Department of Anesthesiology and Critical Care

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John T. Farrar, M.D., Ph.D.

Professor of Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Member, University of Pennsylvania Cancer Center, Philadelphia, PA
Attending Staff, Penn Pain Medicine Center, Dept. of Anesthesia, Hospital of the University of Pennsylvania, University of Pennsylvania Health System, Philadelphia, PA
Clinical Associate, Department of Neurology, University of Pennsylvania, Philadelphia PA
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA
Co-Director, Biostatistics Analysis Center, Biostatistical and Epidemiology Consulting Center, Center for Clinical Epidemiology and Biostatistics
Co-Director, Master of Science in Clinical Epidemiology Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
Expert Review Panelist, UK Research and Innovation - MRC - Advanced Pain Discovery Platform (APDP)
Department: Biostatistics and Epidemiology

Contact information
Room 816, Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-898-5802
Fax: 215-573-5315
Graduate Group Affiliations
ScB. (Biology, Computer Science minor)
Brown University, 1976.
The University of Rochester School of Medicine, 1981.
M.S.C.E. (Center for Clinical Epidemiology and Biostatistics)
The University of Pennsylvania, 2000.
Ph.D. (Graduate Group - Biostatistics and Epidemiology)
The University of Pennsylvania School of Medicine, 2004.
Post-Graduate Training
Residency Program in Internal Medicine, Children's Hospital of San Francisco, CA, 1981-1983.
Residency Program in Neurology, The New York Hospital, Cornell Medical Center, New York, NY, 1984-1986.
Chief Resident in Neurology, The New York Hospital, Cornell Medical Center, New York, NY, 1986-1987.
Neuro-Oncology and Pain Fellow, Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, 1987-1988.
Fellowship in Clinical Epidemiology and Biostatistics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, 1993-2000.
American Board of Psychiatry and Neurology (Recertified - 2019), 1995.
Subspecialty in Pain Medicine, American Board of Psychiatry and Neurology (Recertified – 2014), 2004.
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Description of Research Expertise

Research related to pain including the use of new pain medications, brain function in people with pain, complementary and alternative therapies, and new methodologies for understanding how patients report their pain in clinical trials. Current research includes ongoing studies of acupuncture for the treatment of pain in osteo-arthritis patients and chronic fatigue in cancer patients, brain imaging of patients with pain, and studies of cancer treatment related pain.

Description of Clinical Expertise

Focuses on all aspects of pain and symptom therapy in cancer patients as a member of the Symptom and Palliative Care Team and as a collaborator in the development of a multi-disciplinary program for the evaluation and treatment of patients with pain.

Selected Publications

Farrar JT, Bilker WB, Cochetti PT, Argoff CE, Haythornthwaite J, Katz NP, Gilron I: Evaluating the Stability of Opioid efficacy over 12 months in patients with chronic noncancer pain who initially demonstrate benefit from extended release oxycodone or hydrocodone: harmonization of Food and Drug Administration patient-level drug safety study data. Pain July 2021 Notes: doi: 10.1097/j.pain.0000000000002331. Online ahead of print.

Giordano NA, Richmond TS, Farrar JT, Trip CC, Buckenmaier, Gallagher RM, Polomano RC: Differential Pain Presentations Observed Across Post-Traumatic Stress Disorder Symptom Trajectories After Combat Injury. Pain Medicine June 2021 Notes: doi: 10.1093/pm/pnab204. Online ahead of print.

Coyne KS, Barsdorf AI, Currie BM, Poon JL, Mazière JY, Pierson RF, Butler SF, Schnoll SH, Farrar JT, Fisher HJ, Franks MJ Jr.: Insight Into Chronic Pain in the United States: Descriptive Results From the Prescription Opioid Misuse and Abuse Questionnaire (POMAQ) Validation Study. Current Medical Research and Opinion 37(3): 483-492, March 2021 Notes: doi: 10.1080/03007995.2020.1865889. Epub 2021 Jan 18.

Coyne KS, Barsdorf AI, Currie BM, Butler SF, Farrar JT, Mazière JY, Pierson RF, Fisher HJ, Bukhari AA, Schnoll SH: Construct validity and reproducibility of the Prescription Opioid Misuse And Abuse Questionnaire (POMAQ). Current Medical Research and Opinion 37(3): 493-503, March 2021 Notes: doi: 10.1080/03007995.2020.1865890. Epub 2021 Jan 18.

Gewandter JS, Dworkin RH, Turk DC, Farrar JT, Fillingim RB, Gilron I, Markman JD, Oaklander AL, Polydefkis MJ, Raja SN, Robinson JP, Woolf CJ, Ziegler D, Ashburn MA, Burke LB, Cowan P, George SZ, Goli V, Graff OX, Iyengar S, Jay GW, Katz J, Kehlet H, Kitt RA, Kopecky EA, Malamut R, McDermott MP, Palmer P, Rappaport BA, Rauschkolb C, Steigerwald I, Tobias J, Walco GA: Research Design Considerations for Chronic Pain Prevention Clinical Trials: IMMPACT Recommendations. Pain 6(1): e886, Jan 2021.

Sayegh RR, Yu Y, Farrar JT, Kuklinski E, Shtein RM, Asbell PA, Maguire MG, the Dry Eye Assessment and Management (DREAM) Study Research Group.: Ocular Discomfort and Quality of Life Among Patients in the Dry Eye Assessment and Management(DREAM) Study. Cornea Dec 2020 Notes: Online ahead of print. doi: 10.1097/ICO.0000000000002580.

Stephens-Shields AJ, Farrar JT, Ellenberg SS, Storer TW, Gill TM, Basaria S, Pahor M, Cauley JA, Ensrud KE, Preston P, Cella D, Snyder PJ, Bhasin S: Clinically Important Differences for Mobility Measures Derived from the Testosterone Trials. Journal of the American Geriatrics Society Nov 2020 Notes: Online ahead of print. doi: 10.1111/jgs.16942.

Hersh EV, Moore PA, Grosser T, Polomano RC, Farrar JT, Saraghi M, Juska SA, Mitchell CH, Theken KN: Nonsteroidal Anti-Inflammatory Drugs and Opioids in Postsurgical Dental Pain. Journal of Dental Research 99(7), July 2020.

Kohli AA, Vossough A, Mallery RM, Woo JH, Sheldon CA, Paley GL, Digre KB, Friedman DI, Farrar JT, McCormack SE, Liu GT, Szperka CL: Magnetic Resonance Imaging Findings in Pediatric Pseudotumor Cerebri Syndrome. Pediatric Neurology 99: 31-39, Oct 2019.

Theken KN, Hersh EV, Lahens NF, Lee HM, Li X, Granquist EJ, Giannakopoulos HE, Levin LM, Secreto SA, Grant GR, Detre JA, FitzGerald GA, Grosser T, Farrar JT: Variability in the Analgesic Response to Ibuprofen Is Associated With Cyclooxygenase Activation in Inflammatory Pain. Clinical Pharmacology and Therapeutics 106(3): 632-641, Sept 2019.

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Last updated: 11/11/2021
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