Saba Sheikh, MBBS, MSCE

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
3501 Civic Center Boulevard
11th Floor Colket Building
Division of Pulmonary Medicine
Philadelphia, PA 19104
Office: 215-590-3749
Fax: 215-590-3500
Education:
MBBS
The Aga Khan University, Karachi, Pakistan, 2005.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2014.
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Description of Clinical Expertise

Dr. Sheikh is a pediatric pulmonologist with expertise in CF, CF metabolic syndrome and lung transplant.

Description of Research Expertise

Dr. Sheikh has expertise in clinical studies of Cystic Fibrosis (CF) and Cystic Fibrosis Related Diabetes (CFRD).

Selected Publications

Harris C, Kilberg MJ, Sheikh, S, Stefanovski, D, Cuchel, M, Kubrak, C, Hadjiliadis, D, Rubenstein, RC, Rickels, MR; Kelly, A: Hypoglycemia Following OGTT Is More Frequent and Pronounced In CF Compared With Controls. Journal of the Endocrine Society 2020.

Saba Sheikh, Andrea Kelly, Darko Stefanovski, Amy J. Peleckis, Sarah C. Nyirjesy, Jack N. Eiel, Christina Kubrak, Aniket Sidhaye, A. Russell Localio, Diva D. De Leon, Denis Hadjiliadis, Ronald C. Rubenstein, and Michael R. Rickels: Effects of DPP4 inhibition on the enteroinsular axis in glucose intolerant adults with pancreatic insufficient cystic fibrosis. Diabetes Care 2020.

Sheikh S, Localio AR, Kelly A, Rubenstein RC: Abnormal glucose tolerance and the 50-gram glucose challenge test in Cystic fibrosis. Journal of Cystic Fibrosis 2020.

Zysman-Colman,Z., Kilberg, MJ., Harrison, VS., Chesi, A., Grant, SFA., Mitchell, J, Sheikh, S., Hadjiliadis, D., Rickels, MR.; Rubenstein, RC., Kelly, A. : Genetic Potential and Height Velocity during Childhood and Adolescence do not Fully Account for Shorter Stature in Cystic Fibrosis. Pediatr Res. 2020.

Kilberg MJ, Sheikh S, Stefanovski D, Kubrak C, De Leon DD, Hadjiliadis D, Rubenstein RC, Rickels MR, Kelly A: Dysregulated insulin in pancreatic insufficient cystic fibrosis with post-prandial hypoglycemia. Journal of Cystic Fibrosis Page: doi: 10.1016, Aug 2019 Notes: epub ahead of print.

Kelly A, De Leon DD, Sheikh S, Camburn D, Kubrak C, Peleckis AJ, Stefanovski D, Hadjiliadis D, Rickels MR, Rubenstein RC.: Islet Hormone and Incretin Secretion in Cystic Fibrosis after Four Months of Ivacaftor Therapy. Am J Respir Crit Care Med 199(3): 342-351, 2019.

Sheikh, S, Rubenstein, RC, Kelly A, Rickel, MR: Insulin secretion worsens over time in pancreatic insufficient cystic fibrosis. The North American Cystic Fibrosis Conference, Nashville 2019.

Sarah C. Nyirjesy, Saba Sheikh, Denis Hadjiliadis, Diva D. De Leon, Amy J. Peleckis, Jack N. Eiel, Christina Kubrak, Darko Stefanovski, Ronald C. Rubenstein, Michael R. Rickels, and Andrea Kelly: β-cell Secretory Defects are Present in Pancreatic Insufficient Cystic Fibrosis with 1-hour OGTT Glucose ≧155 mg/dL. Pediatric Diabetes 19(7): 1173-1182, Nov 2018.

Sheikh S., Gudipaty L., De Leon D.D., Hadjiliadis D., Kubrak C., Rosenfeld N.K., Nyirjesy S., Pelekis A., Malik S., Stefanovski D., Cuchel M., Rubenstein R.C., Kelly A., and Rickels M.R.: Reduced β-Cell Secretory Capacity in Pancreatic Insufficient, but Not Pancreatic Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance. Diabetes 66(2): 134-144, Jan 2018.

S Sheikh, S.C. Nyirjesy, D Hadjiliadis, D De Leon, A.J. Peleckis, J.N. Eiel, C Kubrak, D Stefanovski, R.C. Rubenstein, M.R. Rickels, and A Kelly: Hyperglucagonemia and incretin defects do not worsen glucose tolerance in pancreatic insufficient cystic fibrosis with glucose intolerance. North American Cystic Fibrosis Conference, Indianapolis, IN 2017 Notes: Podium Presentation.

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Last updated: 12/11/2020
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