Department of Anesthesiology and Critical Care

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Max B. Kelz, MD PhD

David E. Longnecker Associate Professor of Anesthesiology and Critical Care
MSTP Program Advisor, University of Pennsylvania
Director for Research Education, Department of Anesthesiology, University of Pennsylvania, Perelman School of Medicine
Director, Dripps Research Fellowship Program, University of Pennsylvania
MSTP Program Steering Committee, University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
3620 Hamilton Walk,
John Morgan Building - Room 334
Philadelphia, PA 19104
Office: 215 573-8208
Fax: 215 349-5078
Lab: 215 898-8929
Graduate Group Affiliations
Education:
BS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
MS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
PhD (Neuroscience)
Yale University, 1999.
MD (Medicine)
Yale University, 2000.
Post-Graduate Training
Transitional Internship, University of Pennsylvania Perelman School of Medicine, 2000-2001.
Resident in Anesthesiology, University of Pennsylvania Perelman School of Medicine, 2001-2004.
Certifications
Diplomat, National Board of Medical Examiners, 2001.
Diplomat, American Board of Anesthesiology, 2005.
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Description of Research Expertise

Molecular Mechanisms of Anesthetic Action
Neurobiology of Sleep Wake Regulation
Mouse Genetics
Molecular Biology
Anesthetic pharmacology

Description of Clinical Expertise

Anesthesiology

Selected Publications

Shortal BP, Hickman LB, Mak-McCully RA, Wang W, Brennan C, Ung H, Litt B, Tarnal V, Janke E, Picton P, Blain-Moraes S, Maybrier HR, Muench MR, Lin N, Avidan MS, Mashour GA, McKinstry-Wu AR, Kelz MB, Palanca BJ, Proekt A; ReCCognition Study Group: Duration of EEG suppression does not predict recovery time or degree of cognitive impairment after general anaesthesia in human volunteers. Br J Anaesth 123(2): 206-18, Aug 2019.

Aggarwal A, Brennan C, Shortal B, Contreras D, Kelz MB, Proekt A: Coherence of Visual-Evoked Gamma Oscillations Is Disrupted by Propofol but Preserved Under Equipotent Doses of Isoflurane. Front Syst Neurosci 13: 19, May 2019.

Li D, Vlisides PE, Kelz MB, Avidan MS, Mashour GA, ReCCognition Study Group: Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers. Anesthesiology in press, 2019.

McKinstry-Wu AR, Wasilczuk AZ, Harrison BA, Bedell VA, Sridharan MJ, Breig JJ, Pack M, Kelz MB, Proekt A: Analysis of Stochastic Fluctuations in Responsiveness is a Critical Step Towards Personalized Anesthesia. eLife in press, 2019.

Ferreira AL, Correia R, Vide S, Ferreira AD, Kelz MB, Mendes JG, Nunes CS, Amorim P: Patterns of Hysteresis between Induction and Emergence of Neuroanesthesia are Present in Spinal and Intracranial Surgeries. J Neurosurg Anesthesiol Page: epub ahead of print, Oct 2018.

Palanca BJA, Maybrier HR, Mickle AM, Farber NB, Hogan RE, Trammel ER, Spencer JW, Bohnenkamp DD, Wildes TS, Ching S, Lenze E, Basner M, Kelz MB, Avidan MS.: Cognitive and Neurophysiological Recovery Following Electroconvulsive Therapy: A Study Protocol. Front Psychiatry 9: 171, May 2018.

Mashour GA, Kelz MB: Systems Neuroscience: The Exciting Journey to Oblivion. Current Biology 28(5): R223-4, Mar 2018.

McKinstry-Wu A, Carspecken CW, Proekt A, Kelz MB: Xenon Anesthesia and CT: Noninvasive Measures of Brain Anesthetic Concentration. Methods in enzymology 602: 289-98, 2018.

Shortal Brenna P, Reitz Sarah L, Aggarwal Adeeti, Meng Qing C, McKinstry-Wu Andrew R, Kelz Max B, Proekt Alex: Development and validation of brain target controlled infusion of propofol in mice. PLoS one 13(4): e0194949, 2018.

Wasilczuk AZ, Maier KL, Kelz MB: The Mouse as a Model Organism for Assessing Anesthetic Sensitivity. Methods in enzymology 602: 211-228, 2018.

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Last updated: 10/30/2019
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