Jeffrey Campbell Thompson, MD, MTR

faculty photo
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Department: Medicine

Contact information
221 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Office: 215-898-3168
BS (Biomedical Sciences Summa Cum Laude)
Auburn University, 2006.
MD (Medicine)
University of Alabama at Birmingham, 2010.
University of Pennsylvania, 2017.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

J.C Thompson*, E.L. Carpenter*, B.A. Silva, J. Rosenstein, A.L. Chien, K.J. Quin, C.R. Espenschied, A. Mak, L.A. Kiedrowski, M. Lefterova, R.J. Nagy, S.S. Yee, T. Black, A.P. Singh, C.A. Ciunci, J.M. Bauml, R.B. Cohen, C.J. Langer, C. Aggarwal: Serial monitoring of circulating tumor DNA by next generation gene sequencing as a biomarker of response and survival in patients with advanced NSCLC receiving pembrolizumab-based therapy. JCO Precision Oncology 2021

. Yousefi, M. LaRiviere, E. Cohen, T. Buckingham, S. Yee, T. Black, A.Chien, P. Noel, W. Hwang, S.I. Katz, C. Aggarwal, J.C. Thompson, E.L. Carpenter, D: Non-invasive radiogenomic phenotypes of non-small cell lung cancer predict response to EGFR inhibitors: Preliminary study combining radiomics with liquid biopsy data. Scientific Reports (In Press) 2021.

C. Aggarwal, J.C Thompson, A. Chien, K. Quin, W. Hwang, T. Black, S.S. Yee, T. Christensen, M. LaRiviere, B. Silva, K. Banks, R. Nagy, E. Helman, A. Berman, C.A. Ciunci, A. Singh, J. Wasser, J.M. Bauml, C.J. Langer, R. B. Cohen, E.L. Carpenter: Baseline plasma tumor mutation burden predicts response to pembrolizumab-based therapy in patients with metastatic non-small cell lung cancer. Clinical Cancer Research 2020.

J.C. Thompson, C. Davis, C. Deshpande, W. Hwang, S. Jeffries, A. Huang, T.C. Mitchell, C.J. Langer, S.M. Albelda: A gene signature of antigen processing and presentation machinery (APM) predicts response to checkpoint blockade in Non-Small Cell Lung Cancer (NSCLC) and melanoma. Journal for ImmunoTherapy of Cancer 2020.

C. Aggarwal*, J.C Thompson*, T. Black, S. Katz, R. Fan, S.S Yee, A. Chien, T.L. Evans, J. Bauml, E. Alley, C. Ciunci, A. Berman, R. Cohen, D. Lieberman, K. Majmundar, S.L Savitch, J.D. Morrissette, W. Hwang, K. Elenitoba-Johnson, C.J. Langer, E.L. Carpenter.: Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non–small cell lung cancer. JAMA Oncology 5(2): 173-180, Feb 2019.

J. Kargl, X. Zhu, H. Zhang, G. Yang, T. Riesen, M. Shipley, D. Maeda, J. Zebala, J. Mckay-Fleisch, G. Meredith, A. Mashadi-Hossein, C. Baik, R.H. Pierce, M.W. Redman, J.C. Thompson, S.M. Albelda, H. Bolouri, A.M. Houghton: Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC. JCI Insight 2019.

Klampatsa S. O’Brien, J. C. Thompson, S. A.S. Rao, J.E. Standalick, M. Martinez, M. Liousia, E. Cantu, K. Cengel, E. Moon E, S. Singhal, E.B. Eruslanov, S.M Albelda: Phenotypic and Functional Analysis of Malignant Mesothelioma Tumor-Infiltrating Lymphocytes (TILs). Oncoimmunology Jul 2019.

C. Aggarwal, C. Davis, R. Mick, J.C. Thompson, S. Ahmed, S. Jeffries, S. Bagley, P. Gabriel, T.L. Evans, J. Bauml, C. Ciunci, E. Alley, J.D. Morrissette, R. Cohen, E.L. Carpenter, C. Langer: Influence of TP53 Mutation on Survival and Transformation to Small Cell Lung Cancer in Patients with Advanced EGFR-Mutant Non-Small Cell Lung Cancer JCO Precision Oncology published on line , Nov 2018.

S.M Obrien, A. Klampatsa, J.C.Thompson, M. Martinez, W. Hwang, A. Rao, J. Standalick, S. Kim, E. Cantu, L. Litzky, S. Singhal, E. Eruslanov, E.K. Moon, S.M. Albelda: Function of Human Tumor Infiltrating Lymphocytes in Early Stage Non-Small Cell Lung Cancer. Cancer Immunology Research May 2019.

J.C. Thompson, W. Hwang, C. Davis, C. Deshpande, S. Jeffries, Y. Rajpurohit, V. Krishna, D. Smirnov, R. Verona, M.V. Lorenzi, C.J. Langer, S.M. Albelda: Gene Signatures of Tumor Inflammation and Epithelial-to-Mesenchymal Transition (EMT) Predict Responses to Immune Checkpoint Blockade in Lung Cancer with High Accuracy. Lung Cancer Oct 2019.

J.C. Thompson, R. Fan, T. Black, G.H. Yu, S.L. Savitch, A. Chien, S. Yee, M. Sen, W. Hwang, S.I. Katz, M. Feldman, A. Vachani, E.L. Carpenter. : Measurement and Immunophenotyping of pleural EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 127: 25-33, Jan 2019.

M. Marmarelis, E. Bange, W. Hwang, Y. Yang, J.C. Thompson, J. Rosenbaum, J. Bauml, C.Ciunci, E. Alley, R. Cohen, C. Langer, E. Carpenter, C. Aggarwal: Impact of KRAS and TP53 co-mutations on outcomes following first-line systemic among patient with STK11 mutated advanced NSCLC. JCO Precision Oncology May 2019.

M. Marmarelis, J.C. Thompson, C. Aggarwal, T.L. Evans, E. Carpenter. R.B. Cohen, C.J. Langer, J. Bauml.: Emerging uses of circulating tumor DNA in advanced stage non-small cell lung cancer. Ann Transl Med. 5(18): 380, Sep 2017.

S. Katz, M. Hammer, S.J. Bagley, C. Aggarwal, J. Bauml, J.C. Thompson, A.C. Nachiappan, C.B. Simone, C. Langer. : Radiologic pseudoprogression during anti-PD1 therapy for advanced non-small lung cancer. J Thorac Oncol. 13(7): 978-986, Jul 2018.

J. C. Thompson, S.S Yee, A.B. Troxel, S.L. Savitch , R. Fan , D. Balli , D.B. Lieberman, J.D Morrissette, T.L Evans, J. Bauml ,C. Aggarwal, J.A Kosteva, E. Alley, C. Ciunci, R.B. Cohen, S. Bagley, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, C. Langer, A. Vachani, E. Carpenter: Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 22(23): 5772-5782, Dec 2016.

S.J. Bagley, S. Kothari, C. Aggarwal, J. Bauml, E. Alley, T.L Evans, J.A. Kosteva, C. Ciunci, J.C. Thompson, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, B. Sandy, F. Mutale, G. DiLullo, R.B. Cohen, A. Vachani, C. Langer. : Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab treated patients with advanced non-small cell lung cancer. Lung Cancer 106: 1-7, Apr 2017.

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Last updated: 04/16/2021
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