Edimara Da Silva Reis, Ph.D.

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Research Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
University of Pennsylvania
422 Curie Blvd.
401 Stellar Chance Labs
Philadelphia, PA 19104
Office: 215-746-5760
M.Sc (Immunology)
University of Sao Paulo, 2004.
PhD (Immunology)
University of Sao Paulo, 2008.
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Selected Publications

Xavier Sandhya, Sahu Ranjit K, Landes Susan G, Yu Jing, Taylor Ronald P, Ayyadevara Srinivas, Megyesi Judit, Stallcup William B, Duffield Jeremy S, Reis Edimara S, Lambris John D, Portilla Didier: Pericyte and immune cells contribute to complement activation in tubulointerstitial fibrosis. American journal of physiology. Renal physiology Jan 2017 Notes: Epub. https://doi.org/10.1152/ajprenal.00604.2016.

Primikyri Alexandra, Papanastasiou Malvina, Sarigiannis Yiannis, Koutsogiannaki Sophia, Reis Edimara S, Tuplano Joel V, Resuello Ranillo R G, Nilsson Bo, Ricklin Daniel, Lambris John D: Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 1041-1042: 19-26, Dec 2016.

Ricklin Daniel, Reis Edimara S, Mastellos Dimitrios C, Gros Piet, Lambris John D: Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense. Immunological reviews 274(1): 33-58, Nov 2016.

Lindorfer Margaret A, Cook Erika M, Reis Edimara S, Ricklin Daniel, Risitano Antonio M, Lambris John D, Taylor Ronald P: Compstatin Cp40 blocks hematin-mediated deposition of C3b fragments on erythrocytes: Implications for treatment of malarial anemia. Clinical immunology 171: 32-35, Oct 2016.

Mastellos Dimitrios C, Reis Edimara S, Yancopoulou Despina, Hajishengallis George, Ricklin Daniel, Lambris John D: From orphan drugs to adopted therapies: Advancing C3-targeted intervention to the clinical stage. Immunobiology 221(10): 1046-57, Oct 2016.

Doerner Stephanie K, Reis Edimara S, Leung Elaine S, Ko Justine S, Heaney Jason D, Berger Nathan A, Lambris John D, Nadeau Joseph H: High-Fat Diet-Induced Complement Activation Mediates Intestinal Inflammation and Neoplasia, Independent of Obesity. Molecular cancer research 14(10): 953-965, Oct 2016.

Min Jun S, DeAngelis Robert A, Reis Edimara S, Gupta Shakti, Maurya Mano R, Evans Charles, Das Arun, Burant Charles, Lambris John D, Subramaniam Shankar: Systems Analysis of the Complement-Induced Priming Phase of Liver Regeneration. Journal of immunology 197(6): 2500-8, Sep 2016.

Ricklin Daniel, Reis Edimara S, Lambris John D: Complement in disease: a defence system turning offensive. Nature reviews. Nephrology 12(7): 383-401, Jul 2016.

Reis Edimara S, Mastellos Dimitrios C, Yancopoulou Despina, Risitano Antonio M, Ricklin Daniel, Lambris John D: Applying complement therapeutics to rare diseases. Clinical immunology 161(2): 225-40, Dec 2015.

Sfyroera Georgia, Ricklin Daniel, Reis Edimara S, Chen Hui, Wu Emilia L, Kaznessis Yiannis N, Ekdahl Kristina N, Nilsson Bo, Lambris John D: Rare loss-of-function mutation in complement component C3 provides insight into molecular and pathophysiological determinants of complement activity. Journal of immunology 194(7): 3305-16, Apr 2015.

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Last updated: 03/06/2017
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