Department of Anesthesiology and Critical Care

Home About Us Faculty Patient Care Education Research
faculty photo

W. Andrew Kofke, MD MBA FCCM FNCS

Emeritus Professor CE of Anesthesiology and Critical Care
COAP Committee, Hospital of the University of Pennsylvania
Chair's Advisory Committee, Hospital of the University of Pennsylvania, Department of Anesthesia
Director Neuroanesthesia, Section Chief/ORL/Uro, University of Pennsylvania School of Medicine, Philadelphia, PA
Main OR Coordinator, Hospital of the University of Pennsylvania, Philadelphia, PA
Professor, Department of Neurosurgery, Hospital of the University of Pennsylvania
Staff Anesthesiologist, Hospital of the University of Pennsylvania
Substance Abuse Committee, Hospital of the University of Pennsylvania, Department of Anesthesia
Chair, Pain Director Search Committee, Hospital of the University of Pennsylvania, Department of Anesthesia
Chair, Recruiting Committee, Hospital of the University of Pennsylvania, Department of Anesthesia
Off Hours Task Force, Department of Anesthesia, Hospital of the University of Pennsylvania
Staff Anesthesiologist (for VISICU), Pennsylvania Hospital
Co-Director, Neuro ICU, Hospital of the University of Pennsylvania
Director, Measey Medical Simulation Center, University of Pennsylvania, School of Medicine
New Clinical Business Committee, University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
HUP - 7 Dulles
34th and Spruce Street
Philadelphia, PA 19104
Office: (215) 349-8993
Fax: (215) 615-3898
BS (Chemistry)
Bucknell University, 1974.
University of Pittsburgh School of Medicine, 1978.
MBA (Health Sciences Emphasis)
West Virginia University, 1999.
Post-Graduate Training
Internship, Mercy Hospital, Pittsburgh, PA, 1978-1979.
Resident, Anesthesiology, Massachusetts General Hospital, Boston, 1979-1981.
Fellowship, Critical Care Medicine, Massachusetts General Hospital, Boston, 1982-1983.
Sabbatical, Graduate Courses: Neuroscience I, Neuroscience II, Molecular Neurobiology , Pittsburgh, PA, 1991-1992.
Emergency Medical Technician, Pennsylvania, 1969.
American Board of Anesthesiology, 1983.
Instructor, Advanced Trauma Life Support, 1985.
American Board of Anesthesiology, subspecialty certification in Critical Care Medicine , 1986.
Basic and Advanced Cardiac Life Support Certified, 1991.
American Board of Anesthesiology, Continued Demonstration of Qualifications (recertification), 1993.
Instructor, Fundamentals of Critical Care Support, 1999.
Patient Safety Leadership Academy graduate, Wharton School, University of Pennsylvania, 2003.
Center for Medical Simulation Instructors' Course, Harvard, 2005.
Neurocritical Care subspecialty certification, United Council of Neurologic Subspecialties, 2007.
Recertification Neurocriticalcare (UNSC), 2020.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

Physiology, rodents, anesthetic neurotoxicity

Description of Clinical Expertise

Neuroanesthesia, Neuro ICU

Selected Publications

DeYoung, T.P., Li, J.C., Tang, X., Ward, C.G., Dworkin, B.R., Eckenhoff, M.F., Kofke, W.A.: Absence of Neuropathology With Prolonged Isoflurane Sedation in Healthy Adult Rats. Journal of Neurosurgical Anesthesiology October 2017.

Baker WB, Parthasarathy AB,Gannon KP, Kavuri VC, Busch DR, Abramson K, He L, Mesquita RC, Mullen MT, Detre JA, Greenberg JH, Licht DJ, Balu R, Kofke WA, Yodh AG: Noninvasive optical monitoring of critical closing pressure and arteriole compliance in human subjects. J Cereb Blood Flow Metab 8(37): 2691-2705, Aug 2017.

Chitra Sivasankar, Todd Miano, Guy Kositratna, Robert Hurst, Andrew Kofke: Anesthetic Variation and Potential Impact of Anesthetics Used During Endovascular Management of Acute Ischemic Stroke. Journal of NeuroInterventional Surgery 8(11): 1101-1106, Nov 2016 Notes: Manuscript ID neurintsurg 2015-011998.

Marlon Schwarz, Giovanni Rivera, Mary Hammond, Zmira Silman, Kirk Jackson, W. Andrew Kofke: Acousto-Optic Cerebral Blood Flow Monitoring During Induction of Anesthesia in Humans. Neurocritical Care Society. Springer, 24(3): 436-441, 2016.

Kosty JA, LeRoux PD, Levine J, Park S, Kumar MA, Frangos S, Maloney-Wilensky E, Kofke WA: Comparison of Clinical and Research Practices in Measuring Cerebral Perfusion Pressure (CPP): A Literature Review and Practitioner Survey. Anes Analg 117(3): 694-8, 2013

Bohman LE, Pisapia J, Sanborn MR, Frangos S, Lin E, Callahan D, Kumar M, Park S, Kofke WA, Stiefel MF, LeRoux PD, Levine JM: Response of brain oxygen to therapy correlates with long term outcome in patients with aneurysm subarachnoid hemorrhage. Neurocritical Care 19(3): 320-328, 2013

Nelson P, Nelson JA, Chen AJ, Kofke WA: An Alternative Position for the BIS-Vista Montage in Frontal Approach Neurosurgical Cases. J Neurosurg Anesthesiol 25(2): 135-142, April 2013.

Kosty, J.A., Leroux, P.D., Levine, J., Park, S., Kumar, M.A., Frangos, S., Maloney-Wilensky, E., Kofke, W.A. : A comparison of clinical and research practices in measuring cerebral perfusion pressure: A literature review and practitioner survey Anesthesia and Analgesia 2013.

Nelson, P., Nelson, J.A., Chen, A.J., Kofke, W.A. : An alternative position for the bis-vista montage in frontal approach neurosurgical cases Journal of Neurosurgical Anesthesiology 2013.

Kosty J, Kofke WA, Maloney-Wilensky E, Frangos S, Levine JM, LeRoux PD, Zager E: Physiologic Effects of Xenon in Xenon-CT Cerebral Blood Flow Studies on Comatose Patients. Translational Stroke Research Springer-Verlag, 3(3): 375-380, September 2012

back to top
Last updated: 08/24/2021
The Trustees of the University of Pennsylvania