Faculty & Staff

Brian B. Avants, Ph.D.

faculty photo
Research Assistant Professor of Radiology
Research Associate, University of Pennsylvania, Department of Radiology
Department: Radiology

Contact information
Penn Image Computing and Science Lab
Richards, 6th Floor
3700 Hamilton Walk
Philadelphia, PA 19104
Office: (215) 870 0787
B.A. (Physics)
New College of Florida, 1997.
M.S. (Applied Physics)
Columbia University, 1999.
M.S. (Computer Science)
University of Pennsylvania, 2002.
Ph.D. (Bioengineering)
University of Pennsylvania, 2005.
Post-Graduate Training
Research Fellow, University of Pennsylvania, 2006-2010.
Human Subjects Research Training University of Pennsylvania, 2013.
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Description of Research Expertise

Medical Image Registration

Image-Based Analysis of Pediatric Brain Development

Imaging and Clinical Effects of Frontotemporal Dementia and variants

Imaging and Clinical Effects in Traumatic Brain Injury

Lesion Analysis in the Brain

Cortical Thickness Analysis

Statistical Image Analysis

Visualization and Computation

Numerical Methods


Description of Other Expertise

Software: PipeDream - Pipedream encodes “best practice” cross-sectional and longitudinal neuroimaging studies of cortical thickness, jacobian-based morphometry and diffusion tensor imaging in a generic Pipelining infrastructure.

Software: Insight Surface Analysis and Normalization Environment (InSane, available by request): Cortical surface analysis tools for visualization, curve-guided normalization and flattening based analyses of functional and anatomical brain imagery.

Software: Advanced Normalization Tools (ANTS, http://sourceforge.net/projects/advants) : Top-Rated normalization toolkit, designed for DT and T1 MRI of the brain. Dr. Avants is the lead theoretician, designer and developer of this toolkit.

Selected Publications

Avants, B.B.; Hackman, D.; Betancourt, L.; Lawson, G.M.; Hurt, H.; Farah, M.J.: Relation of Childhood Home Environment to Cortical Thickness in Late Adolescence: Specifically of Experience and Timing. PLOS One 2016.

Adler, D.H.; Pluta, J.; Kadivar, S.; Craige, C.; Gee, J.C.; Avants, B.B.; Yushkevich, P.A.: Histology-derived volumetric annotation of the human hippocampal subfields in postmortem MRI. Neuroimage 84: 505-523, 2015.

Avants, B.B.; Johnson, H.J.; Tustison, N.J.: Neuroinformatics and the Insight ToolKit. Frontiers in neuroinformatics 9, 2015.

Betancourt, L.; Avants, B.B.; Farah, M.J.; Brodsky, N.L.; Wu, J.; Ashtari, M.; Hurt, H.: Effect of socioeconomic status (SES) disparity on neural development in female African-American infants at age 1 month. Developmental Science 2015.

Avants, B.B.; Duda, J.T.; Kilroy, E.; Krasileva, K.; Jann, K.; Kandel, B.T.; Tustison, N.J.; Yan, L.; Jog, M.; Smith, R.; Want, Y.; Dapretto, M.; Wang, D.J.J.: The pediatric template of brain perfusion. Science Data 2(150003), 2015.

Kandel, B.M.; Avants, B.B.; Gee, J.C.; Arnold, S.E.; Wolk, D.A.: Neuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-B in Mild Cognitive Impairment. J Alzheimer's Disease 46(4): 901-912, 2015.

Kandel, B.M.; Wang, D.J.J.; Gee, J.C.; Avants, B.B.: Eigenanatomy: sparce dimensionality reduction for multi-modal medical image analysis. Methods 73: 43-53, 2015.

Kandel, B.M.; Wang, D.J.J.; Detre, J.A.; Gee, J.C.; Avants, B.B.: Decomposing cerebral blood flow MRI into functional and structural components; a non-local approach based on prediction. Neuroimage 105: 156-170, 2015.

Isgum, I.; BEnders, M.J.N.L.; Avants, B.; Cardoso, M.J.; Counsell, S.J.; Gomez, E.F.; Gui, L.; HAssppi, P.S.; Kersbergen, K.J.; Makropoulos, A.; Melbourne, A.; Moeskops, P.; Mol, C.P.; Kuklisova-Murgasova, M.; Ruechkert, D.; Schnabel, J.A.; Srhoj-Egekher, V.; Wu, J.;Wang, S.; de Vries, L.S.; Viergever, M.A.: Evaluation of automatic neonatal brain segmentation algorithms: The NeoBrainS12 challenge. Med Image Anal 20(1): 135-151, 2015.

Pustina, D.; Avants, B.B.; Sperling, M.; Gorniak, R.; He, X.; Doucet, G.; Barnett, P.; Mintzer, S.; Sharan, A. & Tracy, J.: Predicting the laterality of temporal lobe epilepsy from PET, MRI, and DTI: A multimodal study. Neurimage Clin, 9(20-31), 2015.

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Last updated: 10/09/2015
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