardt, MD, PhD1; Rikke S. Møller, MSc, PhD8,28; Bobby P. C. Koeleman, PhD1: Neurodevelopment Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes. JAMA Neurology August 2017.

Gade TPF, Tucker E, Nakazawa MS, Hunt SJ, Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, Furth EE, Winkler JD, Amaravadi RK, Simon MC: Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Radiology 283(3): 702-710, March 2017.

Abou Tayoun Ahmad N, Krock Bryan, Spinner Nancy B: Sequencing-based diagnostics for pediatric genetic diseases: progress and potential. Expert Rev Mol Diagn 17: 1-13, Aug 2016.

Mundy SA, Krock BL, Mao R, Shen JJ: BRAT1-related disease-identification of a patient without early lethality. Am J Med Genet A 170(3): 699-702, Mar 2016.

Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. : Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration Acta Neuropathol 130(3): 363-72, Sep 2015.

Viktor Lukacs, Jayani Mathur, Rong Mao, Pinar Bayrak-Toydemir, Melinda Procter, Stuart M. Calahan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day, David A Stevenson, Ardem Patapoutian, Bryan L. Krock: Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. Nat Commun 6: 8329, Sep 21 2015.

Krock BL, Eisinger-Mathason TS, Giannoukos DN, Shay JE, Gohil M, Lee DS, Nakazawa MS, Sesen J, Skuli N, Simon MC.: The aryl hydrocarbon receptor nuclear translator is an essential regulator of murine hematopoietic stem cell viability. Blood 125(21): 3263-72, May 2015.

Leoni Chiara, Stevenson David A, Geiersbach Katherine B, Paxton Christian N, Krock Bryan L, Mao Rong, Rope Alan F: Neural tube defects and atypical deletion on 22q11.2. American journal of medical genetics. Part A 164A(11): 2701-6, Nov 2014.

Krock Bryan L, Perkins Brian D: The Par-PrkC polarity complex is required for cilia growth in zebrafish photoreceptors. PloS One 9(8): e104661, Aug 21 2014.

Shay Jessica E S, Imtiyaz Hongxia Z, Sivanand Sharanya, Durham Amy C, Skuli Nicolas, Hsu Sarah, Mucaj Vera, Eisinger-Mathason T S Karin, Krock Bryan L, Giannoukos Dionysios N, Simon M Celeste: Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer. Carcinogenesis 35(5): 1067-77, May 2014.

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Last updated: 08/18/2017
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