Selected Publications

Goodsaid, F., Frueh, F., Burczynski, ME.: Personalized Medicine. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Hock, F. and Gralinski, M. (eds.). Springer, 2019.

Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, Tan LJ, Bur-czynski ME, Zeskind B, Laifenfeld D, Pouladi M, Geva M, Grossman I, Hayden MR: Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expres-sion and activates neuroprotective pathways in the YAC128 HD mouse. Mol Neurodegener 13(1):25, May 2018 Notes: doi: 10.1186/s13024-018-0259-3.

Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, Tan LJ, Burczynski ME, Zeskind B, Laifenfeld D, Pouladi M, Geva M, Grossman I, Hayden MR.: Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse. Mol Neurodegener 13(1), May 2018.

Laterza OF, Plump A, Ming JE, Richards S, Burczynski ME, Wagner JW, Patterson SD: Biomarkers in the Pharmaceutical Industry. Clin Chem Page: doi: 10.1373/clinchem.2014.225284. Epub Apr 2015.

Harris P, Sridhar S, Peng R, Phillips J E, Cohn R G, Burns L, Woods J, Ramanujam M, Loubeau M, Tyagi G, Allard J, Burczynski M, Ravindran P, Cheng D, Bitter H, Fine J S, Bauer C M T, Stevenson C S: Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD. Mucosal immunology Sep 2012.

Pant Saumya, Hilton Holly, Burczynski Michael E: The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities. Biochemical pharmacology 83(11): 1484-94, Jun 2012.

Allantaz Florence, Cheng Donavan T, Bergauer Tobias, Ravindran Palanikumar, Rossier Michel F, Ebeling Martin, Badi Laura, Reis Bernhard, Bitter Hans, D'Asaro Matilde, Chiappe Alberto, Sridhar Sriram, Pacheco Gonzalo Duran, Burczynski Michael E, Hochstrasser Denis, Vonderscher Jacky, Matthes Thomas: Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression. PloS one 7(1): e29979, 2012.

Weidlich S, Walsh K, Crowther D, Burczynski M E, Feuerstein G, Carey F A, Steele R J C, Wolf C R, Miele G, Smith G: Pyrosequencing-based methods reveal marked inter-individual differences in oncogene mutation burden in human colorectal tumours. British journal of cancer 105(2): 246-54, Jul 2011.

Coughlin Christina M, Johnston Daniel S, Strahs Andrew, Burczynski Michael E, Bacus Sarah, Hill Jason, Feingold Jay M, Zacharchuk Charles, Berkenblit Anna: Approaches and limitations of phosphatidylinositol-3-kinase pathway activation status as a predictive biomarker in the clinical development of targeted therapy. Breast cancer research and treatment 124(1): 1-11, Nov 2010.

Goodsaid Federico M, Amur Shashi, Aubrecht Jiri, Burczynski Michael E, Carl Kevin, Catalano Jennifer, Charlab Rosane, Close Sandra, Cornu-Artis Catherine, Essioux Laurent, Fornace Albert J, Hinman Lois, Hong Huixiao, Hunt Ian, Jacobson-Kram David, Jawaid Ansar, Laurie David, Lesko Lawrence, Li Heng-Hong, Lindpaintner Klaus, Mayne James, Morrow Peter, Papaluca-Amati Marisa, Robison Timothy W, Roth John, Schuppe-Koistinen Ina, Shi Leming, Spleiss Olivia, Tong Weida, Truter Sharada L, Vonderscher Jacky, Westelinck Agnes, Zhang Li, Zineh Issam: Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact. Nature reviews. Drug discovery 9(6): 435-45, Jun 2010.