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Nadia Dahmane, Ph.D.

Adjunct Associate Professor of Neurosurgery
Department: Neurosurgery

Contact information
University of Pennsylvania
Department of Neurosurgery
502C Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-0837
University of Paris 7-Denis Diderot (Biology of Aging), 1996.
Post-Graduate Training
Postdoctoral Researcher, New York University School of Medicine, The Skirball Institute, New York, NY, 1996-2000.
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> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Macyszyn, L., Akbari, H., Pisapia, J. M., Da, X., Attiah, M., Pigrish, V., Bi, Y., Pal, S., Davuluri, R. V., Roccograndi, L., Dahmane, N., Martinez-Lage, M., Biros, G., Wolf, R. L., Bilello, M., O'Rourke, D. M., Davatzikos, C.: Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques. Neuro Oncol 18(3): 417-25, 2016.

Huang, M., Liu, T., Ma, P., Mitteer, R. A., Jr., Zhang, Z., Kim, H. J., Yeo, E., Zhang, D., Cai, P., Li, C., Zhang, L., Zhao, B., Roccograndi, L., O'Rourke, D. M., Dahmane, N., Gong, Y., Koumenis, C., Fan, Y.: c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest 126(5): 1801-14, 2016.

Wang, Z., Deng, Z., Dahmane, N., Tsai, K., Wang, P., Williams, D. R., Kossenkov, A. V., Showe, L. C., Zhang, R., Huang, Q., Conejo-Garcia, J. R., Lieberman, P. M.: Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes. Proc Natl Acad Sci U S A 112(46): E6293-300, 2015.

Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ.: Pyrvinium attenuates hedgehog signaling downstream of smoothened. Cancer Res 74(17): 4811-21, 2014.

Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Carpio RV, Dahmane N, Robbins DJ, Capobianco AJ.: NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis. Cancer Res 74(17): 4741-51, 2014.

Baubet, V., Xiang, C., Molczan, A., Roccograndi, L., Melamed, S., Dahmane, N.: Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development 139(11): 1903-9, 2012.

Xiang, C., Baubet, V., Pal, S., Holderbaum, L., Tatard, V., Jiang, P., Davuluri, R. V., Dahmane, N.: RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ 19(4): 692-702, 2012.

Deng, Z., Wang, Z., Xiang, C., Molczan, A., Baubet, V., Conejo-Garcia, J., Xu, X., Lieberman, P. M., Dahmane, N.: Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma. J Cell Sci 125(Pt 18): 4383-94, 2012.

Demarest, R. M., Dahmane, N., Capobianco, A. J.: Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia. Blood 117(10): 2901-9, 2011.

Isaacs, A. K., Xiang, C., Baubet, V., Dahmane, N., Winkler, J. D.: Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors. Org Lett 13(19): 5140-3, 2011.

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Last updated: 02/01/2017
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