Department of Anesthesiology and Critical Care

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Jeff E. Mandel, MD MS

Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania
Attending Anesthesiologist, Hospital of the University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
Department of Anesthesiology & Critical Care
7 Dulles
3400 Spruce Street
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Office: 215-615-0553
Fax: 215-349-8133
BA (Biochemistry)
Rice University, 1976.
University of Texas Health Science Center at San Antonio, 1980.
MS (Engineering Sciences, Systems Science)
University of California, San Diego, 1985.
Post-Graduate Training
Intern in Anesthesia, Baylor College of Medicine, 1980-1981.
Resident in Anesthesia, Hospital of the University of Pennsylvania, 1981-1982.
Resident in Anesthesia, Ohio State University, 1982-1983.
Research Fellow, University of California at San Diego, 1983-1985.
Diplomate, American Board of Anesthesiology, 1985.
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Description of Research Expertise

Dr. Mandel has expertise in adaptive optimal control theory and pharmacokinetic modelling. He has conducted research in patient-controlled sedation.

Description of Clinical Expertise

Dr. Mandel specializes in anesthesia for otorhinolaryngologic procedures, particularly procedures of the trachea and larynx. He has special expertise in high frequency jet ventilation and total intravenous anesthesia. He has also been involved in developing new methods for sedation in GI endoscopy, interventional pulmonary procedures, and cardiac electrophysiology procedures.

Description of Other Expertise

Dr. Mandel has formal training in film and video production, and has produced video which has been presented at multiple national meetings.

Selected Publications

Mountantonakis Stavros E, Elkassabany Nabil, Kondapalli Lavanya, Marchlinski Francis E, Mandel Jeff E, Hutchinson Mathew D: Provocation of Atrial Fibrillation Triggers During Ablation: Does the Use of General Anesthesia Affect Inducibility? Journal of cardiovascular electrophysiology 26(1): 16-20, Jan 2015.

Mandel, JE: Application of pharmacokinetic and pharmacodynamic modeling to guide propofol administration for endoscopy procedures. Clinical Pharmacology for Anesthesiology. McGraw Hill, Page: 427-436, 2015.

Atkins Joshua H, Mandel Jeff E: Performance of Masimo Rainbow Acoustic Monitoring for Tracking Changing Respiratory Rates Under Laryngeal Mask Airway General Anesthesia for Surgical Procedures in the Operating Room: A Prospective Observational Study. Anesthesia and analgesia 119(6): 1307-1314, Dec 2014.

Atkins Joshua H, Mandel Jeff E, Rosanova Giulia: Safety and efficacy of drug-induced sleep endoscopy using a probability ramp propofol infusion system in patients with severe obstructive sleep apnea. Anesthesia and analgesia 119(4): 805-10, Oct 2014.

Tietäväinen A Hæggström E Mandel JE: Evaluation of postural steadiness before and after sedation: comparison of four nonlinear and three conventional measures. Physiological Measurement 35(2): 139, Feb 2014.

Mandel, Jeff E: Considerations for the use of short-acting opioids in general anesthesia. J Clin Anesthesia 26(1): S1-7, Jan 2014.

Sarraf Elie, Mandel Jeff E: Time-delay when updating infusion rates in the graseby 3400 pump results in reduced drug delivery. Anesthesia and analgesia 118(1): 145-50, Jan 2014.

Mandel, JE: High Frequency Ventilation for Respiratory Immobilization. Non-Operating Room Anesthesia: Expert Consult. Weiss, MS, and Fleisher, LA (eds.). Elsevier, Page: 117-125, 2014.

Tietäväinen, A Gates, FK Meriläinen A Mandel JE Hæggström E: Nintendo® Wii Fit based sleepiness tester detects impairment of postural steadiness due to 24 h of wakefulness. Medical Engineering & Physics 35(12): 1850-1853, Dec 2013.

Atkins Joshua H, Mandel Jeff E: Abdominal relaxation during emergence from general anesthesia with propofol and remifentanil. Journal of clinical anesthesia 25(2): 106-9, Mar 2013.

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Last updated: 03/17/2015
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