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Timothy H Lucas Jr., M.D., Ph.D.

Assistant Professor of Neurosurgery
Director, Translational Neuromodulation Laboratory, Department of Neurosurgery, University of Pennsylvania
Associate Director, Center for Neuroengineering & Therapeutics, University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street
3rd Floor Silverstein
Philadelphia, PA 19104
Office: 215-615-0578
Fax: 215-349-5534
Lab: 215-746-1336
Graduate Group Affiliations
B.S. (Neurobiological Sciences & Psychobiology)
University of Florida, 1996.
M.D. (Medicine)
University of Florida, 2001.
Ph.D. (Physiology & Biophysics)
University of Washington, 2009.
Post-Graduate Training
Intern in General Surgery, University of Washington, 2001-2002.
Resident in Neurological Surgery, University of Washington, 2002-2009.
Specialist Registrar in Neurological Surgery, St. George's National Healthcare Trust, London, England, UK, 2006-2007.
Chief Resident in Neurological Surgery, University of Washington, 2009-2010.
Fellow in Neurosurgical Oncology & Cerebrovascular Neurosurgery, University of Washington, 2010-2010.
Fellow in Neurosurgical Oncology Brain Mapping, University of California San Francisco, 2011-2011.
Clinical Experience in Stereotactic & Functional Neurosurgery, University of California San Francisco, 2011-2011.
American Board of Neurological Surgeons (Board Eligible), 2011.
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Description of Clinical Expertise

Epilepsy Surgery
Temporal Lobectomy
Minimally invasive neurosurgery
Laser Neurosurgery
Endoscopic Surgery
Sports Neurosurgery
Cortisectomy / Topectomy
Corpus Callostomy / Functional Disconnection Surgery
Trigeminal neuralgia
Microvascular decompression
Stereotactic and Functional Neurosurgery
Movement Disorder Surgery (Parkinson's Disease, Essential Tremor, Dystonia)
Glioma Surgery (Low Grade, High Grade, Adult, Pediatric)
Insular Lesions
Brain Mapping (Speech, Motor, Sensory; cortical and subcortical)
Extraoperative Brain Mapping
Brain-machine interface / Brain-computer interface
Spine Disorders
Spinal Fusion
Skull base surgery
Brain Plasticity
Eloquent Cortex Lesions (motor, sensory, speech, visual cortex)
Traumatic brain and spine injury

Description of Research Expertise

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Spinal Cord Stimulation and Mapping

Selected Publications

Yu, K; Lyu, H; Richardson, AG; Lucas, TH; Kuzum, D: Flexible neural electrode array based-on Porous grapheme for cortical microstimulation and sensing. Scientific Reports (accepted with revision) 2016

Richardson, Andrew G, Weigand, Pauline K, Sritharan, Srihari Y, Lucas, Timothy H: A chronic neural interface to the macaque dorsal column nuclei. Journal of neurophysiology 115(5): 2255-2264, 2016.

Liu, X; Zhang, M; Xiong, T; Richardson, AG; Lucas, TH; Chin, PS; Etienne-Cummings, R; Tran, TD, J Van der Spiegel: A fully integrated wireless compressed sensing neural signal acquisition system for chronic recording and brain machine interface. IEEE Trans Biomed Circuits and Systems (in press) 2016.

Zhang, M; Liu, X; Sacks, J; Richardson, AG; Lucas, TH; Van der Spiegel, J: A virtual trackpad: an electromyography based, wireless, real-time, low-power, embedded hand gesture recognition system using an event driven artificial neural network. IEEE Trans Biomed Circuits and Systems 2016.

Thawani, J; Vaughn, K; Lucas TH: Image guidance and robotics in neurosurgery. Robotics in Surgery 2016.

Abdullah, K; Chen, HI; Lucas, TH: Safety of topical vancomycin powder in neurosurgery. Surgical Neurology International (in press) 2016.

Khambhati, A; Bassett, DS; Oomen, BS; Chen, SH; Lucas TH; Davis, DA; Litt, B: Recurring functional architecture predicts dynamic network interactions during octal and interictal states in human neocortical epilepsy. eNeuro (in press) 2016.

Khambhati, A; Davis, KA; Lucas, TH; Litt, B; Bassett, DS : Virtual cortical resection reveals push-pull network control mechanism preceding seizure evolution. Neuron (in press) 2016.

Liu, Xilin, Zhang, Milin, Richardson, Andrew G, Lucas, Timothy H, Van der Spiegel, Jan: A 12-channel bidirectional neural interface chip with integrated channel-level feature extraction and PID controller for closed-loop operation. IEEE Transactions in Biomed Circuits and Systems (in press). IEEE, Page: 1-4, 2016.

Thawani, Jayesh P, Lucas, Timothy H: Open traumatic brain injury by nail gun resulting in a persistent vegetative state. Neurology 86(14): 1358-1359, 2016.

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Last updated: 07/11/2016
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