Colin A Ellis, MD
Assistant Professor of Neurology at the Hospital of the University of Pennsylvania
Assistant Professor of Neurology, University of Pennsylvania,
Department of Neurology
Department: Neurology
Contact information
University of Pennsylvania
Department of Neurology
3 West Gates Building
Philadelphia, PA 19104
Department of Neurology
3 West Gates Building
Philadelphia, PA 19104
Office: 215-349-5166
Fax: 215-349-5733
Fax: 215-349-5733
Publications
Education:
ScB (Cog. Neuroscience)
Brown University, 2005.
MD (Medicine)
University of Pennsylvania School of Medicine, 2012.
ScB (Cog. Neuroscience)
Brown University, 2005.
MD (Medicine)
University of Pennsylvania School of Medicine, 2012.
Post-Graduate Training
Intern in Medicine, Hospital of the University of Pennsylvania, 2012-2013.
Resident in Epilepsy, Hospital of the University of Pennsylvania, 2013-2016.
Fellow in Epilepsy, Hospital of the University of Pennsylvania, 2016-2017.
Fellow, Epilepsy & Genetics, University of Melbourne and Austin Health Melbourne, Australia, 2017-2018.
Post-Doctoral Research Fellow, University of Pennsylvania, 2017-2019.
Intern in Medicine, Hospital of the University of Pennsylvania, 2012-2013.
Resident in Epilepsy, Hospital of the University of Pennsylvania, 2013-2016.
Fellow in Epilepsy, Hospital of the University of Pennsylvania, 2016-2017.
Fellow, Epilepsy & Genetics, University of Melbourne and Austin Health Melbourne, Australia, 2017-2018.
Post-Doctoral Research Fellow, University of Pennsylvania, 2017-2019.
Certifications
Diplomat - American Board of Psychiatry and Neurology , 2016.
Epilepsy Certification, American Board of Psychiatry and Neurology, 2017.
Permanent linkDiplomat - American Board of Psychiatry and Neurology , 2016.
Epilepsy Certification, American Board of Psychiatry and Neurology, 2017.
Description of Clinical Expertise
Dr. Ellis is a neurologist with expertise in the management of seizures and epilepsy. This includes expertise in EEG, anti-seizure medications, surgical treatment of epilepsy, neurostimulation, and implantable devices. Dr. Ellis also has clinical expertise in genetics and the genetic causes of epilepsy. He sees patients with epilepsy for genetic evaluations at the University of Pennsylvania and the Children's Hospital of Philadelphia.Description of Research Expertise
Dr. Ellis's research is focused on the genetic basis of epilepsy. He is particularly interested in the discovery of genes that cause epilepsy; the heritability of epilepsy within families; and the use of genetics to improve the diagnosis and treatment of epilepsy. An additional research focus in the mining of electronic health records using natural language processing.Selected Publications
Decker BM, Turco A, Xu J, Terman SW, Kosaraju N, Jamil A, Davis KA, Litt B, Ellis CA, Khankhanian P, Hill CE.: Development of a natural language processing algorithm to extract seizure types and frequencies from the electronic health record. Seizure 101: 48-51, Oct 2022.Stamberger H, Crosiers D, Balagura G, Bonardi CM, Basu A, Cantalupo G, Chiesa V, Christensen J, Dalla Bernardina B, Ellis CA, Furia F, Gardiner F, Giron C, Guerrini R, Klein KM, Korff C, Krijtova H, Leffner M, Lerche H, Lesca G, Lewis-Smith D, Marini C, Marjanovic D, Mazzola L, McKeown Ruggiero S, Mochel F, Ramond F, Reif PS, Richard-Mornas A, Rosenow F, Schropp C, Thomas RH, Vignoli A, Weber Y, Palmer E, Helbig I, Scheffer IE, Striano P, Møller RS, Gardella E, Weckhuysen S.: Natural History Study of STXBP1-Developmental and Epileptic Encephalopathy Into Adulthood. Neurology 99(3): e221-e233, Jul 2022.
Oliver KL*, Ellis CA*, Scheffer IE, Ganesan S, Leu C, Sadleir LG, Heinzen EL, Mefford HC, Bass AJ, Curtis SW, Harris RV; Epi4K Consortium, Whiteman DC, Helbig I, Ottman R, Epstein MP, Bahlo M, Berkovic SF.: Common risk variants for epilepsy are enriched in families previously targeted for rare monogenic variant discovery. EBioMedicine 81: 104079, Jul 2022.
Campbell C, Leu C, Feng YA, Wolking S, Moreau C, Ellis C, Ganesan S, Martins H, Oliver K, Boothman I, Benson K, Molloy A, Brody L; Epi4K Collaborative; Genomics England Research Consortium, Michaud JL, Hamdan FF, Minassian BA, Lerche H, Scheffer IE, Sisodiya S, Girard S, Cosette P, Delanty N, Lal D, Cavalleri GL; Epi25 Collaborative.: The role of common genetic variation in presumed monogenic epilepsies. EBioMedicine 81: 104098, Jul 2022.
Xian J, Parthasarathy S, Ruggiero SM, Balagura G, Fitch E, Helbig K, Gan J, Ganesan S, Kaufman MC, Ellis CA, Lewis-Smith D, Galer P, Cunningham K, O'Brien M, Cosico M, Baker K, Darling A, Veiga de Goes F, El Achkar CM, Doering JH, Furia F, García-Cazorla Á, Gardella E, Geertjens L, Klein C, Kolesnik-Taylor A, Lammertse H, Lee J, Mackie A, Misra-Isrie M, Olson H, Sexton E, Sheidley B, Smith L, Sotero L, Stamberger H, Syrbe S, Thalwitzer KM, van Berkel A, van Haelst M, Yuskaitis C, Weckhuysen S, Prosser B, Son Rigby C, Demarest S, Pierce S, Zhang Y, Møller RS, Bruining H, Poduri A, Zara F, Verhage M, Striano P, Helbig I.: Assessing the landscape of STXBP1-related disorders in 534 individuals. Brain 145(5): 1668-1683, Jun 2022.
Ganguly TM, Ellis CA, Tu D, Shinohara RT, Davis KA, Litt B, Pathmanathan J.: Seizure Detection in Continuous Inpatient EEG: A Comparison of Human vs Automated Review. Neurology 98(22): e2224-e2232. May 2022.
Xie K, Gallagher RS, Conrad EC, Garrick CO, Baldassano SN, Bernabei JM, Galer PD, Ghosn NJ, Greenblatt AS, Jennings T, Kornspun A, Kulick-Soper CV, Panchal JM, Pattnaik AR, Scheid BH, Wei D, Weitzman M, Muthukrishnan R, Kim J, Litt B, Ellis CA*, Roth D*.: Extracting seizure frequency from epilepsy clinic notes: a machine reading approach to natural language processing. J Am Med Inform Assoc 29(5): 873-881, Apr 2022.
Galosi S, Edani BH, Martinelli S, Hansikova H, Eklund EA, Caputi C, Masuelli L, Corsten-Janssen N, Srour M, Oegema R, Bosch DGM, Ellis CA, Amlie-Wolf L, Accogli A, Atallah I, Averdunk L, Barañano KW, Bei R, Bagnasco I, Brusco A, Demarest S, Alaix AS, Di Bonaventura C, Distelmaier F, Elmslie F, Gan-Or Z, Good JM, Gripp K, Kamsteeg EJ, Macnamara E, Marcelis C, Mercier N, Peeden J, Pizzi S, Pannone L, Shinawi M, Toro C, Verbeek NE, Venkateswaran S, Wheeler PG, Zdrazilova L, Zhang R, Zorzi G, Guerrini R, Sessa WC, Lefeber D, Tartaglia M, Hamdan FF, Grabińska KA, Leuzzi V.: De novo DHDDS variants cause a neurodevelopmental and neurodegenerative disorder with myoclonus. Brain 145(1): 208-223, Mar 2022.
Shah YB, Lin P, Chen S, Zheng A, Alcaraz W, Towne MC, Gabriel C, Bhoj EJ, Lambert MP, Olson TS, Frank DM, Ellis CA, Babushok DV.: Inherited bone marrow failure with macrothrombocytopenia due to germline tubulin beta class I (TUBB) variant. Br J Haematol in press, 2022.
Ellis CA, Ottman R: Genetic Epidemiology of Epilepsy. Epilepsy – A Comprehensive Textbook, 3rd edition. Engel J & Pedley TA (eds.). Wolters Kluwer Publishers, Philadelphia, 2022 Notes: in-press.