Thomas B Karasic, MD

faculty photo
Assistant Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Physician Leader, Developmental Therapeutics, University of Pennsylvania
Department: Medicine

Contact information
3400 Civic Center Blvd
PCAM South Tower 10-102
Philadelphia, PA 19104
Office: 215-615-1594
Fax: 215-662-2432
Education:
BA (Chemistry and Biology)
Cornell University, 2008.
MD (Medicine)
Columbia University College of Physicians and Surgeons, 2012.
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Selected Publications

Mamta Gupta, PhD, Hoon Choi, PhD, Emma E Furth, MD, Miguel Joaquim, MS, Stephen Pickup, PhD, Cynthia Clendenin, DVM, Margo Orlen, BS, Thomas Karasic, MD, Hee Kwon Song, PhD, Yong Fan, PhD, Peter O’Dwyer, MD, Robert H. Vonderheide, MD, DPhil, Mark Rosen, MD, PhD, Ben Z. Stanger, MD, PhD, Rong Zhou, PhD: Quantitative MRI Metrics Capture Pancreatic Cancer and Stroma Responses to Novel KRAS Inhibitor. World Molecular Imaging Congress 2023 Sep 2023.

Van K. Morris, Katherine A Guthrie, Scott Kopetz, Rimini Breakstone, Thomas Benjamin Karasic, Zishuo Ian Hu, Shay Bellasea, Marwan Fakih, Sepideh Gholami, Philip Jordan Gold, and Philip Agop Philip: SWOG S2107 - Randomized Phase II Trial of Encorafenib and Cetuximab with or Without Nivolumab for Patients with Previously Treated, Microsatellite Stable, BRAFV600E Metastatic and/or Unresectable Colorectal Cancer. ASCO Annual Meeting 2023 Jun 2023.

William Joseph Chapin, Parul Agarwal, Lisa DiCicco, Rayleigh Palmer, Nadia Cenou, Alexander Chan Chi Huang, and Thomas Benjamin Karasic: Phase II trial of XmAb20717 (vudalimab) in patients with advanced biliary tract cancers. ASCO Annual Meeting 2023 June 2023.

Susanna Varkey Ulahannan, John D. Powderly, Melissa Lynne Johnson, John C. Krauss, Manish Sharma, Diwakar Davar, Thomas Benjamin Karasic, Stephanie Gaillard, Yonchu Jenkins, Robert J. Stagg, Darrin Bomba, Nathan Standifer, Steven Smith, Peppi Prasit, Thomas Walter Dubensky, Sam H. Whiting, and Kyriakos P. Papadopoulos: A phase 1 study of TPST-1495 as a single agent and in combination with pembrolizumab in patients with advanced solid tumors. ASCO Annual Meeting 2023 June 2023.

Jayesh Desai; Sae-Won Han; Jong-Seok Lee; Einat Shacham-Shmueli; Erminia Massarelli; Andrés Cervantes; Elena Garralda; Alejandro Falcon; Wilson H. Miller; Eelke Gort; Thomas Karasic; Salvatore Siena; Rafal Stec; Laura Medina; Luis Paz-Arez; Angelo Delmonte; Adrian Sacher; Hans Prenen; Martin Forster; Tae Won Kim; Matthew G. Krebs; Rasha Cosman; Yoonha Choi; Sandhya Mandlekar; Mark T. Lin; Kenneth K. Yau; Julie Chang; Stephanie Royer-Joo; Neekesh V. Dharia; Jennifer L. Schutzman; Manish Patel: Phase Ib study of GDC-6036 in combination with cetuximab in patients with colorectal cancer (CRC) with KRAS G12C mutation. AACR Annual Meeting 2023 Apr 2023.

Samuele Cannas; Jacob E. Till; Kristine Kim; Michael J. LaRiviere; Charles M. Vollmer; Jennifer R. Eads; Thomas B. Karasic; Peter J. O'Dwyer; Charles J. Schneider; Ursina R. Teitelbaum; Kim A. Reiss Binder; Mark H. O'Hara; Douglas T. Ross; Kim McGregor; Kirsten Bornemann-Kolatzki; Ekkehard Schütz; Julia Beck; Erica L. Carpenter: Liquid biopsy signature combining copy number instability and mutant KRAS detection is associated with survival for patients with metastatic pancreatic cancer. AACR Annual Meeting 2023 Apr 2023.

Karasic TB, Eads JR, Goyal L: Precision Medicine and Immunotherapy Have Arrived for Cholangiocarcinoma: An Overview of Recent Approvals and Ongoing Clinical Trials. JCO Precision Oncology. JCO Precision Oncology March 2023.

Brown TJ, Mamtani R, Gimotty PA, Karasic TB, Yang YX: Outcomes of hepatocellular carcinoma by etiology with first-line atezolizumab and bevacizumab: a real-world analysis. J Cancer Res Clin Oncol Jan 2023.

Timothy J Brown, Ronac Mamtani, Phyllis A. Gimotty, Thomas Benjamin Karasic, and Yu-Xiao Yang: Impact of etiology of hepatocellular carcinoma on treatment outcomes in a real-world database. GI ASCO Meeting 2023 Jan 2023.

Timothy J Brown, Andy J Minn, Erica L. Carpenter, Edgar Ben-Josef, and Thomas Benjamin Karasic: A phase I clinical trial of stereotactic body radiotherapy with atezolizumab and bevacizumab in advanced hepatocellular carcinoma. GI ASCO Meeting 2023 Jan 2023.

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Last updated: 11/03/2023
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