Bryan L Krock, PhD

faculty photo
Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Boulevard, RM 710B ARC Bldg.
Philadelphia, PA 19104
Office: 267-426-7588
Fax: 215-590-2156
Education:
BS (Biology)
Pennsylvania State University, 2003.
PhD (Biology)
Texas A&M University, 2009.
Permanent link
 
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Selected Publications

Margraf RL, Durtschi J, Krock B, Newcomb TM, Bonkowsky JL, Voelkerding KV, Bayrak-Toydemir P, Lutz RE, Swoboda KJ.: Novel PLP1 Mutations Identified With Next-Generation Sequencing Expand the Spectrum of PLP1-Associated Leukodystrophy Clinical Phenotypes. Child Neurol Open 23(5), July 2018.

Smol T, Petit F, Piton A, Keren B, Sanlaville D, Afenjar A, Baker S, Bedoukian EC, Bhoj EJ, Bonneau D, Boudry-Labis E, Bouquillon S, Boute-Benejean O, Caumes R, Chatron N, Colson C, Coubes C, Coutton C, Devillard F, Dieux-Coeslier A, Doco-Fenzy M, Ewans LJ, Faivre L, Fassi E, Field M, Fournier C, Francannet C, Genevieve D, Giurgea I, Goldenberg A, Green AK, Guerrot AM, Heron D, Isidor B, Keena BA, Krock BL, Kuentz P, Lapi E, Le Meur N, Lesca G, Li D, Marey I, Mignot C, Nava C, Nesbitt A, Nicolas G, Roche-Lestienne C, Roscioli T, Satre V, Santani A, Stefanova M, Steinwall Larsen S, Saugier-Veber P, Picker-Minh S, Thuillier C, Verloes A, Vieville G, Wenzel M, Willems M, Whalen S, Zarate YA, Ziegler A, Manouvrier-Hanu S, Kalscheuer VM, Gerard B, Ghoumid J.: MED13L-Related Intellectual Disability: Involvement of Missense Variants and Delineation of the Phenotype. Neurogenetics 19(2): 93-103, May 2018.

Olson Heather E, Jean-Marçais Nolwenn, Yang Edward, Heron Delphine, Tatton-Brown Katrina, van der Zwaag Paul A, Bijlsma Emilia K, Krock Bryan L, Backer E, Kamsteeg Erik-Jan, Sinnema Margje, Reijnders Margot R F, Bearden David, Begtrup Amber, Telegrafi Aida, Lunsing Roelineke J, Burglen Lydie, Lesca Gaetan, Cho Megan T, Smith Lacey A, Sheidley Beth R, Moufawad El Achkar Christelle, Pearl Phillip L, Poduri Annapurna, Skraban Cara M, Tarpinian Jennifer, Nesbitt Addie I, Fransen van de Putte Dietje E, Ruivenkamp Claudia A L, Rump Patrick, Chatron Nicolas, Sabatier Isabelle, De Bellescize Julitta, Guibaud Laurent, Sweetser David A, Waxler Jessica L, Wierenga Klaas J, Donadieu Jean, Narayanan Vinodh, Ramsey Keri M, Nava Caroline, Rivière Jean-Baptiste, Vitobello Antonio, Tran Mau-Them Frédéric, Philippe Christophe, Bruel Ange-Line, Duffourd Yannis, Thomas Laurel, Lelieveld Stefan H, Schuurs-Hoeijmakers Janneke, Brunner Han G, Keren Boris, Thevenon Julien, Faivre Laurence, Thomas Gary, Thauvin-Robinet Christel: A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis. American journal of human genetics 102(5): 995-1007, May 2018.

Vajravelu Mary Ellen, Chai Jinghua, Krock Bryan, Baker Samuel, Langdon David, Alter Craig, De León Diva D: Congenital Hyperinsulinism and Hypopituitarism Attributable to a Mutation in FOXA2. The Journal of clinical endocrinology and metabolism 103(3): 1042-1047, March 2018.

Straub J, Konrad EDH, Grüner J, Toutain A, Bok LA, Cho MT, Crawford HP, Dubbs H, Douglas G, Jobling R, Johnson D, Krock B, Mikati MA, Nesbitt A, Nicolai J, Phillips M, Poduri A, Ortiz-Gonzalez XR, Powis Z, Santani A, Smith L, Stegmann APA, Stumpel C, Vreeburg M; Deciphering Developmental Disorders Study, Fliedner A, Gregor A, Sticht H, Zweier C.: Missense Variants In RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila. Am J Hum Genet 102(1): 44-57, Jan 2018.

Carolien G. F. de Kovel, PhD1,2; Steffen Syrbe, MD, PhD3; Eva H. Brilstra, MD, PhD1; Nienke Verbeek, MD, PhD1; Bronwyn Kerr, PhD4,5,6; Holly Dubbs, MD7; Allan Bayat, MD, PhD8; Sonal Desai, MGC, CGC9; Sakkubai Naidu, MD10,11; Siddharth Srivastava, MD12; Hande Cagaylan, MD13; Uluc Yis, MD, PhD14; Carol Saunders, PhD15,16,17; Martin Rook, PhD18; Susanna Plugge, MSc19; Hiltrud Muhle, MD20; Zaid Afawi, MD, PhD21; Karl-Martin Klein, MD, PhD22; Vijayakumar Jayaraman, MSc23; Ramakrishnan Rajagopalan, PhD23; Ethan Goldberg, MD, PhD7; Eric Marsh, MD, PhD7; Sudha Kessler, MD, MSCE7; Christina Bergqvist, MD7; Laura K. Conlin, PhD23; Bryan L. Krock, PhD23; Isabelle Thiffault, PhD15,16; Manuela Pendziwiat, MSc20; Ingo Helbig, MD7,24; Tilman Polster, MD, PhD25; Ingo Borggraefe, MD, PhD26; Johannes R. Lemke, MD, PhD27; Marie-José van den Boogaardt, MD, PhD1; Rikke S. Møller, MSc, PhD8,28; Bobby P. C. Koeleman, PhD1: Neurodevelopment Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes. JAMA Neurology August 2017.

Gade TPF, Tucker E, Nakazawa MS, Hunt SJ, Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, Furth EE, Winkler JD, Amaravadi RK, Simon MC: Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Radiology 283(3): 702-710, March 2017.

Abou Tayoun Ahmad N, Krock Bryan, Spinner Nancy B: Sequencing-based diagnostics for pediatric genetic diseases: progress and potential. Expert Rev Mol Diagn 17: 1-13, Aug 2016.

Mundy SA, Krock BL, Mao R, Shen JJ: BRAT1-related disease-identification of a patient without early lethality. Am J Med Genet A 170(3): 699-702, Mar 2016.

Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. : Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration Acta Neuropathol 130(3): 363-72, Sep 2015.

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Last updated: 11/15/2018
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