faculty photo

Vera Moiseenkova-Bell, PhD

Associate Professor of Pharmacology
Department: Pharmacology

Contact information
Department of Systems Pharmacology and Translational Therapeutics
University of Pennsylvania, Perelman School of Medicine
10-124 Smilow Center for Translational Research
3400 Civic Center Boulevard, Building 421
Philadelphia, PA 19104-5158
Office: 215 898-1154
Education:
MS (Laser Biophysics)
M.V. Lomonosov Moscow State University, 1999.
PhD (Cellular Physiology & Molecular Biophysics)
The University of Texas Medical Branch, 2004.
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Selected Publications

2. Hughes T.E.T., Pumroy R.A., Yazici A.T., Kasimova M.A., Fluck E.C., Huynh K.W., Samanta A., Molugu S., Zhou Z.H., Carnevale V., Rohacs T., Moiseenkova-Bell V.Y. : Structural insights on TRPV5 gating by endogenous modulators. Nature Communications 9 (1):4198, October 2018.

Samanta A., Hughes T., Moiseenkova-Bell V.Y: Transient Receptor Potential (TRP) Channels. Subcell Biochemistry Membrane-bound Macromolecular Protein Complexes: Structure and Function, Springer 87: 141-165, February 2018.

Basak S., Gicheru Y., Samanta A., Molugu S.K.,, Huang W., de la Fuente M., Hughes T., Taylor D.J., Nieman M.T., Moiseenkova-Bell V.Y., Chakrapani S. : Cryo-EM structure of 5-HT3A receptor in its resting conformation. Nature Communications 514: doi:10.1038/s41467-018-02997-4. February 2018.

Hughes T.E.T., Lodowski D.T., Huynh K.W., del Rosario J., Yazici A., Kapoor A., Basak S., Samanta A., Chakrapani S., Zhou Z.H., Filizola M., Rohacs T., Han S., Moiseenkova-Bell V.Y. : Structural basis of the TRPV5 channel inhibition revealed by cryo-EM. Nature Structural & Molecular Biology. Nature Structural & Molecular Biology, 1: 53-60, January 2018.

Samanta A., Hughes T.E.T., Moiseenkova-Bell V.Y. : Cryo electron microscopy of TRP channels. Methods in Molecular Biology, Springer 2018 Notes: in press.

Samanta A., Kiselar J., Han S., Moiseenkova-Bell V.Y.: Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition. The Journal of General Physiology 2018 Notes: in press.

Arne J.M., Widjaja-Adhi M.A., Hughes T., Huynh K.W., Silvaroli J.A., Chelstowska S., Moiseenkova-Bell V.Y., Golczak M.: Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2 (AWAT2). Journal of Lipid Research 58(4): 719-730, 2017 Notes: doi: 10.1194/jlr.M073692, Epub Jan 17 2017.

Huynh K.W., Cohen M.R., Jiang J., Samanta A., Lodowski D.T., Zhou Z.H., Moiseenkova-Bell V.Y.: Structure of the full-length TRPV2 channel by cryo-EM. Nature Communications 7: 11130, 2016 Notes: doi: 10.1038/ncomms11130.

Cohen M.R., Johnson W.M., Pilat J.M., Kiselar J., DeFrancesco-Lisowitz A., Zigmond R.E., Moiseenkova-Bell V.Y.: NGF regulates TRPV2 via ERK signaling to enhance neurite outgrowth in developing neurons. Molecular and Cellular Biology 35(24): 4238-4252, 2015 Notes: Epub Sep 28 2015.

Huynh K.W., Cohen M.R., Moiseenkova-Bell V.Y.: Application of amphipols for structure-functional analysis of TRP channels. Journal of Membrane Biology 247(9-10): 843-851, 2014 Notes: Epub June 4 2014.

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Last updated: 01/16/2019
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